scholarly journals Extravascular lung water and the pulmonary vascular permeability index may improve the definition of ARDS

Critical Care ◽  
2013 ◽  
Vol 17 (1) ◽  
pp. 108 ◽  
Author(s):  
Azriel Perel
Keyword(s):  
Vascular Permeability ◽  
Extravascular Lung Water ◽  
Permeability Index ◽  
Lung Water ◽  
Pulmonary Vascular Permeability ◽  
Pulmonary Vascular Permeability Index ◽  
Definition Of

scholarly journals Increased extravascular lung water index (EVLWI) reflects rapid inflammatory oedema and mortality in COVID-19 associated ARDS

2020 ◽  
Author(s):  
Sebastian Rasch ◽  
Paul Schmidle ◽  
Senguel Sancak ◽  
Alexander Herner ◽  
Christina Huberle ◽  
...  
Keyword(s):  
Pulmonary Oedema ◽  
Extravascular Lung Water ◽  
Transpulmonary Thermodilution ◽  
Control Group ◽  
Intensive Care Treatment ◽  
Lung Water ◽  
Pulmonary Vascular Permeability ◽  
Pulmonary Vascular Permeability Index ◽  
Extravascular Lung Water Index ◽  
Water Index

OBJECTIVE: Nearly 5 % of the patients with COVID-19 develop an acute respiratory distress syndrome (ARDS). Extravascular lung water index (EVLWI) is a marker of pulmonary oedema which is associated with mortality in ARDS. In this study we evaluate whether EVLWI is higher in patients with COVID-19 associated ARDS as compared to controls and whether EVLWI has the potential to monitor disease progression. METHODS: From the day of intubation, EVLWI, cardiac function were monitored by transpulmonary thermodilution in n=25 patients with COVID-19 and compared to a control group of 49 non-COVID-19 ARDS-patients. RESULTS: EVLWI in COVID-19-patients was noticeably elevated and significantly higher than in the control group (17 (11-38) vs. 11 (6-26) mL/kg; p<0.001). High pulmonary vascular permeability index values (2.9 (1.0-5.2) versus 1.9 (1.0-5.2); p=0.003) suggest inflammatory oedema. By contrast, the cardiac parameters SVI, GEF and GEDVI were comparable. High EVLWI values were associated with viral persistence, prolonged intensive care treatment and mortality (23.2±6.7% vs. 30.3±6.0%, p=0.025). CONCLUSIONS: Compared to the control group, COVID-19 results in markedly elevated EVLWI-values in patients with ARDS. EVLWI reflects a non-cardiogenic pulmonary oedema in COVID-19 associated ARDS and could serve as parameter to monitor ARDS progression.

1455: PULMONARY VASCULAR PERMEABILITY INDEX COULD NOT PREDICT SYSTEMIC ORGAN FAILURE IN SEPTIC PATIENTS

2018 ◽  
Vol 46 (1) ◽  
pp. 711-711
Author(s):  
Kazuaki Shigemitsu ◽  
Hiroshi Rinka ◽  
Kenichiro Morisawa ◽  
Shigeki Fujitani ◽  
Yasuhiko Taira
Keyword(s):  
Organ Failure ◽  
Vascular Permeability ◽  
Permeability Index ◽  
Pulmonary Vascular Permeability ◽  
Pulmonary Vascular Permeability Index
Sign in / Sign up

Export Citation Format

Share Document