scholarly journals Psychoimmunological facets of psychosomatic diseases: bronchial asthma vs. rheumatoid arthritis

2006 ◽  
Vol 5 (S1) ◽  
Author(s):  
Barbara Leschinskaya ◽  
Renat Valeev ◽  
Lubomir Aftanas ◽  
Vladimir Kozlov
Keyword(s):  
Rheumatoid Arthritis ◽  
Bronchial Asthma ◽  
Psychosomatic Diseases

scholarly journals Exacerbation of Psychosomatic Disorders in Teenagehood

2019 ◽  
Vol 39 (1) ◽  
pp. 33-37
Author(s):  
O. Kuznetsova ◽  
Yu. Lanovenko
Keyword(s):  
Bronchial Asthma ◽  
Digestive System ◽  
Heart Diseases ◽  
Modern Society ◽  
Work Processes ◽  
Protective Mechanisms ◽  
Material Goods ◽  
Information Change ◽  
Psychosomatic Diseases ◽  
Flow Of Information

The article raises questions about the protective mechanisms in adolescents which shows themselves as psychosomatic diseases. The profound changes in modern society, which require a person of constant adaptation in all spheres of life: live communication is replaced by electronic, robotization of work processes, uncontrolled flow of information, change of concepts, the destruction of traditions, leading to chronic stress, exhaustion and health problems. In particular, as a result of lack of attention and lively communication, excessive demands, replacement of emotional manifestation of love with material goods in the most vulnerable part of the population - adolescents there is a feeling of needlessness, which often leads to depressive states and emotional breakdowns which cause psychological disorders. The article deals with several types of manifestations of psychosomatic diseases, such as allergies, bronchial asthma, heart diseases, diseases of the digestive system and skin, and factors that cause their appearance. The causes of psychosomatic illness are still a controversial issue due to its versatility and ambiguity. The manifestation of the disease can be affected by a variety of factors that may not cause the disease if at least one of them to be removed. Because of this ambiguity, psychosomatics are beginning to be perceived as a mystified pseudoscience. Such an attitude causes distrust to the psychologists of specialists and adherents of this teaching. Study of diseases occurs exclusively in the medical sense. What is the source of treatment in hospitals, where medication slows down the development of complications of such chronic diseases as allergies, bronchial asthma and atopic dermatitis - without treating them thoroughly since these diseases are also psychological.  

scholarly journals Strongyloides stercoralis hyperinfection in a patient with rheumatoid arthritis and bronchial asthma: a case report

2010 ◽  
Vol 9 (1) ◽  
pp. 27 ◽  
Author(s):  
Levent Altintop ◽  
Burcu Cakar ◽  
Murat Hokelek ◽  
Ahmet Bektas ◽  
Levent Yildiz ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Case Report ◽  
Bronchial Asthma ◽  
Strongyloides Stercoralis

scholarly journals DIFFERENCES IN THE ALLERGIC RESPONSES BETWEEN BRONCHIAL ASTHMA AND RHEUMATOID ARTHRITIS PATIENTS TO ADMINISTRATION OF ACTH-PREPARATION

1965 ◽  
Vol 54 (4) ◽  
pp. 311-319 ◽  
Author(s):  
Masaharu MURANAKA ◽  
Kõyõ TAKEDA ◽  
Toyohiko KIKUTANI ◽  
Hiroshi OKUMURA ◽  
Ichiro NISHIZAWA ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bronchial Asthma

Immunologic responses to an adrenocorticotropic hormone preparation in bronchial asthma and rheumatoid arthritis

1970 ◽  
Vol 46 (3) ◽  
pp. 138-149 ◽  
Author(s):  
Masaharu Muranaka ◽  
Hiroshi Okumura ◽  
Koyo Takeda ◽  
Toyohiko Kikutani ◽  
Kazuhiro Koizumi ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bronchial Asthma ◽  
Adrenocorticotropic Hormone

PITUITARY-ADRENAL FUNCTION IN PATIENTS GIVEN LONG-TERM ADRENAL STEROID THERAPY

1968 ◽  
Vol 59 (1) ◽  
pp. 76-88 ◽  
Author(s):  
Theodor Jakobson ◽  
Marcus Sundberg ◽  
Marja-Liisa Kotovirta ◽  
Leif Strandström
Keyword(s):  
Rheumatoid Arthritis ◽  
Total Dose ◽  
Bronchial Asthma ◽  
Steroid Therapy ◽  
Adrenal Function ◽  
Continuous Treatment ◽  
Adrenal Steroid ◽  
Adrenocortical Response ◽  
Adrenal Response

