scholarly journals Accelerated hand bone mineral density loss is associated with progressive joint damage in hands and feet in recent-onset rheumatoid arthritis

2010 ◽  
Vol 12 (3) ◽  
pp. R96 ◽  
Author(s):  
Melek Güler-Yüksel ◽  
Naomi B Klarenbeek ◽  
Yvonne PM Goekoop-Ruiterman ◽  
Jeska K de Vries-Bouwstra ◽  
Sjoerd M van der Kooij ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Joint Damage ◽  
Mineral Density ◽  
Bone Mineral Density Loss ◽  
Recent Onset ◽  
Hands And Feet ◽  
Progressive Joint Damage

scholarly journals Early Metacarpal Bone Mineral Density Loss Using Digital X-Ray Radiogrammetry and 3-Tesla Wrist MRI in Established Rheumatoid Arthritis: A Longitudinal One-Year Observational Study

Arthritis ◽  
2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Anshul Rastogi ◽  
Jakob Algulin ◽  
Pamela Mangat ◽  
Adrian K. P. Lim ◽  
Keshthra Satchithananda ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Joint Damage ◽  
Metacarpal Bone ◽  
X Rays ◽  
Mineral Density ◽  
Bone Mineral Density Loss ◽  
X Ray ◽  
One Year

Objectives. Early change in rheumatoid arthritis (RA) is characterised by periarticular osteopenia. We investigated the relationship of early metacarpal digital X-ray radiogrammetry bone mineral density (DXR-BMD) change rate (RC-BMD, mg/cm2/month) to longitudinal changes in hand and feet radiographic and wrist MRI scores over 1 year. Materials and Methods. 10 RA patients completed the study and had wrist 3T-MRI and hand and feet X-rays at various time points over 1 year. MRI was scored by RAMRIS, X-ray was done by van der Heijde modified Sharp scoring, and RC-BMD was analysed using dxr-online. Results. There was good correlation amongst the two scorers for MRI measures and ICC for erosions: 0.984, BME: 0.943, and synovitis: 0.657. Strong relationships were observed between RC-BMD at 12-week and 1-year change in wrist marrow oedema (BME) (r=0.78, P=0.035) but not with erosion, synovitis, or radiographic scores. Conclusion. Early RC-BMD correlates with 1-year wrist BME change, which is a known predictor of future erosion and joint damage. However, in our pilot study, early RC-BMD did not show relationships to MRI erosion or radiographic changes over 1 year. This may reflect a slower kinetic in the appearance of MRI/radiographic erosions, generating the hypothesis that RC-BMD may be a more sensitive and early structural prognostic marker in RA follow-up.

Changes in bone mineral density in patients with recent onset, active rheumatoid arthritis

2008 ◽  
Vol 67 (6) ◽  
pp. 823-828 ◽  
Author(s):  
M Guler-Yuksel ◽  
J Bijsterbosch ◽  
Y P M Goekoop-Ruiterman ◽  
J K de Vries-Bouwstra ◽  
H M J Hulsmans ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Active Rheumatoid Arthritis ◽  
Mineral Density ◽  
Recent Onset

SAT0097 Changes In Bone Mineral Density in Patients with Recent-Onset Rheumatoid Arthritis

2013 ◽  
Vol 72 (Suppl 3) ◽  
pp. A612.2-A612
Author(s):  
H. Heo ◽  
Y. J. Kim ◽  
B. S. Koo ◽  
M.-W. So ◽  
W. J. Seo ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Mineral Density ◽  
Recent Onset

scholarly journals Bone Mineral Density Changes in Patients with Recent-Onset Rheumatoid Arthritis

2011 ◽  
Vol 4 ◽  
pp. CMAMD.S7773 ◽  
Author(s):  
Eman A. Hafez ◽  
Howaida E. Mansour ◽  
Sherin H. Hamza ◽  
Sherine George Moftah ◽  
Takwa Badr Younes ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Dual Energy ◽  
Mineral Density ◽  
X Ray ◽  
Recent Onset ◽  
Das 28 ◽  
Radiological Damage ◽  
The Difference

