scholarly journals Psychometric validation of the Moroccan version of the EORTC QLQ-C30 in colorectal Cancer patients: cross-sectional study and systematic literature review

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yacir El Alami ◽  
Hajar Essangri ◽  
Mohammed Anass Majbar ◽  
Saber Boutayeb ◽  
Said Benamr ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Discriminant Validity ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Related Quality ◽  
Eortc Qlq C30 ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients

Abstract Background Health-related quality of life is mainly impacted by colorectal cancer which justified the major importance addressed to the development and validation of assessment questionnaires. We aimed to assess the validity and reliability of the Moroccan Arabic Dialectal version of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Core Questionnaire (QLQ-C30) in patients with colorectal cancer. Methods We conducted a cross-sectional study using the Moroccan version of the EORTC QLQ-C30 on colorectal cancer patients from the National Oncology Institute of Rabat, in the period from February 2015 to June 2017. The QLQ-C30 was administered to 120 patients. Statistical analysis included reliability, convergent, and discriminant validity as well as known-groups comparisons. Results In total, 120 patients with colorectal cancer were included in the study with 38 (32%) patients diagnosed with colon cancers. Eighty-two patients (68%) had rectal cancer, among which 29 (24%) patients with a stoma. The mean age of diagnosis was 54 years (+/− 13.3). The reliability and validity of the Arabic dialectal Moroccan version of the EORTC QLQ-C30 were satisfactory. [Cronbach’s alpha (α =0.74)]. All items accomplished the criteria for convergent and discriminant validity except for question number 5, which did not complete the minimum required correlation with its own scale (physical functioning). Patients with rectal cancer presented with bad Global health status and quality of life (GHS/QOL), emotional functioning as well as higher fatigue symptoms compared to patients with colon cancer. The difference between patients with and without stoma was significant for diarrhea and financial difficulty. Conclusions The Moroccan Arabic Dialectal version of the QLQ-C30 is a valid and reliable measure of health-related quality of life (HRQOL) in patients with colorectal cancer.

scholarly journals QUALITY OF LIFE AMONG COLORECTAL CANCER PATIENTS AT THAI NGUYEN ONCOLOGY CENTER

2021 ◽  
Vol 62 (4) ◽  
Author(s):  
Nguyen To Quynh Chau ◽  
Nguyen Manh Tuan ◽  
Nguyen Thanh Nhai ◽  
Nguyen Thi Ngan ◽  
Tran Bao Ngoc
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Cancer Patients ◽  
Cross Sectional Study ◽  
Functional Score ◽  
Cross Sectional ◽  
European Organization ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients

Aim: To describe quality life’s colorectal cancer patients who are being treated at Thai Nguyenoncology center from June 2020 to August 2020.Objects and method: The descriptive cross- sectional study was conducted over 68 patientsdiagnosed with colorectal cancer by face to face interview using the European Organization forResearch and Treatment of Cancer (EORTC) QLQ-C30 and the EORTC QLQ-CR29.Results: Mean of overall health score was 51,96±18,78; mean of functional score was 21,49±12,42(1,71–47,06). In functional sector, social function was scored lowest. In symptomatic scale, appetiteloss was scored highest (47,06).Conclusion: Quality of life of colorectal cancer patients was medium level. Highest scores wereobserved for appetite loss and fatigue. To improve quality life’s patients, medical staffs need to keepenhancing symptoms and function for patients during treatment.

scholarly journals Measuring health-related quality of life in colorectal cancer patients: systematic review of measurement properties of the EORTC QLQ-CR29

2019 ◽  
Vol 27 (7) ◽  
pp. 2395-2412
Author(s):  
Anja van der Hout ◽  
Koen I. Neijenhuijs ◽  
Femke Jansen ◽  
Cornelia F. van Uden-Kraan ◽  
Neil K. Aaronson ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Systematic Review ◽  
Measurement Properties ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients

Chemotherapy-Induced Neuropathy and Its Association With Quality of Life Among 2- to 11-Year Colorectal Cancer Survivors: Results From the Population-Based PROFILES Registry

2013 ◽  
Vol 31 (21) ◽  
pp. 2699-2707 ◽  
Author(s):  
Floortje Mols ◽  
Tonneke Beijers ◽  
Valery Lemmens ◽  
Corina J. van den Hurk ◽  
Gerard Vreugdenhil ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Population Based ◽  
Negative Influence ◽  
Life Questionnaire ◽  
Burning Pain ◽  
Related Quality ◽  
Eortc Qlq C30 ◽  
Eortc Qlq

