scholarly journals #Hyperbaric oxygen therapy (1.5 ATA) in treating sports related TBI/CTE: two case reports

2011 ◽  
Vol 1 (1) ◽  
pp. 17 ◽  
Author(s):  
Kenneth P Stoller
2021 ◽  
Vol 8 ◽  
Author(s):  
Diogo Alpuim Costa ◽  
Pedro Modas Daniel ◽  
João Vieira Branco

Pneumatosis cystoides intestinalis (PCI) is characterized by gas-filled cysts within gastrointestinal tract wall from esophagus to rectum, with preferential involvement of large and small intestine. PCI is rare with an estimated incidence of 0.03 to 0–2% in general population. PCI can be distinguished into idiopathic (15%) or secondary (85%) and the clinical picture ranges from completely asymptomatic to life-threatening intraabdominal complications. Although etiology of PCI appears to be multifactorial, the exact pathophysiology is poorly understood and two main theories have been proposed (mechanical and bacterial). Over the last decades, an enormous therapeutic armamentarium was considered in PCI's management, including hyperbaric oxygen therapy (HBOT). Treatment comprises conservative treatment in mild cases to surgery in highly symptomatic and complicated PCI. In the late 70s, HBOT started to be used in selected cases of PCI not responding to conservative measures. Since then, several case reports, case series, and reviews have been published in the literature with variable outcomes. The overall response rate and complete response were 92.1% (n = 82/89) and 65.2% (n = 58/89), respectively, with a median follow-up of 7 months. Furthermore, HBOT is extremely safe, with few reported complications in the literature when used for PCI. Nevertheless, a randomized, controlled, and double-blind clinical trial is unlikely to occur given the rarity of PCI, logistical issues of HBOT, and methodological considerations related to adequate blinding with a sham-controlled group. HBOT in combination with personalized diet and antibiotics may be beneficial for moderate to severe PCI in patients with no indication for emergency exploratory laparotomy. The purpose of this article is to synthesize the existing data, analyse results of previous studies, identify gaps in knowledge, and discuss PCI' management, including the proposal of an algorithm, with a special focus on HBOT.


Author(s):  
Shahram Oliaei ◽  
SeyedAhmad SeyedAlinaghi ◽  
Mohammad Mehrtak ◽  
Amirali Karimi ◽  
Tayebeh Noori ◽  
...  

Abstract Background Oxygenation serves as a cornerstone in the treatment of COVID-19, and several methods have been extensively studied so far. Herein, we aimed to systematically review the studies discussing hyperbaric oxygen therapy (HBOT) to examine its reported efficacy and adverse events in patients with COVID-19. Methods We systematically searched and retrieved the relevant articles using keywords on the online databases, including PubMed, Scopus, Embase, Web of Science, and Cochrane databases up to April 11th, 2021. The retrieved records underwent a two-step title/abstract and full-text screening process, and the eligible papers were identified. National Institutes of health (NIH) quality assessment tool was used for this study. This study was registered in the International Prospective Register of Systematic Reviews (PROSPERO) with ID CRD42021269821. Results Eight articles from three countries were included. All the included studies had good and fair quality scores, with no poor studies included in this systematic review (Good: n = 5, Fair: n = 3). Studies were divided into clinical trials and case reports/series. Most of the studies used HBOT less than 1.5–2 absolute atmospheres (ATA) for 90 min sessions and thereafter sessions were decreased to 60 min. Trials demonstrated most of the patients recovered after receiving HBOT, and blood oxygen saturation increased after several sessions of HBOT. Conclusion Overall, HBOT seems to be a safe and effective oxygenation method in patients with COVID-19. However, there is limited knowledge and evidence regarding the effects and mechanism of HBOT in COVID-19 treatment, and further evaluations require extensive well-designed studies.


2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Chilyatiz Zahroh

Gangrenous wounds is one of the chronic complications of diabetes that most feared by every diabetic patient (Tjokroprawiro, 2007). Gangrenous wounds is a condition that begins from the tissue hypoxia where oxygen is reduced, it will affect the activity of vascular and cellular networks, which results in tissue damage (Guyton, 2006). TOHB (Hyperbaric Oxygen Therapy) or Hyperbaric Oxygen Therapy or HBO therapy (Hyperbaric Oxygen) is a way to increase tissue oxygen levels, by reducing the swelling caused by vasoconstriction of blood vessels. At the same time, TOHB also increases oxygen levels in the blood (Neubauer, 1998). Oxygen is expected to penetrate through to the peripheral tissues are deprived of oxygen, so that the supply of nutrients and oxygen are met, so that the network can do metabolism and function (Smeltzer, 2002). Review was conducted at 10 research/article. Search strategy articles by using two ways: manual and online libraries. This search is getting 113 articles, but the total articles reviewed were the 10 articles. 1 studies are case reports and 9 research is experimental research with 5 studies using random techniques. TOHB with adequate doses can have a positive effect on wound healing and reduce the risk of amputation. TOHB beneficial to improve peripheral perfusion and decrease the incidence of major amputation. However, there has been no research on the psychology of the patient.


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