scholarly journals Cough reflex sensitivity improves with speech language pathology management of refractory chronic cough

Cough ◽  
2010 ◽  
Vol 6 (1) ◽  
pp. 5 ◽  
Author(s):  
Nicole M Ryan ◽  
Anne E Vertigan ◽  
Sarah Bone ◽  
Peter G Gibson
Keyword(s):  
Chronic Cough ◽  
Speech Language Pathology ◽  
Cough Reflex Sensitivity ◽  
Cough Reflex ◽  
Language Pathology

Chronic Refractory Cough: A Case Study

2017 ◽  
Vol 2 (3) ◽  
pp. 57-62
Author(s):  
Anna Maria Siciliano
Keyword(s):  
Quality Of Life ◽  
Adult Female ◽  
Chronic Cough ◽  
Treatment Regime ◽  
Speech Language Pathology ◽  
Old Adult ◽  
Language Pathology

This paper presents a successful behavioral case study in treatment of chronic refractory cough in a 60-year-old adult female. The efficacy for speech-language pathology treating chronic cough is discussed along with description of treatment regime. Discussion focuses on therapy approaches used and the patient's report of changes in quality of life and frequency, duration, and severity reduction of her cough after treatment.

scholarly journals Is Laryngeal Hypersensitivity the Basis for Unexplained or Refractory Chronic Cough?

2021 ◽  
pp. 00793-2020
Author(s):  
Krishna M. Sundar ◽  
Amanda Carole Stark ◽  
Nan Hu ◽  
Julie Barkmeier-Kraemer
Keyword(s):  
Chronic Cough ◽  
Upper Airway ◽  
Speech Language Pathology ◽  
Appropriate Treatment ◽  
Leicester Cough Questionnaire ◽  
Language Pathology ◽  
History Of ◽  
Common Problems ◽  
Over 40 Years

BackgroundRefractory chronic cough (RCC) and unexplained chronic cough (UCC) are common problems seen in primary care and subspecialty clinics. The role of cough hypersensitivity and laryngeal dysfunction in contributing to the persistence of cough in RCC/UCC is not well recognised.MethodsData of patients with RCC and UCC evaluated in 2019 by an interdisciplinary cough clinic led by a pulmonologist and speech-language pathology team was reviewed. Patients completed validated questionnaires including the Leicester cough questionnaire (LCQ), voice handicap index (VHI) and dyspnea index questionnaire (DI) at initial encounter. Presence of cough hypersensitivity was based upon a history of allotussia and hypertussia. Laryngeal dysfunction was diagnosed in those with a history of laryngeal paresthesias, throat clearing, voice abnormalities, upper airway dyspnoea and documentation of functional or anatomic laryngeal abnormalities on nasoendoscopy.FindingsOf the 60 UCC/RCC patients analysed, 75% of patients were female and 85% were over 40 years of age. Cough hypersensitivity was documented in all patients and multiple cough triggers occurred in 75% of patients. 95%, 50% and 25% of patients reported laryngeal paresthesias, voice abnormalities and upper airway dyspnoea, respectively. Significant associations between LCQ and VHI and DI scores occurred when adjusting for age, gender, ethnicity and body mass index. Laryngeal functional abnormalities were documented on 44/60 patients on nasoendoscopy.InterpretationHypertussia, allotussia and laryngeal dysfunction are common in patients with RCC and UCC. Evaluation of UCC and RCC can delineate laryngeal hypersensitivity and allows appropriate treatment to be directed at this phenotype.

scholarly journals Evaluation and Management Outcomes and Burdens in Patients with Refractory Chronic Cough Referred for Behavioral Cough Suppression Therapy

2021 ◽  
Author(s):  
Laurie Slovarp ◽  
Marie Jette ◽  
Amanda Gillespie ◽  
Jane Reynolds ◽  
Julie Barkmeier-Kraemer
Keyword(s):  
Chronic Cough ◽  
Cost Effective ◽  
Speech Language Pathology ◽  
Symptom Pattern ◽  
Leicester Cough Questionnaire ◽  
Language Pathology ◽  
Clinically Significant ◽  
Initial Survey ◽  
Efficient Option

Abstract Purpose: The purpose of this study was to investigate the typical symptoms and medical management characteristics of adult patients with refractory chronic cough (RCC) who are referred to speech-language pathology (SLP) for behavioral cough suppression therapy (BCST) in order to estimate cost-effectiveness and efficiency of current practice patterns for this population.Methods: One hundred fifty-nine (159) patients with RCC referred for BCST were surveyed. Patients completed an initial survey at BCST onset related to symptom pattern and prior treatment, including the Leicester Cough Questionnaire (LCQ). Every 4-6 weeks patients completed follow-up surveys to assess their response to BCST.Results: Mean age was 58 years (83% women). The majority of participants reported their cough began two or more years prior to BCST. Approximately half reported seeing four or more physicians (49%) and being prescribed four or more medications (55%) prior to BCST. Medications targeting post-nasal drip (71%), reflux (70%), asthma (56%), and allergies (56%) were most commonly prescribed. BCST resulted in a clinically significant improvement in 113 (70.1%) participants. The mean change in LCQ for those who improved with BCST was 6.61. Over half (58%) reported they were quite satisfied to completely satisfied with their treatment response. The average time from enrollment to study completion was 64 days. Conclusion: The results of this study suggest early intervention with BCST may be a more cost-effective and efficient option for patients with RCC.

scholarly journals Chronic cough: how do cough reflex sensitivity and subjective assessments correlate with objective cough counts during ambulatory monitoring?

