Case report of anti-N-methyl-D-aspartate receptor encephalitis in a middle-aged woman with a long history of major depressive disorder

Background Paragangliomas are rare neuroendocrine tumors, especially in the bladder. Although many paragangliomas are non-functional, functioning paragangliomas present with many non-specific signs and symptoms, such as hypertension and headache, complicating their diagnosis. Here, we report a case of micturition-induced severe headache associated with a bladder paraganglioma. Case description: This report describes a severe headache disorder triggered by micturition and associated with a bladder paraganglioma in a middle-aged woman. Her pain occurred consistently after micturition, beginning from the left side of the nose and gradually extended to the forehead and the parietal and occipital regions. The headaches lasted 5–10 min. Removal of the paraganglioma completely eliminated the patient’s pain syndrome. Conclusion This case elucidates the association between micturition-triggered headaches and bladder paragangliomas. The presence of a post-micturition severe headache should suggest the possibility of a bladder paraganglioma.

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270 A Case Report on a Primary Hepatic Yolk Sac Tumor in a Middle-Aged Woman—A Challenging Diagnosis

American Journal of Clinical Pathology ◽

10.1093/ajcp/aqx123.269 ◽

2018 ◽

Vol 149 (suppl_1) ◽

pp. S115-S115

Author(s):

Andrey Prilutskiy ◽

Josenia Tan ◽

Qing Zhao

Keyword(s):

Case Report ◽

Yolk Sac ◽

Yolk Sac Tumor ◽

Middle Aged ◽

Aged Woman ◽

Middle Aged Woman

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Psychiatric shades of grey: mirtazapine-induced hair discoloration and hair loss

Irish Journal of Psychological Medicine ◽

10.1017/ipm.2015.71 ◽

2016 ◽

Vol 33 (3) ◽

pp. 175-178 ◽

Cited By ~ 1

Author(s):

M. Osman ◽

M. D. McCauley

Keyword(s):

Major Depressive Disorder ◽

Case Report ◽

Adverse Effects ◽

Depressive Disorder ◽

Hair Loss ◽

Temporal Relationship ◽

Relevant Literature ◽

Major Depressive ◽

Hair Colour ◽

Medical Reason

IntroductionMirtazapine is indicated in the treatment of major depressive disorder particularly in selective serotonin re-uptake inhibitors resistance. Its effect on hair loss is rare with no previous documented effect on hair colour.MethodReview of relevant literature and description of a case report of a 54-year-old male patient who developed alopecia and hair discoloration after initiation of mirtazapine treatment.ResultsUpon cessation of mirtazapine treatment full restoration of hair colour and regrowth of hair was attained within 10 weeks.DiscussionThere was clear temporal relationship between experiencing hair loss and commencing mirtazapine treatment. No other more likely medical reason to explain such experience was established. A noticeable restoration of the hair colour occurred following mirtazapine cessation.ConclusionMirtazapine is associated with hair discoloration and hair loss. The possibility of such distressing adverse effects needs to be conveyed to patients by clinicians and to be further explored by researchers.

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