Background Osteoporosis and related fragility fractures are one of the most common complications seen in patients with rheumatoid arthritis (RA) and dramatically affect quality of life. Objective To evaluate changes in bone mineral density in patients with recent onset rheumatoid arthritis (< 1 year) and its correlation if any with a modified DAS-28 score and simple erosion narrowing score (SENS). Methods This study included 30 patients with recent-onset rheumatoid arthritis fulfilling the new American College of Rheumatology/European League Against Rheumatism diagnostic criteria for rheumatoid arthritis and 20 healthy volunteers as controls. All were subjected to a complete blood count, erythrocyte sedimentation rate, C-reactive protein, liver function tests, renal function tests, rheumatoid factor, and plain x-rays of the hands and feet. Dual-energy x-ray absorptiometry DEXA was used to measure bone mineral density (BMD) of the left proximal femur, lumbar spine (L1–L4), and lower distal radius at the time of recruitment. Results In the RA patients, 13.3% had osteoporosis, 50% had osteopenia, and 36.7% had normal BMD. The most common site of osteoporosis was the lumbar spine (four patients, 13.3%) followed by the femur (two patients, 6.6%), and forearm (only one patient, 3.3%). There was a significantly higher percentage of osteoporosis among RA males than females and the difference was statistically significant ( P = 0.009). Osteoporosis was more common in patients treated with corticosteroids and disease modifying antirheumatic drugs (DMARDs) than in patients treated with only nonsteroidal anti-inflammatory drugs ( P = 0.004). Higher disease activity (DAS-28) was found in RA patients with osteoporosis compared to RA patients with normal BMD or osteopenia, but the difference was not statistically significant. Osteoporotic RA patients were found to have a higher SENS score for radiological damage than nonosteoporotic ones. Conclusion BMD changes do occur in patients with early RA, and are not necessarily correlated with disease activity (DAS-28). However, a significant negative correlation was found between BMD and the score of radiological damage (SENS). Dual energy x-ray absorptiometry is an important investigation to assess BMD in early RA patients.

scholarly journals Rheumatoid arthritis in tight disease control is no longer risk of bone mineral density loss

2020 ◽  
Vol 6 (2) ◽  
pp. 75-81 ◽  
Author(s):  
Ichiro Yoshii ◽  
Tatsumi Chijiwa ◽  
Naoya Sawada
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Mineral Density ◽  
Disease Control ◽  
Bone Mineral ◽  
Mineral Density ◽  
Bone Mineral Density Loss

scholarly journals Bone mineral density in patients with recent onset rheumatoid arthritis: influence of disease activity and functional capacity.

1993 ◽  
Vol 52 (1) ◽  
pp. 21-26 ◽  
Author(s):  
R F Laan ◽  
W C Buijs ◽  
A L Verbeek ◽  
M P Draad ◽  
F H Corstens ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Mineral Density ◽  
Disease Activity ◽  
Bone Mineral ◽  
Functional Capacity ◽  
Mineral Density ◽  
Recent Onset

The characteristics of bone mineral density, erosive and destructive changes in joints of hands and feet, vertebral deformities in patients with rheumatoid arthritis

2014 ◽  
Author(s):  
Elena Petrova ◽  
Irina Dydykina ◽  
Aleksandr Smirnov ◽  
Marina Podvorotova ◽  
Elena Taskina ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Mineral Density ◽  
Vertebral Deformities ◽  
Hands And Feet

The characteristics of bone mineral density, erosive and destructive changes in joints of hands and feet, vertebral deformities in patients with rheumatoid arthritis

2014 ◽  
Author(s):  
Elena Petrova ◽  
Irina Dydykina ◽  
Aleksandr Smirnov ◽  
Marina Podvorotova ◽  
Elena Taskina ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Mineral Density ◽  
Vertebral Deformities ◽  
Hands And Feet

FRI0517 Early metacarpal bone mineral density loss is predictive for radiologic joint damage progression after 1 year in patients with early arthritis

2013 ◽  
Vol 72 (Suppl 3) ◽  
pp. A549.2-A549 ◽  
Author(s):  
K. V. C. Wevers-De Boer ◽  
L. Heimans ◽  
K. Visser ◽  
J. Kälvesten ◽  
R. Goekoop ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Joint Damage ◽  
Metacarpal Bone ◽  
Early Arthritis ◽  
Mineral Density ◽  
Bone Mineral Density Loss ◽  
Damage Progression
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