scholarly journals The giant resectable carcinoma of gall bladder—a case report

BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Lovenish Bains ◽  
Haraesh Maranna ◽  
Pawan Lal ◽  
Ronal Kori ◽  
Daljit Kaur ◽  
...  

Abstract Background Gall bladder cancer (GBC) is the fifth most common malignancy in the gastrointestinal system and the most common malignancy of the biliary system. GBC is a very aggressive malignancy having a 5 year survival rate of 19%. Giant Gall Bladder (GGB) is an uncommon condition that can result from cholelithiasis or chronic cholecystitis and rarely with malignancy. Case report A 65 year old lady presented with vague abdominal pain for 12 years and right abdominal lump of size 20 × 8 cms was found on examination. CT scan showed a circumferentially irregularly thickened wall (2.5 cm) of gall bladder indicative of malignancy. Per-operatively a GB of size 24 × 9 cm was noted and patient underwent radical cholecystectomy. It was surprise to find such a giant malignant GB with preserved planes. Histopathology, it was well differentiated adenocarcinoma of gall bladder of Stage II (T2a N0 M0). Discussion It is known that mucocoele of GB can attain large size, however chronic cholecystitis will lead to a shrunken gall bladder rather than an enlarged one. A malignant GB of such size and resectable is rare without any lymph node involvement or liver infiltration. Few cases of giant benign gall bladder have been reported in literature, however this appears to be the largest resectable gall bladder carcinoma reported till date as per indexed literature. Conclusion Giant GB is an uncommon finding. They are mostly benign, however malignant cases can occur. Radiological findings may suggest features of malignancy and define extent of disease. Prognosis depends on stage of disease and resectability, irrespective of size.

2020 ◽  
Author(s):  
Lovenish Bains ◽  
Haraesh Maranna ◽  
Pawan Lal ◽  
Ronal Kori ◽  
Daljit Kaur ◽  
...  

Abstract Background: Gall bladder cancer (GBC) is the fifth most common malignancy in the gastrointestinal system and the most common malignancy of the biliary system. GBC is a very aggressive malignancy having a 5 year survival rate of 19%. Giant Gall Bladder (GGB) is an uncommon condition that can result from cholelithiasis or chronic cholecystitis and rarely with malignancy.Case report: A 65 year old lady presented with vague abdominal pain for 12 years and right abdominal lump of size 20x8 cms was found on examination. CT scan showed a circumferentially irregularly thickened wall (2.5cm) of gall bladder indicative of malignancy. Per-operatively a GB of size 24 x 9 cms was noted and patient underwent radical cholecystectomy. It was surprise to find such a giant malignant GB with preserved planes. Histopathology, it was well differentiated adenocarcinoma of gall bladder of Stage II (T2a N0 M0). Discussion: It is known that mucocoele of GB can attain large size, however chronic cholecystitis will lead to a shrunken gall bladder rather than an enlarged one. A malignant GB of such size and resectable is rare without any lymph node involvement or liver infiltration. Few cases of giant benign gall bladder have been reported in literature, however this appears to be the largest resectable gall bladder carcinoma reported till date as per indexed literature.Conclusion: Giant GB is an uncommon finding. They are mostly benign, however malignant cases can occur. Radiological findings may suggest features of malignancy and define extent of disease. Prognosis depends on stage of disease and resectability, irrespective of size.


2017 ◽  
Vol 11 (1) ◽  
pp. 413-419 ◽  
Author(s):  
Narjiss Akerzoul ◽  
Saliha Chbicheb ◽  
Wafaa El Wady

Introduction: Odontomas are considered as benign tumors of odontogenic tissue origin and are more over non-aggressive. They can also be categorized as hamartomas and are a result of developmental malformation of odontogenic tissues. As the name suggests, they are composed of mature tooth substances. They possess limited and slow growth potential and are well differentiated. They can be ectodermal, mesodermal or mixed in origin. Mixed variety may be further divided into compound or complex depending upon their radio-graphical resemblance to the tooth. Compound odontomes are reported to be twice more common than complex odontomes. Among them, complex odontomes are asymptomatic unless they cause bony expansion of the jaws. Case Report: This paper aims to report and discuss a case of complex odontoma with unusually large size leading to gross facial asymmetry. Further this paper will highlight the important information the general dental practitioner must possess to diagnose such lesions at an early stage. Conclusion: Odontomas are benign odontogenic tumors with unusually large size leading to gross facial asymmetry. The general dental practitioners must possess the knowledge and important information to diagnose such lesions at an early stage.


1992 ◽  
Vol 14 (4) ◽  
pp. 356-360 ◽  
Author(s):  
Annarosaria De Chiara ◽  
Jan M. Van Tornout ◽  
Yoichi Hachitanda ◽  
Jorge A. Ortega ◽  
Hiroyuki Shimada

2005 ◽  
Vol 446 (5) ◽  
pp. 546-554 ◽  
Author(s):  
Ömer Uluoğlu ◽  
Nalan Akyürek ◽  
Aytuğ Üner ◽  
Uğur Coşkun ◽  
Ayşegul Özdemir ◽  
...  

2006 ◽  
Vol 7 (1) ◽  
pp. 81-84 ◽  
Author(s):  
Lesley Taylor ◽  
Mohamad Aziz ◽  
Paula Klein ◽  
Amitabha Mazumder ◽  
Sundar Jagannath ◽  
...  

2017 ◽  
Vol 37 (8) ◽  
pp. 1096-1098 ◽  
Author(s):  
Hana Saffar ◽  
Fatemeh Nili ◽  
Mahrooz Malek ◽  
Behnaz Jahanbin ◽  
Akram Ghahghaei Nezamabadi

Medwave ◽  
2021 ◽  
Vol 21 (10) ◽  
pp. e8493-e8493
Author(s):  
Roberto Ignacio Olmos Borzone ◽  
Jorge Andrés López Ruiz-Esquide ◽  
Francisco Domínguez Covarrubias ◽  
José Miguel Domínguez Ruiz-Tagle

Papillary thyroid cancer is the most common endocrine malignancy, and due to its favorable prognosis, the extent of surgery has been a matter of debate. About 10% of these tumors are located in the thyroid isthmus, with no specific management in current guidelines. In the last decades, isthmusectomy has been proposed as a therapeutic option for isthmic papillary thyroid carcinoma, although there is no consensus on its management. We present two cases of patients from our institution with solitary isthmic papillary thyroid carcinoma without clinical macroscopic extrathyroidal extension or clinical-radiological lymph node involvement who were treated with isthmusectomy without prophylactic lymph node dissection. Neither of them had any postoperative complications. Both had an intermediate risk of recurrence due to aggressive variants. None of them had signs of recurrence during follow-up. We intend to show that isthmusectomy seems to be an effective and safe surgical alternative in selected patients through these cases.


2018 ◽  
Vol 5 (5) ◽  
pp. 1978
Author(s):  
Sowmya Murugesan ◽  
Chandru R. ◽  
Ramya Ramakrishnan ◽  
Rajiv Raj ◽  
Kishore Kumar G.

Porcelain gall bladder is a rare entity and a morphological variant of chronic cholecystitis. Dystrophic calcification along with inflammatory scarring of the wall gives the porcelain nature to the gall bladder. Patients are mostly asymptomatic and incidentally diagnosed on X-ray, ultrasound or CT abdomen. In the early stages they can be a surprise as only a histopathological diagnosis. Prophylactic cholecystectomy is recommended in view of high risk of malignancy.


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