scholarly journals Human infection and environmental contamination with Avian Influenza A (H7N9) Virus in Zhejiang Province, China: risk trend across the three waves of infection

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Fan He ◽  
En-Fu Chen ◽  
Fu-Dong Li ◽  
Xin-Yi Wang ◽  
Xiao-Xiao Wang ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Environmental Contamination ◽  
Influenza A ◽  
Human Infection ◽  
Zhejiang Province ◽  
H7n9 Virus

Identification of meteorological factors associated with human infection with avian influenza A H7N9 virus in Zhejiang Province, China

2018 ◽  
Vol 644 ◽  
pp. 696-709 ◽  
Author(s):  
Steven Yuk-Fai Lau ◽  
Xiaoxiao Wang ◽  
Maggie Wang ◽  
Shelan Liu ◽  
Benny Chung-Ying Zee ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A ◽  
Meteorological Factors ◽  
Human Infection ◽  
Zhejiang Province ◽  
H7n9 Virus ◽  
Factors Associated

scholarly journals Emergence of human avian influenza A(H7N9) virus infections in Wenshan City in Southwest China, 2017

2019 ◽  
Author(s):  
Li Jiang ◽  
Xiaonan Zhao ◽  
Wen Xu ◽  
Xuehua Zhou ◽  
Chunrui Luo ◽  
...  
Keyword(s):  
Phylogenetic Analysis ◽  
Avian Influenza ◽  
Influenza A ◽  
Human Infection ◽  
Viral Gene ◽  
H7n9 Virus ◽  
Genetic Sequencing ◽  
Live Poultry ◽  
Virus Spreading ◽  
Live Poultry Markets

Abstract Background: The emergence of human infection with avian influenza A(H7N9) virus was reported in Wenshan City, southwestern China in 2017. The study describes the epidemiological and virological features of the outbreak and discusses the origin of the infection. Methods: Poultry exposure and timelines of key events for each patient were collected. Samples derived from the patients, their close contacts, and environments were tested for influenza A(H7N9) virus by real-time reverse transcription polymerase chain reaction. Genetic sequencing and phylogenetic analysis were also conducted. Results: Five patients were reported in the outbreak. An epidemiological investigation showed that all patients had been exposed at live poultry markets. Virus isolates from these patients had low pathogenicity in avian species. Both epidemiological investigations of chicken sources and phylogenetic analysis of viral gene sequences indicated that the source of infection was from Guangxi Province. Conclusions: The transmission route spanned a long geographical region, with virus spreading from east to west. Chickens were an important carrier in the H7N9 virus spreading from Guangxi to Wenshan. Hygienic management of live poultry markets and virological screening of chickens transported across regions should be reinforced to limit the spread of H7N9 virus.

scholarly journals Epidemiologic characterization of 30 confirmed cases of human infection with avian influenza A(H7N9) virus in Hangzhou, China

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Hua Ding ◽  
Li Xie ◽  
Zhou Sun ◽  
Qing-Jun Kao ◽  
Ren-Jie Huang ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A ◽  
Human Infection ◽  
H7n9 Virus

Epidemiology of human infections with avian influenza A(H7N9) virus in the two waves before and after October 2013 in Zhejiang province, China

2014 ◽  
Vol 143 (9) ◽  
pp. 1839-1845 ◽  
Author(s):  
X. Y. WANG ◽  
C. L. CHAI ◽  
F. D. LI ◽  
F. HE ◽  
Z. YU ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A ◽  
Case Fatality ◽  
Zhejiang Province ◽  
H7n9 Virus ◽  
Virus Infections ◽  
Before And After ◽  
Live Poultry ◽  
Second Wave ◽  
Live Poultry Markets

SUMMARYWe compared the epidemiological and clinical features of avian influenza A(H7N9) virus infections in the population in Zhejiang province, China, between March and April 2013 (first wave) and October 2013 and February 2014 (second wave). No statistical difference was found for age, sex, occupation, presence of underlying conditions, exposure history, white blood cell count, lymphocyte percentage and illness timeline and duration (all P > 0·05). The virus spread to 30 new counties compared to the first wave. The case-fatality rate was 22% in the first wave and 42% in the second (P = 0·023). Of those infected, 66% in the first wave and 62% in the second wave had underlying conditions. The proportion of those exposed to live poultry markets were 80% and 66%, respectively. We recommend permanent closure of live poultry markets and reformation of poultry supply and sales.

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