scholarly journals AXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas

BMC Cancer ◽  
2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Caitlin D. May ◽  
Jeannine Garnett ◽  
XiaoYan Ma ◽  
Sharon M. Landers ◽  
Davis R. Ingram ◽  
...  
2016 ◽  
Vol 22 (10) ◽  
pp. 1305-1311 ◽  
Author(s):  
Juan Camilo Jurado-Coronel ◽  
Marco Avila-Rodriguez ◽  
Francisco Capani ◽  
Janneth Gonzalez ◽  
Valentina Echeverria Moran ◽  
...  

2020 ◽  
Vol 26 ◽  
Author(s):  
Yujie Shen ◽  
Yexiang Lin ◽  
Kai Liu ◽  
Jinlan Chen ◽  
Juanjuan Zhong ◽  
...  

Background: A number of studies have proposed that lncRNA XIST plays a role in the development and chemosensitivity of NSCLC. Besides, XIST may become a potential therapeutic target for NSCLC patients. The aim of this review is to reveal the biological functions and exact mechanisms of XIST in NSCLC. Methods: In this review, relevant researches involving in the relationship between XIST and NSCLC are collected through systematic retrieval of PubMed Results: XIST is an oncogene in NSCLC and is abnormally upregulated in NSCLC tissues. Considerable evidence has shown that XIST exerts a critical role in the proliferation, invasion, migration, apoptosis and chemosensitivity of NSCLC cells. XIST mainly functions as a ceRNA in NSCLC process, while XIST also functions at transcriptional levels. Conclusion: LncRNA XIST has potential to become a novel biomolecular marker of NSCLC and a therapeutic target for NSCLC.


2016 ◽  
Vol 18 (1) ◽  
pp. 27-34 ◽  
Author(s):  
Gerardo Botti ◽  
Laura Marra ◽  
Maria Malzone ◽  
Annamaria Anniciello ◽  
Chiara Botti ◽  
...  

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