Purpose To gain insight into the prevalence and severity of chemotherapy-induced neuropathy and its influence on health-related quality of life (HRQOL) in a population-based sample of colorectal cancer (CRC) survivors 2 to 11 years after diagnosis. Methods All alive individuals diagnosed with CRC between 2000 and 2009 as registered by the Dutch population-based Eindhoven Cancer Registry were eligible for participation. Eighty-three percent (n = 1,643) of patients filled out the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ) C30 and the EORTC QLQ Chemotherapy-Induced Peripheral Neuropathy 20. Results The five neuropathy subscale–related symptoms that bothered patients with CRC the most during the past week were erectile problems (42% of men), trouble hearing (11%), trouble opening jars or bottles (11%), tingling toes/feet (10%), and trouble walking stairs or standing up (9%). Additionally, patients who received oxaliplatin more often reported tingling (29% v 8%; P = .001), numbness (17% v 5%; P = .005), and aching or burning pain (13% v 6%; P = .03) in toes/feet compared with those not treated with chemotherapy. They also more often reported tingling toes/feet (29% v 14%; P = .0127) compared with those treated with chemotherapy without oxaliplatin. Those with many neuropathy symptoms (eg, upper 10%) reported statistically significant and clinically relevant worse HRQOL scores on all EORTC QLQ-C30 subscales (all P < .01). Conclusion Two to 11 years after diagnosis of CRC, neuropathy-related symptoms are still reported, especially sensory symptoms in the lower extremities among those treated with oxaliplatin. Because neuropathy symptoms have a negative influence on HRQOL, these should be screened for and alleviated. Future studies should focus on prevention and relief of chemotherapy-induced neuropathy.

Is there a difference in quality of life, comparing summer and winter, in patients who have undergone total laryngectomy?

2007 ◽  
Vol 122 (9) ◽  
pp. 967-971
Author(s):  
F C Van Wyk ◽  
F Vaz ◽  
M Harries ◽  
J Weighill
Keyword(s):  
Quality Of Life ◽  
Total Laryngectomy ◽  
Cross Sectional Study ◽  
Short Term ◽  
Cross Sectional ◽  
European Organization ◽  
Eortc Qlq C30 ◽  
Eortc Qlq ◽  
The Impact

AbstractIntroduction:Several studies have implied that patients' quality of life stabilises six months after undergoing total laryngectomy. However, these studies may well have overlooked persistent short term variations in patients' quality of life. The aim of this study was to assess the impact of seasonal change (i.e. summervswinter) on the quality of life of patients following total laryngectomy.Methods:A prospective, cross-sectional study of recurrence-free laryngectomy patients was performed, using the European Organization for Research and Treatment of Cancer (version three) QLQ-C30 questionnaires (EORTC QLQ-C30), during January 2004 (i.e. winter), August 2004 (summer) and January 2005 (winter).Results:Thirty-six patients were entered into the study. The response rate was 70.3 per cent. Patient's time elapsed since surgery varied from six months to 12 years. In all questionnaire domains, responses seemed remarkably consistent over time.Conclusion:No statistically significant differences were found between summer and winter scores in all the domains analysed by the EORTC QLQ-C30.

scholarly journals Health Related Quality of Life among Blood Cancer Patients in Pakistan: A Cross Sectional Survey

2021 ◽  
Vol 58 ◽  
pp. 004695802110252
Author(s):  
Madeeha Malik ◽  
Ifrah Rizwan ◽  
Azhar Hussain
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Blood Cancer ◽  
Related Quality ◽  
Eortc Qlq C30 ◽  
Health Related ◽  
Eortc Qlq

The importance of health-related quality of life and its determinants including physical, emotional, and functional domains has long been recognized among blood cancer patients in the developed world but this concept is still in infancy in developing countries, including Pakistan. The objective of the study was to assess health related quality of life among blood cancer patients. A descriptive cross-sectional study design was used. A pre-validated questionnaire that is EORTC-QLQ-C30 was self-administered to a sample of 400 blood cancer patients selected using convenience sampling technique. After data collection, data was cleaned, coded, and entered in SPSS. Descriptive statistics comprising of frequency and percentages were calculated. Non-parametric tests Kruskal Wallis and Mann Whitney tests ( P ≤ .05) were performed to find out the differences among different variables. The results highlighted that lowest scores for EORTC-QLQ-C30 were observed in the domain of emotional functioning (3.38, ±35.790), followed by cognitive function (4.56, ±30.368) whereas highest scores were observed in the domain of physical functioning (40.92, ±35.484). Significant difference ( P ≤ .05) was observed among different domains of health-related quality of life of blood cancer patients treated in different sectors, provinces, setting, gender, and with different comorbidities. The present study concluded that blood cancer patients had poor health related quality of life in Pakistan. Emotional functioning and cognitive function were the most compromised health related quality of life domains among blood cancer patients. Females having blood cancer, those patients treated in private sector healthcare facilities, patients residing in tribal and rural setting had relatively better health related quality of life. No appropriate psychosocial care program for the blood cancer patients are available in Pakistan.

scholarly journals Quality of life, distress, and posttraumatic growth 5 years after colorectal cancer diagnosis according to history of inpatient rehabilitation

2021 ◽  
Author(s):  
Sophie Scherer-Trame ◽  
Lina Jansen ◽  
Lena Koch-Gallenkamp ◽  
Volker Arndt ◽  
Jenny Chang-Claude ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Posttraumatic Growth ◽  
Statistical Significance ◽  
Least Square ◽  
Related Quality ◽  
Eortc Qlq C30 ◽  
Eortc Qlq ◽  
Population Controls

