Intranasal budesonide in children affected by persistent allergic rhinitis and its effect on nasal patency and Nasal Obstruction Symptom Evaluation (NOSE) score

2015 ◽  
Vol 31 (3) ◽  
pp. 391-396 ◽  
Author(s):  
Anna Maria Zicari ◽  
Francesca Occasi ◽  
Montanari Giulia ◽  
Luciana Indinnimeo ◽  
Giovanna De Castro ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Nasal Obstruction ◽  
Nasal Patency ◽  
Persistent Allergic Rhinitis ◽  
Symptom Evaluation

scholarly journals Respiratory mode, nasal patency and palatine dimensions

CoDAS ◽  
2015 ◽  
Vol 27 (2) ◽  
pp. 201-206 ◽  
Author(s):  
Maria Elaine Trevisan ◽  
José Humberto Bellinaso ◽  
Andrielle de Bitencourt Pacheco ◽  
Luciana Barros Augé ◽  
Ana Maria Toniolo da Silva ◽  
...  
Keyword(s):  
Nasal Obstruction ◽  
Negative Correlation ◽  
Hard Palate ◽  
Nasal Patency ◽  
Nasal Breathing ◽  
Nose Scale ◽  
Symptom Evaluation ◽  
Plaster Models ◽  
Digital Caliper ◽  
Peak Nasal Inspiratory Flow

Purpose: To investigate the influence of breathing mode and nasal patency in the dimensions of the hard palate by comparing mouth breathing (MB) and nasal breathing (NB) adults. Methods: Seventy-seven individuals, distributed into the MB group (n=38) and the NB group (n=39), of both genders and aged between 18 and 30 years old, took part in the study. The respiratory mode diagnosis was based on anamnesis, physical characteristics, and otorhinolaryngological examination. The volunteers were evaluated in terms of nasal patency, with a peak nasal inspiratory flow (PNIF) meter, and obstruction symptoms, by a Nasal Obstruction Symptom Evaluation (NOSE) scale, and had their transversal and vertical hard palate dimensions measured with a digital caliper in plaster models. Results: Comparing both groups, the MB group presented significantly higher values in the NOSE scale, lower values in the PNIF, lower values in the transversal distance of the palate in the intercanine region, and significantly higher values in the vertical distance in the regions of the first and second premolars and molars. There was a negative correlation between PNIF and NOSE, and a positive correlation between PNIF and transversal distance of the palate in the region of the first premolars. Conclusion: MB adults presented reduced nasal patency and a higher degree of nasal obstruction symptoms. The hard palate was morphologically narrower and deeper in adults with the MB mode compared to the NB mode. Moreover, it was concluded that the smaller the nasal patency, the greater the obstruction symptoms and the narrower the hard palate.

scholarly journals Primary school children often underestimate their nasal obstruction

2016 ◽  
Vol 54 (2) ◽  
pp. 164-169
Author(s):  
Francesca Occasi ◽  
Marzia Duse ◽  
Tommaso Vittori ◽  
Anna Rugiano ◽  
Giancarlo Tancredi ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Secondary School ◽  
Primary School ◽  
Nasal Obstruction ◽  
School Children ◽  
Primary School Children ◽  
Nasal Resistance ◽  
Nasal Patency ◽  
School Aged Children ◽  
Subjective Sensation

Background: No consensus has ever been reached about the correlation between nasal resistance and the subjective sensation of nasal patency. The aim of the present study was to better de ne whether primary school and secondary school aged children correctly estimate their nasal obstruction. Materials and methods: Two hundred eighty four children (168 males and 116 female) aged between 6 and 14 years (9.5+2.9 years) affected by Pediatric Allergic Rhinitis underwent Rhinomanometry and they were considered as correctly estimating their nasal obstruction when the grade of nasal patency corresponded to the severity of the NOSE score, overestimating when the grade of nasal patency was <1 when compared to the severity of the score, underestimating when the grade of nasal patency was >1 when compared to the severity of the score. Results: Correlation between NOSE score and nasal patency was statistically significant (r -0.74; p<0.001). Children between 6 and 9 years of age underestimate (43.7%) and children >12 overestimate (34.7%) their symptoms more frequently than children among other age ranges (p<0.001). Conclusion: Although NOSE score approximately allow to quantify nasal obstruction, in children, especially between 6 and 9 years of age, an objective measurement of nasal patency should be performed to better define the therapeutic approach.

scholarly journals Comparison of Fluticasone Furoate and Cetirizine Versus Fluticasone Furoate and Montelukast in Allergic Rhinitis

2021 ◽  
Vol 51 (1) ◽  
Author(s):  
Bobby Pardomuan Sitompul ◽  
Rus Suheryanto ◽  
Hendradi Surjotomo
Keyword(s):  
Allergic Rhinitis ◽  
Nasal Obstruction ◽  
Eosinophil Count ◽  
Treatment Result ◽  
Fluticasone Furoate ◽  
Double Blind ◽  
Once Daily ◽  
Persistent Allergic Rhinitis ◽  
Group 2 ◽  
Group 1

