CASE REPORT ABOUT THE PROSTHETICS WITH INTRAOSSEOUS IMPLANTS OF THE MAXILLA

During the rehabilitation of patients with the atrophic maxilla, the dental medicine doctor may faced before the challenge of achieving the exact placing of the intraosseous implants. We would like to present you the case of a 33-year woman with a prosthetic of implants after a Rehermanns plastic. The clinical and radiographic examinations show an absorbed maxilla with the horizontal and vertical bone deficit. The patient used a placeholder till the complete bone restoration after the surgical intervention. She did not want a final rehabilitation of the defect using a bridge-like structure due to the necessary intervention of the teeth neigboring the defect. The decision about the placing of intraosseous implants was made after the CBCT examination. The control examinations made after 6 months, 1 year, 3 years, and 5 years show satisfying results in regard to the function and aesthetics, and also the lack of subjective sensation for the patient.

POSSIBILITIES OF TREATMENT OF I NFECTED ULCERS OF THE LOWER EXTREMITIES IN CHRONIC VENOUS INSUFFICIENCY WITHOUT THE USE OF ANTIBIOTICS

Summary. Introduction. Purulent diseases and purulent complications in modern medicine remain a complex and not always a positive problem, because in the development of such diseases is quite prominent microbial factor. Overcoming the latter is getting harder every year. The urgency of the problem. The fact is that before our eyes, almost exponentially, the number of microorganisms resistant to existing antibiotics is increasing. Not to mention the toxic effects of many of them on certain organs due to their natural tropism, we note allergic effects, individual intolerance and dysbacterial effects, we note that the cost of some drugs for 1–2 days of use is equal to pension (monthly «income» of most retirees). Given this, you need to look for an opportunity to do without the use of antibiotics, which determines the urgency of the problem. Goal. Explore the possibility of treating infected lower extremity ulcers without the use of antibiotics. Materials and methods. The possibility of treating purulent ulcers of the lower extremities on the background of chronic venous insufficiency by using apatite polymeric drainage bandage based on hydroxyapatite supplemented with zinc oxide has been studied. Results and discussion. Polyvalent microbial association was established in 100 % of patients, staphylococcal colonization prevailed in 75 % of them. On 3–4 days of treatment, a decrease in inflammation, regression of symptoms, reduction of microbial insemination, the appearance of signs of repair, improvement of foot function were recorded. Conclusions. 1) The possibility of treating infected wounds by using apatite polymer drainage bandage has been confirmed; 2) On 3–4 days of application of the drainage bandage there is a regression of the inflammatory process in the area of the ulcer; 3) Microbial contamination of the wound surface for 4 days is reduced from 108 to 73.5 CFU/ml; 4) Subjective sensation and foot function improve by 3–4 days of treatment.

Trigeminal impairment in treatment-refractory chronic nasal obstruction

BACKGROUND: Patients with anatomically unexplained, chronic nasal obstruction (CNO) that is refractory to medical treatment pose a challenge for clinicians. A surgical solution, addressing mechanical obstacles, is unsuited for these patients. CNO may result from disrupted airflow perception due to activation of the intranasal trigeminal system; therefore, aim of this study is to evaluate if intranasal trigeminal function of these CNO patients is decreased. METHODS: In this retrospective cross-sectional study, we compared 143 CNO patients and 58 healthy volunteers, between 18 to 80 years old. We assessed nasal patency by means of rhinomanometry (RM) and measured susceptibility of intranasal trigeminal system by the trigeminal lateralization task (TLT). RESULTS: TLT scores were significantly lower in CNO patients compared to controls (p less than 0.001), but RM scores were not different between groups. Accordingly, TLT allowed to identify CNO patients with an accuracy of the area under the curve (AUC) of 0.78, while the value for RM was at chance (AUC=0.47). CNO patients showed normal reaction to vasoconstrictive agents with significantly lower RM values after Xylomethazoline application. CONCLUSION: Results suggest that reported nasal obstruction in CNO patients without any obvious anatomical obstacle and resistant to medical treatment may be linked to decreased perception of nasal airflow rather than physical obstruction. In this sub-set of CNO patients, trigeminal testing more adequately reflects the reported obstruction than nasal resistance assessment does. In future studies, the relation of the trigeminal status and the subjective sensation of nasal obstruction needs to be addressed with validated patient rated outcome measures (PROMs).

A digitization theory of the Weber–Fechner law

Since the publication of Shannon’s article about information theory, there have been many attempts to apply information theory to the field of neuroscience. Meanwhile, the Weber–Fechner law of psychophysics states that the magnitude of a subjective sensation of a person increases in proportion to the logarithm of the intensity of the external physical-stimulus. It is not surprising that we assign the amount of information to the response in the Weber–Fechner law. But no one has succeeded in applying information theory directly to that law: the direct links between information theory and that response in the Weber–Fechner law have not yet been found. The proposed theory unveils a link between information theory and that response, and differs subtly from the field such as neural coding that involves complicated calculations and models. Because our theory targets the Weber–Fechner law which is a macroscopic phenomenon, this theory does not involve complicated calculations. Our theory is expected to mark a new era in the fields of sensory perception research. Our theory must be studied in parallel with the fields of microscopic scale such as neural coding. This article ultimately aim to provide the fundamental concepts and their applications so that a new field of research on stimuli and responses can be created.

