scholarly journals Spontaneous regression of quiescent gestational trophoblastic disease after pregnancy: a case report

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Yoshiyuki Okada ◽  
Shingo Miyamoto ◽  
Takashi Mimura ◽  
Tetsuya Ishikawa ◽  
Akihiko Sekizawa ◽  
...  
Keyword(s):  
Case Report ◽  
Spontaneous Regression ◽  
Gestational Trophoblastic Disease ◽  
Trophoblastic Disease

Successful use of anti-retroviral therapy in combination with cytotoxic chemotherapy for persistent molar pregnancy: A case report

2003 ◽  
Vol 13 (2) ◽  
pp. 246-248
Author(s):  
M. Moodley ◽  
J. Moodley
Keyword(s):  
Case Report ◽  
Antiretroviral Therapy ◽  
Young Women ◽  
Ethical Dilemmas ◽  
Gestational Trophoblastic Disease ◽  
Cytotoxic Chemotherapy ◽  
Molar Pregnancy ◽  
Trophoblastic Disease ◽  
Response To Chemotherapy

Due to the HIV pandemic, the chances of finding gynecological malignancies in HIV-infected women are increased. This poses management and ethical dilemmas as the treatment for such malignancies are likely to further decrease their immunity. Gestational trophoblastic disease occurs predominantly among young women and has excellent response to chemotherapy. However, such therapy is not possible if their immunity (CD4 counts) is markedly depressed. The patient described presented with persistent molar pregnancy and had low CD4 count. She was given antiretroviral therapy and once the CD4 count had risen to acceptable levels cytotoxic chemotherapy was administered. She received a total of 13 cycles of chemotherapy with no significant untoward effects. After a 6-month follow-up period the patient was well with a negative serum βHCG level and CD4 count above 200. We conclude that HIV-infected women with gestational trophoblastic disease may be safely treated with cytotoxic chemotherapy provided anti-retroviral therapy is concurrently administered to boost immunity.

scholarly journals Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review

Open Medicine ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. 1038-1042
Author(s):  
Yan Wan ◽  
Guoqing Jiang ◽  
Ying Jin ◽  
Zengping Hao
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Hydatidiform Mole ◽  
Gestational Trophoblastic Disease ◽  
Optimal Treatment ◽  
Perimenopausal Woman ◽  
Trophoblastic Disease ◽  
Reproductive Females

Abstract Gestational trophoblastic disease (GTD) commonly occurs in reproductive females, but is extremely rare in perimenopausal females. In this study, we reported a case of hydatidiform mole in a 48-year-old perimenopausal female admitted due to a giant uterine mass of 28 weeks’ gestational size. The serum human chorionic gonadotropin (HCG) level ranged from 944 to 1,286 mIU/mL before treatments. The signs of preeclampsia and hyperthyroidism were relatively prominent. Hysterectomy was performed and chemotherapy was scheduled when the serum HCG level remained at a plateau, about 528 mIU/mL. The symptoms of preeclampsia and hyperthyroidism were relieved after treatment. Accordingly, we concluded that GTD could occur in perimenopausal woman and hysterectomy usually is the optimal treatment.

scholarly journals A rare presentation of invasive mole with an arterio-venous malformation: a case report

2020 ◽  
Vol 9 (5) ◽  
pp. 2180
Author(s):  
Atmajit Singh Dhillon ◽  
Vartika Pathak
Keyword(s):  
Case Report ◽  
Venous Malformation ◽  
Hydatidiform Mole ◽  
Emergency Admission ◽  
Gestational Trophoblastic Disease ◽  
Severe Bleeding ◽  
Rare Presentation ◽  
Trophoblastic Disease ◽  
Common Etiology ◽  
Invasive Mole

Gestational trophoblastic disease comprises of various pathologies with hydatid form mole bring a common etiology. Emergency admissions of patients of gestational trophoblastic disease is very rare. Here we present a case report of an emergency admission of patient with hydatidiform mole and severe bleeding and then was managed for the same during the course of hospital stay.

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