Background: The complexity of treatment in allergic rhinitis remains to be a global challenge. The medical treatment option for moderate-severe persistent allergic rhinitis is the combination of intranasal corticosteroid (INCS) and oral antihistamine or leukotriene receptor antagonist (LTRA). The combination INCS with LTRA is selected based on the presence of asthma. Purpose: To determine the effect of fluticasone furoate plus cetirizine administration comparing fluticasone furoate plus montelukast on nasal eosinophils count and clinical improvement in patients with moderate-severe persistent allergic rhinitis. Method: This study was purely experimental research with the study design randomized clinical trial, double-blind, pre and post test control. Patient were divided into two group. Group-1 received intranasal fluticasone furoate 110 μg once daily and oral cetirizine 10mg and Group-2 received intranasal fluticasone furoate 110 μg once daily and Montelukast 10mg. The treatment efficacy is assessed from nasal eosinophil count and total five symptoms score (T5SS) based on Visual Analogue Scale (VAS) before and 4 weeks after treatment. Result: Both groups show a decrease in the nasal eosinophil count and T5SS score based on VAS before and after treatment (p< 0.05). The group-2 shows a statistically significant improvement in nasal obstruction and rhinorrhea compare to the group-1 (p <0.05). The decrease in nasal eosinophil count and T5SS is higher in the group-2 than the group-1, however, it is not statistically significant. Conclusion: The combination of fluticasone furoate and montelukast is more effective in reducing nasal obstruction and rhinorrhea than the combination of fluticasone furoate and cetirizine.

Sleep Apnea and Nasal Patency

1988 ◽  
Vol 2 (4) ◽  
pp. 177-182 ◽  
Author(s):  
Richard P. Millman
Keyword(s):  
Allergic Rhinitis ◽  
Sleep Apnea ◽  
Nasal Obstruction ◽  
Successful Treatment ◽  
Normal Subjects ◽  
Sleep Disruption ◽  
Nasal Patency ◽  
Daytime Drowsiness ◽  
Clinical Investigations ◽  
Nasal Passages

Clinical investigations over the last decade have revealed that sleep may not be the benign rejuvenating state it was once considered. Sleep apnea is now frequently recognized, and it is clear that patency of the nasal passages and the nasopharynx is crucial for successful treatment of the syndrome. Furthermore, partial or complete nasal obstruction even in normal subjects can cause sleep disruption, hypopneas, and apneas. This may partially explain some of the daytime drowsiness seen in patients with conditions such as allergic rhinitis.

Effects of Acute Alcohol Intake on Nasal Patency

2021 ◽  
pp. 194589242110623
Author(s):  
Yuzhoujia Deng ◽  
Chengshuo Wang ◽  
Shen Shen ◽  
Xiaozhe Yang ◽  
Hongfei Lou ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Alcohol Consumption ◽  
Nasal Obstruction ◽  
Alcohol Intake ◽  
Blood Alcohol Concentration ◽  
Heavy Drinking ◽  
Nasal Patency ◽  
Objective Evidence ◽  
Heavy Drinkers ◽  
Baseline Values

Background Acute alcohol intake may influence nasal patency; however, there is lack of objective evidence. Objective The aim of this study was to evaluate the effects of acute alcohol intake on nasal patency employing both subjective and objective measures. Methods A total of 31 participants were classified into 2 groups of non-heavy drinkers (n = 17) and heavy drinkers (n = 14). Both groups consumed wine in 1 h and were assessed for subjective nasal symptoms and objective nasal patency, using rhinomanometry and acoustic rhinometry, at baseline and at 0.5, 2, and 6 h post-alcohol consumption. Results Alcohol consumption significantly increased nasal obstruction from baseline values in both heavy and non-heavy drinking groups. Total nasal volume (TNV) and the minimal cross-sectional area (MCA) were significantly decreased and nasal airway resistance (NAR) significantly increased from baseline values by 2 h post-alcohol consumption for both heavy and non-heavy drinking groups ( P < .05). Significant differences were found in TNV, MCA, and NAR between baseline and post-drinking in allergic rhinitis subjects; with no significant differences in MCA and NAR in subjects without allergic rhinitis. Pulse rate (PR) and temperature (T) were elevated, and blood pressure (BP) was decreased after alcohol consumption ( P < .05). Blood alcohol concentration (BAC) was not significantly correlated with nasal patency with regard to any subjective or objective measurement. Conclusion Acute alcohol consumption may impair nasal patency, independent of the amount consumed. Individuals with allergic rhinitis may be more prone to nasal obstruction after alcohol consumption than those without allergic rhinitis.

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