The efficacy of nasal cavity lavage with a physiological saline solution in prevention of recurrent acute otitis media: a pilot randomised controlled study

AbstractObjective:This study aimed to compare outcomes for mastoidotympanoplasty and for tympanoplasty alone in cases of quiescent, tubotympanic, chronic, suppurative otitis media.Study design:Single-blinded, randomised, controlled study within a tertiary referral hospital.Methods:Sixty-eight cases were randomly allocated into two groups. In group one, 35 ears underwent type one tympanoplasty along with cortical mastoidectomy. In group two, 33 ears underwent type one tympanoplasty alone. Outcome measures were as follows: perforation closure and graft uptake, hearing improvement, disease eradication, and post-operative complications.Results:There were no statistically significant differences in hearing improvement, tympanic perforation closure, graft uptake or disease eradication, comparing the two groups at three and six months post-operatively.Conclusion:Mastoidotympanoplasty was not found to be superior to tympanoplasty alone over a short term follow-up period. Hence, it may not be necessary to undertake routine mastoid exploration at this stage of disease.

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The Effects of Dexmedetomidine and Fentanyl on Emergence Characteristics after Adenoidectomy in Children

Anaesthesia and Intensive Care ◽

10.1177/0310057x0903700405 ◽

2009 ◽

Vol 37 (4) ◽

pp. 571-576 ◽

Cited By ~ 39

Author(s):

F. Erdil ◽

S. Demirbilek ◽

Z. Begec ◽

E. Ozturk ◽

M. H. Ulger ◽

...

Keyword(s):

Saline Solution ◽

Controlled Study ◽

Physical Status ◽

Early Recovery ◽

Anaesthetic Agents ◽

Randomised Controlled Study ◽

Eye Opening ◽

Randomised Controlled ◽

Study Intervention ◽

Group D

This randomised controlled study evaluated the effects of fentanyl and dexmedetomidine on emergence characteristics of children having adenoidectomy and anaesthetised with sevoflurane. Ninety children, two to seven years of age and ASA physical status I, were studied. Children were randomly assigned to one of three groups of 30 children, with the study intervention injection given intravenously after intubation. Children in Group F received fentanyl 2.5 μg.kg−1 children in Group D received dexmedetomidine 0.5 μg.kg−1 and children in Group C received saline solution. Anaesthesia was induced with 50% N2O and 8% sevoflurane in O2 by mask and atracurium 0.6 mg.kg−1 was administered for tracheal intubation. All children received paracetamol 40 mg/kg rectally one hour preoperatively and dexamethasone 0.5 mg.kg−1 intravenously. The time to extubation was shorter in Group D than Group F. The eye-opening time was longer in Group F (16.1∓5.3 minutes) than in Groups C (12.0∓4.2 minutes) and D (12.7∓3.2 minutes). The proportion of pain-free children in early recovery was significantly higher in Groups D (47%) and F (43%) than Group C (13%) (P <0.05). The proportion of children with agitation scores >3 was lower in Groups D 17% (5/30) and F 13% (4130) than in Group C 47% (14/30) (P <0.05). Fentanyl 2.5 μg.kg−1 and dexmedetomidine 0.5 μg.kg−1 had similar haemodynamic effects and emergence characteristics. Fentanyl has been safely used in children for many years. Further studies of dexmedetomidine safety and its interaction with other anaesthetic agents are required before recommending its routine use during general anaesthesia in children.

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Adenoidectomy versus chemoprophylaxis and placebo for recurrent acute otitis media in children aged under 2 years: randomised controlled trial

BMJ ◽

10.1136/bmj.37972.678345.0d ◽

2004 ◽

Vol 328 (7438) ◽

pp. 487 ◽

Cited By ~ 43

Author(s):

Petri Koivunen ◽

Matti Uhari ◽

Jukka Luotonen ◽

Aila Kristo ◽

Risto Raski ◽

...

Keyword(s):

Randomised Controlled Trial ◽

Otitis Media ◽

Controlled Trial ◽

Acute Otitis Media ◽

Recurrent Acute Otitis Media ◽

Randomised Controlled

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Co-amoxiclav in recurrent acute otitis media: placebo controlled study.

BMJ ◽

10.1136/bmj.303.6815.1450 ◽

1991 ◽

Vol 303 (6815) ◽

pp. 1450-1452 ◽

Cited By ~ 51

Author(s):

C L Appelman ◽

J Q Claessen ◽

F W Touw-Otten ◽

G J Hordijk ◽

R A de Melker

Keyword(s):

Otitis Media ◽

Acute Otitis Media ◽

Controlled Study ◽

Recurrent Acute Otitis Media

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Sem Studies of Co-Cr-Mo Surgical Implant Alloy Corrosion Behavior

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100055448 ◽

1982 ◽

Vol 40 ◽

pp. 520-521

Author(s):

Ann Chidester Van Orden ◽

John L. Chidester ◽

Anna C. Fraker ◽

Pei Sung

Keyword(s):

Electron Microscopy ◽

Corrosion Behavior ◽

Anodic Polarization ◽

Saline Solution ◽

Saturated Calomel Electrode ◽

Physiological Saline ◽

X Ray ◽

Physiological Saline Solution ◽

Scanning Electron

The influence of small variations in the composition on the corrosion behavior of Co-Cr-Mo alloys has been studied using scanning electron microscopy (SEM), energy dispersive x-ray analysis (EDX), and electrochemical measurements. SEM and EDX data were correlated with data from in vitro corrosion measurements involving repassivation and also potentiostatic anodic polarization measurements. Specimens studied included the four alloys shown in Table 1. Corrosion tests were conducted in Hanks' physiological saline solution which has a pH of 7.4 and was held at a temperature of 37°C. Specimens were mechanically polished to a surface finish with 0.05 µm A1203, then exposed to the solution and anodically polarized at a rate of 0.006 v/min. All voltages were measured vs. the saturated calomel electrode (s.c.e.).. Specimens had breakdown potentials near 0.47V vs. s.c.e.

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Erythrophagocytosis by Entamoeba histolytica.- Ultrastructural Study

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100094036 ◽

1972 ◽

Vol 30 ◽

pp. 156-157 ◽

Cited By ~ 1

Author(s):

Norberto Treviño ◽

Alfredo Feria-Velasco ◽

I. Ruiz de Chávez

Keyword(s):

Electron Microscopy ◽

Light Microscopy ◽

Entamoeba Histolytica ◽

Ultrastructural Study ◽

Saline Solution ◽

Physiological Saline ◽

Ultrastructural Level ◽

Hot Plate ◽

Physiological Saline Solution ◽

Axenic Conditions

Although erythrophagocytosis by various species of Entamoeba is a well known phenomenon this has not yet been studied in detail at the ultrastructural level. The present work deals with the description of the incorporation process of erythrocytes by trophozoites of E. histolytica. For this study, trophozoites of E. histolytica, HK-9:NIH strain cultured in axenic conditions and washed human erythrocytes were placed on a hot plate at 37°C in physiological saline solution. After 5 minutes, 2.5% glutarldehyde was added and the samples were processed according to conventional techniques for electron microscopy.Based upon light microscopy studies on living trophozoites in contact with erythrocytes, it seems that erythrophagocytosis only takes place in one pole of the parasite.

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