scholarly journals Imaging findings of uterine adenosarcoma with sarcomatous overgrowth: two case reports, emphasizing restricted diffusion on diffusion weighted imaging

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Go Nakai ◽  
Hiroki Matsutani ◽  
Takashi Yamada ◽  
Masahide Ohmichi ◽  
Kazuhiro Yamamoto ◽  
...  
Keyword(s):  
Signal Intensity ◽  
Diffusion Weighted Imaging ◽  
High Signal Intensity ◽  
High Signal ◽  
Cervical Canal ◽  
Low Grade ◽  
Imaging Findings ◽  
Mri Findings ◽  
Diffusion Weighted ◽  
Stromal Component

Abstract Background Adenosarcoma is classified as a mixed epithelial and mesenchymal tumor composed of a benign epithelial component and a malignant stromal component. The stromal component in adenosarcoma is usually low grade, and consequently the prognosis is relatively favorable. While, adenosarcoma with sarcomatous overgrowth (SO) is defined as an adenosarcoma in which the sarcomatous component constitutes more than 25% of the tumor. The stromal component is also high-grade sarcoma showing greater nuclear pleomorphism and mitotic activity, thus, it is associated with worse prognosis. MRI findings of adenosarcoma without SO have been described in previous literatures but the imaging findings in adenosarcoma with SO may be poorly defined. Therefore we present two cases of uterine adenosarcoma with SO. Case presentation Patient 1 was a 76-year-old woman referred to our hospital with complaint of abdominal distension and postmenopausal bleeding. Patient 2 was a 57-year-old woman with complaint of lower abdominal pain and abnormal uterine bleeding. On magnetic resonance imaging (MRI), T2 weighted imaging showed a large, heterogeneous high-intensity mass with hyperintense tiny cysts that expanded the uterine cavity and extended into the cervical canal for both patients. On diffusion-weighted imaging (DWI), both masses appeared as high signal intensity. Patient 2 also had a right ovarian adult granulosa cell tumor that may have contributed to development of the adenosarcoma. Patient 1 recurred with peritoneal sarcomatosis 6 months after surgery and died of the disease. Patient 2 also recurred with a left upper lung metastasis 3 months after surgery. Conclusions DWI may depict pathological changes produced by SO of adenosarcoma as high signal intensity, even though SO does not seem to change MRI findings of adenosarcoma on other sequences. Therefore, DWI could potentially predict SO in presumptive adenosarcoma on MRI and the patient’s prognosis. It is also important for pathologists to know if SO can arise in adenosarcoma because they need to examine the tumor thoroughly to determine the percentage of SO component in the tumor volume when SO is present.

scholarly journals The Mechanism Causing High-signal Intensity on Diffusion-weighted Imaging in Adnexal Torsion: Two Case Reports

2017 ◽  
Vol 16 (3) ◽  
pp. 262-264 ◽  
Author(s):  
Shinya Fujii ◽  
Naoko Mukuda ◽  
Kanae Nosaka ◽  
Takeru Fukunaga ◽  
Chie Inoue ◽  
...  
Keyword(s):  
Signal Intensity ◽  
Diffusion Weighted Imaging ◽  
Case Reports ◽  
High Signal Intensity ◽  
High Signal ◽  
Adnexal Torsion ◽  
Diffusion Weighted

A pituitary abscess showing high signal intensity on diffusion-weighted imaging

2006 ◽  
Vol 29 (3) ◽  
pp. 246-248 ◽  
Author(s):  
Takeshi Takayasu ◽  
Fumiyuki Yamasaki ◽  
Atsushi Tominaga ◽  
Toshikazu Hidaka ◽  
Kazunori Arita ◽  
...  
Keyword(s):  
Signal Intensity ◽  
Diffusion Weighted Imaging ◽  
High Signal Intensity ◽  
High Signal ◽  
Pituitary Abscess ◽  
Diffusion Weighted

scholarly journals The potential role of diffusion weighted imaging in the diagnosis of early carotid and vertebral artery dissection

2021 ◽  
Author(s):  
Mohammad Almohammad ◽  
Mete Dadak ◽  
Friedrich Götz ◽  
Frank Donnerstag ◽  
Anita Blanka Tryc ◽  
...  
Keyword(s):  
Vertebral Artery ◽  
Signal Intensity ◽  
Diffusion Weighted Imaging ◽  
Pulse Sequence ◽  
High Signal Intensity ◽  
Artery Dissection ◽  
Mean Deviation ◽  
High Signal ◽  
Diffusion Weighted

Abstract Purpose To investigate the role of the diffusion weighted imaging (DWI) in the acute dissection of internal carotid artery (ICA) and vertebral artery (VA) and assessing the length of intramural hematoma (IMH), caused by dissection. Methods We analyzed 28 patients presenting with a dissection of the ICA and/or VA with respect to the presence of high signal intensity areas on DWI suggestive of dissection and 20 control subjects without arterial dissection, some with and some without atherosclerotic lesions. ICA or VA dissection was defined by clinical and imaging, computed tomography angiography (CTA), MR angiography (MRA), and digital subtraction angiography (DSA) findings. The length of DWI hyperintensity was compared to length of the occlusion or stenosis on the angiographic examination. Results In 28 patients, 30 dissected arteries were analyzed. Time intervals from the onset of the first clinical symptoms to the radiological evaluation ranged from 1.5 h to 42 days. In 28 (93%) of the dissections, a high signal intensity of the affected artery was present on DWI. The measurement of the dissection length on DWI compared to DSA showed a mean deviation of 2.7 mm and a standard deviation of 3.7 mm. Conclusion DWI is a highly sensitive and valuable pulse sequence for the detection of dissected cervical arteries even in the first hours after symptom onset. In contrast to CTA and MRA, DWI can be a potential tool for a reliable measurement of the dissection length.