Abstract Purpose In Germany, almost every other colorectal cancer (CRC) patient undergoes inpatient cancer rehabilitation (ICR), but research on long-term outcomes is sparse. We aimed to assess health-related quality of life (HRQOL), distress, and posttraumatic growth among former rehabilitants and non-rehabilitants as well as respective differences and to estimate disease-related quality of life deficits in both groups. Methods HRQOL (EORTC-QLQ-C30/CR29), distress (QSC-R10), and posttraumatic growth (PTGI) were assessed according to past ICR in patients 5-year post-CRC-diagnosis in the German DACHS study. Least square mean differences in HRQOL scores and elevated distress levels (QSC-R10 > 14 points) by ICR were estimated by confounder-adjusted linear and logistic regression, respectively. Differences in PTGI scales were tested for statistical significance. EORTC-QLQ-C30 reference scores from population controls were accessed from the LinDE study to estimate disease-related deficits in both treatment groups. Results 49% of the included 1906 CRC survivors had undergone ICR. Rehabilitants reported lower HRQOL scores than non-rehabilitants in several dimensions of the EORTC-QLQ-C30/CR29. Differences were pronounced among younger survivors (< 70 years). In younger survivors, past ICR also predicted elevated distress. However, rehabilitants showed higher posttraumatic growth. When compared to 934 population controls, non-rehabilitants and older rehabilitants reported HRQOL scores (EORTC-QLQ-C30) similar to controls except higher levels of bowel dysfunctions, whereas younger rehabilitants experienced deficits regarding most scales (13/15). Conclusion Our findings suggest a high disease burden 5 years after diagnosis in particular among younger CRC survivors who had undergone ICR. Observed HRQOL deficits are possibly linked to the initial indication for ICR and rehabilitants may benefit from effective follow-up concepts after ICR.

scholarly journals Quality of life and project of cancer patients in Colombia, a strategy for the creation of a public policy

2019 ◽  
Author(s):  
Martin Romero-Prada ◽  
Rafael Chaves ◽  
Maria Victoria Victoria Ocampo ◽  
Duvan Gallo ◽  
Lina Maria Huerfano
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Cross Sectional Study ◽  
Health Condition ◽  
Health State ◽  
Cross Sectional ◽  
Eortc Qlq C30 ◽  
Eortc Qlq ◽  
Patient’S Perception

Abstract Background: The quality of life related to health and the outcomes perceived by cancer patients, is a concept that allows knowing the patient's perception of their health situation and the conditions associated with these. This study is part of the PROCAN strategy, originally devised as response to deficiencies in state policies aimed to assess the health condition of cancer patients and the difficulties which arise while posing multidimensional interventions designed to better a patient’s quality of life. Methods: A cross-sectional study was developed in a representative sample of cancer patients in Colombia, in which the standardized generalized instrument EQ5D3L and a specific instrument called EORTC QLQ-C30 were applied. The characterization data of the population were analyzed by descriptive statistics. Results: The defined scales were applied to 360 patients. The global health state of the EORTC QLQ-C30 was of 66.05, which compared with the control scale EQ5D3L was of 0.70 and with the analog visual scale of 69.79. EORTC QLQ-C30 were applied The emotional and social functions were the most affected. And from a symptoms’ perspective, financial difficulties created the greatest impact (52.8), followed by insomnia and fatigue, all of which were above pain. Conclusions: Therefore, what this study intents to achieve is the promotion of the use of measurements of a cancer patient’s quality of life with the purpose of, in the first place, developing process that would mitigate the damage to the most affected dimensions with the focused pathology, and the development of follow-up actions within the Colombian social security services that would aid the evaluation of proposed strategies after the original assessment of a cancer patient’s quality of life.

scholarly journals The Association between ADL Ability and Quality of Life among People with Advanced Cancer

2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Mette Falk Brekke ◽  
Karen la Cour ◽  
Åse Brandt ◽  
Hanne Peoples ◽  
Eva Ejlersen Wæhrens
Keyword(s):  
Quality Of Life ◽  
Advanced Cancer ◽  
Cross Sectional Study ◽  
Life Questionnaire ◽  
Occupational Science ◽  
Cross Sectional ◽  
European Organization ◽  
Eortc Qlq C30 ◽  
Eortc Qlq

Background. Occupational therapy and occupational science are founded on the theoretical core assumption that occupation and quality of life (QoL) are closely related. However, such theoretical core assumptions must be supported through empirically based research. Objective. To investigate the association between QoL and occupation, here self-reported and observed ADL abilities as a part of occupation, among people with advanced cancer, including determining whether self-reported or observed ADL ability had the stronger association with QoL. Methods. The study was nested in a cross-sectional study. The association between ADL ability and QoL among 108 people with advanced cancer was investigated using the ADL Interview (ADL-I), the Assessment of Motor and Process Skills (AMPS), and the European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC-QLQ-C30). Results and Conclusions. Results showed that high observed ADL motor ability was associated with high QoL. In contrast, observed ADL process ability and self-reported ADL ability were not significantly associated with QoL. Oppositely expected, observed ADL ability had a stronger association with QoL than self-reported ADL ability. Thereby, the study to some extent contributes knowledge confirming the theoretical core assumptions about the relation between occupation, here performance of ADL, and QoL.

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