scholarly journals Sequential occurrence of thrombotic thrombocytopenic purpura, essential thrombocythemia, and idiopathic thrombocytopenic purpura in a 42-year-old African-American woman: a case report and review of the literature

2012 ◽  
Vol 6 (1) ◽  
Author(s):  
Mirna H Farhat ◽  
Philip Kuriakose ◽  
Michael Jawad ◽  
Amr Hanbali
2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Hafiz Rizwan Talib Hashmi ◽  
Gilda Diaz-Fuentes ◽  
Preeti Jadhav ◽  
Misbahuddin Khaja

A 49-year-old African American woman was admitted to our hospital with abdominal pain, nausea, vomiting, lethargy, and confusion. She was receiving ciprofloxacin for a urinary-tract infection prior to admission. Laboratory examination revealed anemia, thrombocytopenia, elevated lactate dehydrogenase, and serum creatinine. Peripheral smear showed numerous schistocytes, and the patient was diagnosed with thrombotic thrombocytopenic purpura (TTP). Ciprofloxacin was identified as the offending agent. The patient received treatment with steroids and plasmapheresis, which led to rapid clinical recovery. This is the first case to our knowledge of successfully treated ciprofloxacin-induced TTP; previously reported cases had fulminant outcomes. Quinolones are an important part of the antibiotic armamentarium, and this case can raise awareness of the association between quinolones and TTP. A high index of suspicion for detection and early and aggressive management are vitally important for a successful outcome.


F1000Research ◽  
2014 ◽  
Vol 3 ◽  
pp. 297 ◽  
Author(s):  
Rohit Kumar Gudepu ◽  
Mohtashim A. Qureshi ◽  
Ihtesham A. Qureshi ◽  
Lakshman Rao

Moyamoya is a rare idiopathic progressive vaso-occlusive disease characterized by irreversible condition of main blood vessels to the brain as they enter into the skull. We present a case of 36 year old African American female presenting to the Out Patient Clinic with headache which were on and off for 4-6 months and did not relieve on routine medical therapy. It was associated with weakness on right side for last few days. The patient was investigated with CT Angiogram, diagnosed as Moyamoya disease and operated. She has been followed up for the last 5 years and the patient has not complained of any headaches or focal neurological symptoms.


2018 ◽  
Vol 5 (3) ◽  
pp. 17
Author(s):  
Jerad A.K. Harris ◽  
Mark Shane Gillispie ◽  
Claribel Solario ◽  
Melody L. Tran ◽  
Rogelio Pinon-Gutierrez ◽  
...  

We describe a 47-year-old African American woman affected by a rapidly progressing thromboangiitis associated with high serum levels of lipoprotein(a) (Lp(a)).


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