Thorax ◽  
2007 ◽  
Vol 62 (4) ◽  
pp. 329-334 ◽  
Author(s):  
S. Clare Decalmer ◽  
D. Webster ◽  
A. Alice Kelsall ◽  
K. McGuinness ◽  
A. Arthur Woodcock ◽  
...  
Keyword(s):  
Chronic Cough ◽  
Ambulatory Monitoring ◽  
Cough Reflex Sensitivity ◽  
Cough Reflex ◽  
Subjective Assessments

Efficacy of Speech-language Pathology Therapy in Chronic Cough: Systematic Review With Meta-analysis

2021 ◽  
Author(s):  
Vanessa Veis Ribeiro ◽  
Maria Christina Bussamara Casmerides ◽  
Zélia Maria Conceição da Silva Reis ◽  
Ícaro Vinícius de Santana ◽  
Rodrigo Dornelas do Carmo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Chronic Cough ◽  
Meta Analysis ◽  
Speech Language Pathology ◽  
Language Pathology

Cough reflex sensitivity and airway inflammation in patients with chronic cough due to non-acid gastro-oesophageal reflux

Respirology ◽  
2011 ◽  
Vol 16 (4) ◽  
pp. 645-652 ◽  
Author(s):  
ZHIHONG QIU ◽  
LI YU ◽  
SHUCHANG XU ◽  
BO LIU ◽  
TING ZHAO ◽  
...  
Keyword(s):  
Airway Inflammation ◽  
Chronic Cough ◽  
Oesophageal Reflux ◽  
Cough Reflex Sensitivity ◽  
Cough Reflex

Cough Hypersensitivity and Suppression in Chronic Obstructive Pulmonary Disease

2020 ◽  
pp. 2003569
Author(s):  
Peter S P Cho ◽  
Hannah V Fletcher ◽  
Irem S Patel ◽  
Richard D Turner ◽  
Caroline J Jolley ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Chronic Cough ◽  
Healthy Subjects ◽  
Geometric Mean ◽  
Challenge Test ◽  
Chronic Obstructive ◽  
Cough Reflex Sensitivity ◽  
Obstructive Pulmonary Disease ◽  
Cough Reflex ◽  
Healthy Participants

Cough reflex hypersensitivity (CRH) and impaired cough suppression are features of chronic refractory cough (CRC). Little is known about cough suppression and CRH in cough associated with chronic obstructive pulmonary disease (COPD). This study investigated the ability of participants with COPD to suppress cough during a cough challenge test in comparison to participants with CRC and healthy subjects. This study also investigated whether CRH is associated with chronic cough in COPD.Participants with COPD (n=27), CRC (n=11), and healthy subjects (n=13) underwent capsaicin challenge test with and without attempts to self-suppress cough in a randomised order over 2 visits, 5 days apart. For participants with COPD, the presence of self-reported chronic cough was documented, and objective 24-h cough frequency was measured.Amongst participants with COPD, those with chronic cough (n=16) demonstrated heightened cough reflex sensitivity (CRS) compared to those without chronic cough (n=11); geometric mean (sd) capsaicin dose thresholds for 5 coughs (C5) 3.36 (6.88) versus 44.50 (5.90) µmol·L−1 respectively (p=0.003). Participants with CRC also had heightened CRS compared to healthy participants; geometric mean (sd) C5 3.86 (5.13) versus 45.89 (3.95) µmol·L−1 respectively (p<0.001). Participants with COPD were able to suppress capsaicin-evoked cough, regardless of the presence or absence of chronic cough; geometric mean (sd) capsaicin dose thresholds for 5 coughs without self-suppression attempts (C5) and with (CS5) were 3.36 (6.88) versus 12.80 (8.33) µmol·L−1 (p<0.001) and 44.50 (5.90) versus 183.2 (6.37) µmol·L−1 (p=0.006) respectively. This was also the case for healthy participants (C5 versus CS5: 45.89 (3.95) versus 254.40 (3.78) µmol·L−1, p=0.033), but not those with CRC, who were unable to suppress capsaicin-evoked cough (C5 versus CS5: 3.86 (5.13) versus 3.34 (5.04) µmol·L−1, p=0.922). C5 and CS5 were associated with objective 24-h cough frequency in participants with COPD; ρ=−0.430, p=0.036 and ρ=−0.420, p=0.041 respectively.Participants with COPD-chronic cough and CRC both have heightened cough reflex sensitivity but in contrast, only participants with CRC were unable to suppress capsaicin evoked cough. This suggests differing mechanisms of cough between participants with COPD and CRC, and the need for disease specific approaches to its management.

Sign in / Sign up

Export Citation Format

Share Document