MRI findings and demographics of elastofibroma dorsi: assessment of diffusion-weighted imaging and contrast enhancement patterns

2017 ◽  
Vol 59 (6) ◽  
pp. 709-715 ◽  
Author(s):  
Maho Tsubakimoto ◽  
Tsuneo Yamashiro ◽  
Nanae Tsuchiya ◽  
Masahiro Okada ◽  
Hiroki Maehara ◽  
...  
Keyword(s):  
Contrast Enhancement ◽  
Signal Intensity ◽  
Diffusion Weighted Imaging ◽  
Enhancement Pattern ◽  
Mri Findings ◽  
Adc Value ◽  
Diffusion Restriction ◽  
Diffusion Weighted ◽  
Elastofibroma Dorsi ◽  
Significant Difference

Background Elastofibroma dorsi is a rare pseudotumoral lesion. Thus, there is no report of magnetic resonance imaging (MRI) findings that investigates multiple patients particularly with respect to diffusion-weighted imaging (DWI) findings and contrast enhancement patterns. Purpose To describe the imaging findings of elastofibroma on MRI, particularly DWI findings and contrast enhancement patterns, and to further investigate patient demographics. Material and Methods Forty-four patients with elastofibroma that underwent MRI were enrolled in this retrospective study. All images were evaluated by two radiologists to visually assess the signal intensity for each sequence. Enhanced elastofibromas were classified into four categories to assess the enhancement pattern. Differences in gender and laterality were also assessed statistically. Results An equal number of men and women were included (n = 22 each). There was no significant difference in laterality ( P = 0.783). All lesions (73 lesions) had low signal intensity on both T1-weighted (T1W) and T2-weighted (T2W) images: heterogeneous in 56, homogeneous in 17. None of the 41 lesions with DWI had true abnormal diffusion restriction. The average ADC value was 1.36 × 10–3 ± 0.29 mm2/s. All 31 lesions that had contrast-enhanced MRI were classified according to enhancement pattern: homogeneous (three lesions, 9.7%); heterogeneous (15 lesions, 48.4%); streak-like (three lesions, 9.7%); and rim-like (ten lesions, 32.2%). Conclusion There were no statistically significant differences in gender or laterality. Elastofibroma showed homogeneous to heterogeneous low signal intensity on T1W and T2W images. No lesion showed abnormal diffusion restriction, and all lesions demonstrated enhancement on MRI.

scholarly journals Pitfalls of diffusion-weighted imaging of the female pelvis

2018 ◽  
Vol 51 (1) ◽  
pp. 37-44 ◽  
Author(s):  
Ana Luisa Duarte ◽  
João Lopes Dias ◽  
Teresa Margarida Cunha
Keyword(s):  
Signal Intensity ◽  
Diffusion Weighted Imaging ◽  
Structural Information ◽  
Biological Tissues ◽  
High Signal ◽  
Female Pelvis ◽  
Diffusion Weighted ◽  
Apparent Diffusion ◽  
Mri Sequences ◽  
Magnetic Resonance Imaging Mri

Abstract Diffusion-weighted imaging (DWI) is widely used in protocols for magnetic resonance imaging (MRI) of the female pelvis. It provides functional and structural information about biological tissues, without the use of ionizing radiation or intravenous administration of contrast medium. High signal intensity on DWI with simultaneous low signal intensity on apparent diffusion coefficient maps is usually associated with malignancy. However, that pattern can also be seen in many benign lesions, a fact that should be recognized by radiologists. Correlating DWI findings with those of conventional (T1- and T2-weighted) MRI sequences and those of contrast-enhanced MRI sequences is mandatory in order to avoid potential pitfalls. The aim of this review article is the description of the most relevant physiological and benign pathological conditions of the female pelvis that can show restricted diffusion on DWI.

scholarly journals Susceptibility Weighted Imaging in Acute Stroke with Co-morbids: Magnetic Resonance Imaging Protocol Revisited

2019 ◽  
pp. 1-8 ◽  
Author(s):  
Fatima Mubarak ◽  
Muhammad Danish Barakzai
Keyword(s):  
Signal Intensity ◽  
Diffusion Weighted Imaging ◽  
Surrogate Marker ◽  
Rank Correlation ◽  
Acute Stage ◽  
High Signal ◽  
Susceptibility Weighted Imaging ◽  
Imaging Protocol ◽  
Diffusion Weighted ◽  
Acute Infarct