ABSTRACT Pituitary-adrenal function was investigated in 23 patients with rheumatoid arthritis and in 19 patients with bronchial asthma following prolonged glucocorticoid therapy. The duration of continuous treatment varied from 2 months to 15 years and the total dose of steroids from 400 mg to 54 g of prednisolone or its equivalent. After treatment had been discontinued, pituitary ACTH-reserve was estimated by means of an oral metyrapone test and adrenal response to ACTH by means of an intravenous or intramuscular ACTH-test. The pituitary ACTH-response was evaluated by determining the increment in the excretion of 11-deoxy-17-hydroxycorticosteroids during the administration of the metyrapone blocking agent and adrenal response to ACTH by the excretion of 11-oxygenated corticosteroids. The reduction of the metyrapone and ACTH responses were found to be related to the duration of prednisolone treatment as well as to the daily and total administered dose, although a marked individual variation in several instances could be observed in the degree of suppression of endogenous ACTH or corticosteroid production. Deficient metyrapone and ACTH responses were more frequently encountered in bronchial asthma than in patients with rheumatoid arthritis who had received comparable doses of glucocorticoids during similar periods. No negative metyrapone tests, however, in either group of patients were obtained for 12 months or unless the total dose of steroids administered was at least 3.5 g of prednisolone or its equivalent. Most patients who showed reduced adrenocortical response to ACTH had received large total doses of corticosteroids and the lowest total dose on which a subnormal ACTH-response was observed was 6 g. The results demonstrate that both pituitary ACTH-reserve and adrenocortical response to ACTH can be reduced by long-term adrenal steroid therapy, although the loss of pituitary ACTH-response occurs earlier during the course of treatment.

scholarly journals CO-EXPRESSION OF MEMBRANE-BOUND TUMOR NECROSIS FACTOR-α RECEPTORS IN MAJOR SUBPOPULATIONS OF IMMUNOCOMPETENT CELLS IN HEALTHY INDIVIDUALS AND PATIENTS WITH RHEUMATOID ARTHRITIS AS WELL AS BRONCHIAL ASTHMA

2021 ◽  
Vol 23 (4) ◽  
pp. 903-908
Author(s):  
Yu. V. Zhukova ◽  
A. A. Alshevskaya ◽  
F. D. Kireev ◽  
O. A. Chumasova ◽  
N. S. Shkaruba ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bronchial Asthma ◽  
Healthy Subjects ◽  
B Lymphocyte ◽  
Immune Cell ◽  
Lymphocyte Subpopulation ◽  
The Body ◽  
Membrane Bound ◽  
Factor Α

A pleiotropic cytokine TNFα is an important inflammatory mediator of a number of diseases; its biological functions are fulfilled through two different receptors, TNFR1 and TNFR2. Changes in the ratio between these types of receptors shifting the balance between the pro-apoptotic and proliferation signaling pathways play a crucial role in eliciting the cell response to TNFα. The pathological processes in the body can alter the levels of TNFR1 and TNFR2 expression on the cells involved in disease development. Therefore, this study was aimed at investigating the level of co-expression of type 1 and 2 TNFα receptors in the major subpopulations of peripheral blood cells in patients with rheumatoid arthritis (RA) and bronchial asthma (BA). The greatest changes in the percentage of cells expressing TNFR1 and TNFR2 were revealed for the B-lymphocyte subpopulation. For the T-lymphocyte subpopulation, there were some differences in the percentage of cells expressing exclusively TNFR1 in RA and BA patients compared with those in healthy subjects, as well as between the RA and BA groups. A higher percentage of double-negative monocytes was observed in patients with BA and RA compared to healthy subjects. These findings indicate that the coexpression profile of TNFR1 and TNFR2 receptors in patients with RA and BA differ within these groups as well as compared to that in healthy subjects. These immune cell populations are actively involved in the pathogenesis of both rheumatoid arthritis and bronchial asthma, so the results may indicate that these cells might show different responses to TNFα as the percentage and the number of receptors on their surface vary. 

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