Effect of Gazpacho, Hummus and Ajoblanco on Satiety and Appetite in Adult Humans: A Randomised Crossover Study

Nowadays, overweight and obesity has reached an epidemic level around the world. With the aim to tackle them, an interesting strategy is the study of food and ingredients with satiety properties. In addition to reducing food and/or calorie intake, this type of foods must be included as part of a healthy diet. With regard to this, it is well known that the Mediterranean Diet (MD) is a feeding pattern that helps us to maintain good health, providing an adequate intake of micronutrients and active compounds. With this background, the main aim of this research was to identify MD foods with a high satiating potential capacity. For this purpose, three typical foods of the Mediterranean region, mainly based on vegetables, were selected: hummus, ajoblanco and gazpacho. As a control, white bread was used. Twenty-four human healthy volunteers consumed a standard breakfast followed by the different typical Mediterranean foods, and then the subjective sensation of hunger and satiety for each food was assessed by visual analogue scales (VAS) during 3 h. Subsequently, volunteers had ad libitum access to a standard meal. The results indicate that gazpacho showed the highest satiating scores, despite the fact that it was not the food that provided the highest protein or fibre amount. More studies of this type are needed to determine the proportion and/or combination of ingredients from these classical Mediterranean recipes that could enhance human satiety.

Abdominothoracic Postural Tone Influences the Sensations Induced by Meal Ingestion

Postprandial objective abdominal distention is frequently associated with a subjective sensation of abdominal bloating, but the relation between both complaints is unknown. While the bloating sensation has a visceral origin, abdominal distention is a behavioral somatic response, involving contraction and descent of the diaphragm with protrusion of the anterior abdominal wall. Our aim was to determine whether abdominal distention influences digestive sensations. In 16 healthy women we investigated the effect of intentional abdominal distention on experimentally induced bloating sensation (by a meal overload). Participants were first taught to produce diaphragmatic contraction and visible abdominal distention. After a meal overload, sensations of bloating (0 to 10) and digestive well-being (−5 to + 5) were measured during 30-s. maneuvers alternating diaphragmatic contraction and diaphragmatic relaxation. Compared to diaphragmatic relaxation, diaphragmatic contraction was associated with diaphragmatic descent (by 21 + 3 mm; p < 0.001), objective abdominal distension (32 + 5 mm girth increase; p = 0.001), more intense sensation of bloating (7.3 + 0.4 vs. 8.0 + 0.4 score; p = 0.010) and lower digestive well-being (−0.9 + 0.5 vs. −1.9 + 0.5 score; p = 0.028). These results indicate that somatic postural tone underlying abdominal distention worsens the perception of visceral sensations (ClinicalTrials.gov ID: NCT04691882).

Prehistoric Models for Representing the Female Form

In our modern age, there are an enormous amount of forms of depiction of the female figure that have been accumulated on the basis of thousands of years of artistic experience. To make a general analysis on the all available depiction models and to put them in order would be an extremely difficult task because of the huge volume of material. Instead of using the present as a starting point we will return to the very beginning to consider the question of the first artistic manifestations of humanity and its “purest“ understanding of the Female. Our purpose is to trace which combinations of forms makes up the notion of a female figure in a period when one relies solely on subjective sensation and a primary understanding of the world and nature. Following the approach from the general to the specific, according to the appearance of the female figures we can distinguish characteristic groups with different combinations of proportions and sizes in the ratio of head, torso, hips, and legs. Each figure individually recreates the idea of the female gender, but there are enough repetitions to bring out a few basic models.

Review of Measuring Microenvironmental Changes at the Body–Seat Interface and the Relationship between Object Measurement and Subjective Evaluation

Being seated has increasingly pervaded both working and leisure lifestyles, with development of more comfortable seating surfaces dependent on feedback from subjective questionnaires and design aesthetics. As a consequence, research has become focused on how to objectively resolve factors that might underpin comfort and discomfort. This review summarizes objective methods of measuring the microenvironmental changes at the body–seat interface and examines the relationship between objective measurement and subjective sensation. From the perspective of physical parameters, pressure detection accounted for nearly two thirds (37/54) of the publications, followed by microclimatic information (temperature and relative humidity: 18/54): it is to be noted that one article included both microclimate and pressure measurements and was placed into both categories. In fact, accumulated temperature and relative humidity at the body–seat interface have similarly negative effects on prolonged sitting to that of unrelieved pressure. Another interesting finding was the correlation between objective measurement and subjective evaluation; however, the validity of this may be called into question because of the differences in experiment design between studies.