Introduction: We aim to investigate ischemic penumbra using Diffusion weighted imaging- Susceptibility weighted imaging mismatch using DWI Alberta Stroke Program Early Computed tomography Stroke Score scoring in patients with multiple co morbid. Methods: From January 2011 to December, 2017; 70 consecutive patients (50 men, 20 women; mean age 64.5; range 45-82 years) with acute infarct on Diffusion weighted imaging (DWI) were selected for the study. Stroke protocol performed including DWI and susceptibility weighted imaging (SWI) on first day and repeat within three days. All initial MR images were interpreted by one Neuroradiologist with more than ten years blind to the clinical findings of each patient. The definition of an acute infarct area was high signal intensity on DWI with dark signal intensity on Apparent diffusion weighted imaging (ADC). The infarct extent was scored using the Alberta Stroke Program Early CT Score (ASPECTS) system. Infarct growth was defined as any new or larger lesion on the second DWI. For correlation with infarct growth, the same topographic system was used to record the extent of the Prominent vessel sign (PVS) on SWI. Spearman’s rank correlation test was used to examine the correlations between PVS score and infarct growth score. Regression was computed, with P<0.05 considered significant. Results: The study included 12 women and 10 men, (mean age 67.1 years). MRI images were initially acquired as stroke protocol (mean 12 hours) in acute stage and the next MRI was done within 3 days after the acute stage. 9 patients had right sided and 13 patients had left sided MCA territory infarct, the mean DWI-ASPECTS score was 4.3 (range 0–9).  PVS was detected in 15 patients (mean score 4.1, range 0–10). Out of 22 patients 9 patients showed no evolution in infarct however in 13 patients evolution was from (ASPECTS mean score 3.95, range 0–9; mean infarct growth score 7.4, range 0–10). 7 patients devoid of PVS in initial MRI, did not exhibited evolution of infarction. Of 15 patients with PVS on initial MRI, 13 (87%) had infarct growth. Correlation between the evolution in infarct size and PVS score was observed (r = 0.86, P<0.001). Conclusion: PVS seen in infarcted territory is related to poor prognosis and this can be reliably used as a surrogate marker of oxygen extraction in penumbra. SWI can predict tissue at risk and can be a replacement for perfusion scan in clinical scenerio of acute ischaemic infarct.

Case 6.6

2014 ◽  
pp. 293-294
Author(s):  
Christine U. Lee ◽  
James F. Glockner
Keyword(s):  
Genetic Disease ◽  
Signal Intensity ◽  
Adrenal Mass ◽  
High Signal Intensity ◽  
High Signal ◽  
Diffusion Weighted Image ◽  
Weighted Image ◽  
Diffusion Weighted ◽  
T2 Weighted Images

35-year-old woman with a genetic disease Axial fat-suppressed FSE T2-weighted images (Figure 6.6.1) demonstrate a large right adrenal mass with scattered regions of high T2-signal intensity. The lesion shows moderately high signal intensity on diffusion-weighted image (b=600 s/mm2) (Figure ...

Conservative treatment for pediatric lumbar spondylolysis to achieve bone healing using a hard brace: what type and how long?

2012 ◽  
Vol 16 (6) ◽  
pp. 610-614 ◽  
Author(s):  
Koichi Sairyo ◽  
Toshinori Sakai ◽  
Natsuo Yasui ◽  
Akira Dezawa
Keyword(s):  
Conservative Treatment ◽  
Bone Healing ◽  
Signal Intensity ◽  
Early Stage ◽  
Ct Scanning ◽  
High Signal Intensity ◽  
High Signal ◽  
Mri Findings ◽  
Lumbar Spondylolysis ◽  
Pars Interarticularis

Object Various kinds of trunk braces have been used to achieve bone healing in cases of pediatric lumbar spondylolysis. However, the optimal brace for achieving bone healing is unclear. The purpose of the present study was to determine in what types of spondylolysis bone healing can be achieved and how long it takes. Methods In this prospective study, 63 pars interarticularis defects (spondylolysis) among 37 patients who were younger than 18 years (mean 13.5 ± 2.7 years) were treated using a hard brace. The youngest patient was 8 years old. Based on the results of CT scanning, the lyses were classified into 3 categories: early, progressive, and terminal defects. Progressive defects were further divided into 2 types according to STIR MRI findings: those with high signal intensity at the adjacent pedicle and those with low signal intensity (that is, a normal appearance). A hard brace, such as a molded plastic thoracolumbosacral orthosis, was used to immobilize the trunk. Approximately every 3 months, CT scanning was performed to evaluate bone healing until approximately 6 months. Results The union rates were 94%, 64%, 27%, and 0% for the early, progressive with high signal intensity, progressive with low signal intensity, and terminal defects, respectively. It was noted that no terminal defect was healed using conservative treatment. The mean time to healing among the defects that showed bone healing was 3.2, 5.4, and 5.7 months for the early, progressive with high signal intensity, and progressive with low signal intensity groups, respectively. Conclusions Patients with early-stage defects are the best candidates for conservative treatment with a hard brace because more than 90% of such cases can be healed in 3 months.

Sign in / Sign up

Export Citation Format

Share Document