scholarly journals Folate intake, serum folate levels, and prostate cancer risk: a meta-analysis of prospective studies

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Rong Wang ◽  
Yan Zheng ◽  
Jing-Yang Huang ◽  
Ai-Qin Zhang ◽  
Yu-Hao Zhou ◽  
...  
Author(s):  
Francesca L. Crowe ◽  
Paul N. Appleby ◽  
Ruth C. Travis ◽  
Matt Barnett ◽  
Theodore M. Brasky ◽  
...  

BMJ Open ◽  
2013 ◽  
Vol 3 (5) ◽  
pp. e002280 ◽  
Author(s):  
Amanda J Carleton ◽  
John L Sievenpiper ◽  
Russell de Souza ◽  
Gail McKeown-Eyssen ◽  
David J A Jenkins

2006 ◽  
Vol 98 (11) ◽  
pp. 794-795 ◽  
Author(s):  
Gianluca Severi ◽  
Dallas R. English ◽  
John L. Hopper ◽  
Graham G. Giles

2020 ◽  
Author(s):  
Sheng Cheng ◽  
Bo Yang ◽  
Liwei Xu ◽  
Qiming Zheng ◽  
Guoqing Ding ◽  
...  

Abstract Epidemiological cohort studies investigating the association between vasectomy and prostate cancer risk have yielded inconsistent results. The aim of the present meta-analysis is to update the evidence on the association between vasectomy and prostate cancer. A comprehensively literature search of relevant studies was performed in December 2019 using PubMed. A DerSimonian and Laird random-effects model was used to calculate the summary relative risk (RR) and its 95% confidence interval (CI). A total of 15 eligible cohort studies (16 data sets) with more than four million of participants were eventually included in this meta-analysis. There was a statistically significant higher risk of prostate cancer among men who underwent vasectomy (RR: 1.09, 95% CI: 1.04–1.13) with obvious heterogeneity among included studies (P < 0.001, I2 = 64.2%). Vasectomy was also associated with the risk of advanced prostate cancer (RR: 1.07, 95% CI: 1.02–1.13), which is less likely to be affected from detection bias. In conclusion, findings from this meta-analysis of prospective studies indicate that vasectomy may be positively associated with the risk of prostate cancer. Further large prospective studies with long follow-up are warranted to verify the findings from this meta-analysis. In addition, the potential underlying molecular mechanism needed further exploration with in vitro and animal studies.


2015 ◽  
Vol 67 (3) ◽  
pp. 392-400 ◽  
Author(s):  
Huan Liu ◽  
Guang-Hui Hu ◽  
Xing-Chun Wang ◽  
Tian-Bao Huang ◽  
Liang Xu ◽  
...  

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