scholarly journals Case Report: A case report of Moyamoya disease in a 36 year old African American woman

F1000Research ◽  
2014 ◽  
Vol 3 ◽  
pp. 297 ◽  
Author(s):  
Rohit Kumar Gudepu ◽  
Mohtashim A. Qureshi ◽  
Ihtesham A. Qureshi ◽  
Lakshman Rao

Moyamoya is a rare idiopathic progressive vaso-occlusive disease characterized by irreversible condition of main blood vessels to the brain as they enter into the skull. We present a case of 36 year old African American female presenting to the Out Patient Clinic with headache which were on and off for 4-6 months and did not relieve on routine medical therapy. It was associated with weakness on right side for last few days. The patient was investigated with CT Angiogram, diagnosed as Moyamoya disease and operated. She has been followed up for the last 5 years and the patient has not complained of any headaches or focal neurological symptoms.

2018 ◽  
Vol 5 (3) ◽  
pp. 17
Author(s):  
Jerad A.K. Harris ◽  
Mark Shane Gillispie ◽  
Claribel Solario ◽  
Melody L. Tran ◽  
Rogelio Pinon-Gutierrez ◽  
...  

We describe a 47-year-old African American woman affected by a rapidly progressing thromboangiitis associated with high serum levels of lipoprotein(a) (Lp(a)).


2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S110-S110
Author(s):  
Hanadi El Achi ◽  
William Glass ◽  
Miriam Velazquez ◽  
Zhihong Hu

Abstract The patient is a 62-year-old African American female with medical history of Plummer Vinson syndrome and CT scan in 2014 showing lymphadenopathy of the porta hepatis. Needle core biopsy of enlarged lymph nodes revealed sheets of polytypic plasma cells with no aberrant B or T cells or granulomas or hyaline-like depositions identified. The findings were suspicious for unicentric Castleman disease. In 2019, the patient presented with chronic fatigue without other systemic symptoms. Contrast CT revealed persistent retroperitoneal lymphadenopathy and calcified granulomas in the liver, spleen, and lung. Excision of portal and celiac nodes showed preserved nodal architecture with mild mantle zone expansion and marked hyaline-like deposition in the follicles. Sheets of mature plasma cells and focally increased vasculatures were seen in the interfollicular areas. Focally frequent nonnecrotizing granulomas were noted. Occasional giant cells and rare asteroid bodies were identified in the granulomas. Immunohistochemistry stain workup revealed normal distribution of the B and T lymphocytes. CD138 stain highlighted marked increased plasma cells and HHV8 was negative. Immunofluorescence microscopy for kappa and lambda did not show monoclonality; IgA was positive in <10% of plasma cells; special stain for Congo red and serum amyloid associated protein (SSA) IHC stain were strongly positive in the follicles. The overall findings are consistent with reactive lymphadenopathy with interfollicular polytypic plasmacytosis, noncaseating granuloma formation, and reactive amyloidosis. The features of mantle zone hyperplasia and polytypic plasmacytosis are suggestive of HHV8-negative/idiopathic unicentric Castleman disease. This case possibly represents an example of concurrent amyloidosis, sarcoidosis, and idiopathic unicentric Castleman disease. Given that SSA was recently reported to have a pathogenic role in granulomatous inflammation of sarcoidosis through sustained inflammatory reaction, the possibility of increased SSA triggering sarcoidoisis in this patient can be considered. However, the exact pathogenesis of these concurrent findings needs further investigation and clarification.


2017 ◽  
Vol 26 (4) ◽  
pp. 353-355 ◽  
Author(s):  
Osama Elfituri ◽  
Snehal Sonawane ◽  
Haoliang Xu ◽  
Michael A. Warso ◽  
Elizabeth Wiley

Mammary sclerosing lobular hyperplasia is an uncommon benign fibroproliferative lesion of adolescent and young women, often of African American heritage with an incidence of ~3%. Patients generally complain of a palpable, painless, or slightly tender and well-defined lump in breast. Very rarely, this lesion may be bilateral and diffuse. The definitive diagnosis of sclerosing lobular hyperplasia requires histopathologic evaluation. Here, we describe a case of diffuse sclerosing lobular hyperplasia in a 29-year-old African American woman that required bilateral mastectomy and recurred bilaterally requiring second resections. This appears to be the first report of this phenomenon.


Author(s):  
Pamela E. Scott-Johnson ◽  
Pamela M. Leggett-Robinson

Women of color have historically been underrepresented across the sciences. Neuroscience is no exception. Unfortunately, few studies have examined or shed light on how the dual presence of race and gender affects the educational and professional experiences of African American women in science. This chapter will reflect upon the journey of being an African American woman of science (psychology and neuroscience) in the academy and the blessings not abundantly clear. Through a critical lens, recognizing how the journey would have been more difficult without the supportive network of individual and the critical importance of Historically Black Colleges and Universities. Understanding the context of the times and the need to develop networks that facilitate success of future generations of African American female scholars is crucial.


2018 ◽  
Vol 29 (1) ◽  
pp. 41-47 ◽  
Author(s):  
Stella Ioannou ◽  
Maciej Henneberg

Congenital syphilis is a disease recognized for interfering with odontogenesis, producing specificdental characteristics including Hutchinson’s incisor, Moon’s molar, Fournier’s molar and mulberry molar,while its past treatments including mercury are known to affect amelogenesis. Supernumerary teeth, mainly associatedwith syndromes, are not commonly found in cases of congenital syphilis. A rare case of congenitalsyphilis in an individual (P000707) treated with mercury and a mandibular left fourth molar with normal morphologyis presented.Materials and Methods: During a systematic examination of 28 skeletons with treponemal disease at the Smithsonianmuseum in Washington, DC, a supernumerary mandibular distomolar in one individual (P000707) wasrevealed.Results: P000707 was an African American female, 26 years of age. Dentition showed severe enamel hypoplasiaof the maxillary and mandibular incisors, left canine, and upper first molars, consistent with the effects of treatmentof congenital syphilis by mercurial compounds. Crown of the left mandibular distomolar has typical molarmorphology but is smaller in size than other permanent molars. Arrangement of grooves resembles the +4 pattern,but is complex due to crenulation. Oblique x-ray revealed that the fourth molar had one root with a pulpchamber extending towards the apex, suggesting taurodontism. No other distomolar teeth were present.Conclusions: Congenital syphilis and treatment containing mercury may not influence the development of supernumeraryteeth due to: (1) the age at which the development of the fourth molar takes place, (2) the stage ofthe infection at the time of development and (3) the age at which treatments containing mercury are administeredto patients with congenital syphilis.


Sign in / Sign up

Export Citation Format

Share Document