scholarly journals Protective effects and mechanisms of Terminalia catappa L. methenolic extract on hydrogen-peroxide-induced oxidative stress in human skin fibroblasts

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Ya-Han Huang ◽  
Po-Yuan Wu ◽  
Kuo-Ching Wen ◽  
Chien-Yih Lin ◽  
Hsiu-Mei Chiang
Keyword(s):  
Oxidative Stress ◽  
Hydrogen Peroxide ◽  
Human Skin ◽  
Skin Fibroblasts ◽  
Protective Effects ◽  
Human Skin Fibroblasts ◽  
Terminalia Catappa

scholarly journals Protective Effects of Aucubin Isolated from Eucommia ulmoides against UVB-Induced Oxidative Stress in Human Skin Fibroblasts

2005 ◽  
Vol 28 (7) ◽  
pp. 1244-1248 ◽  
Author(s):  
Jin Nyoung Ho ◽  
Yoo Hyun Lee ◽  
Jong Seok Park ◽  
Woo Jin Jun ◽  
Hye Kyung Kim ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Human Skin ◽  
Skin Fibroblasts ◽  
Eucommia Ulmoides ◽  
Protective Effects ◽  
Human Skin Fibroblasts

Protective and Anti-Aging Effects of 5 Cosmeceutical Peptide Mixtures on Hydrogen Peroxide-Induced Premature Senescence in Human Skin Fibroblasts

2021 ◽  
pp. 1-9
Author(s):  
Yun Wu ◽  
Kun Cao ◽  
Wei Zhang ◽  
Guangxian Zhang ◽  
Maojun Zhou
Keyword(s):  
Hydrogen Peroxide ◽  
Human Skin ◽  
Optimal Concentration ◽  
Skin Fibroblasts ◽  
Skin Barrier Function ◽  
Premature Senescence ◽  
Protective Effects ◽  
Human Skin Fibroblasts ◽  
Aging Effects ◽  
Peptide Mixtures

Skin aging usually leads to the excessive deterioration of the dermal extracellular matrix, loss of antimicrobial function, loss of skin barrier function, and a series of inflammatory processes. Bioactive peptides have been widely used in cosmetics due to their protective effects on skin and efficient absorption. Combination of different peptides may lead to synergistic or antagonistic effects, so different formulas need to be designed and tested properly. In this study, 5 functional cosmeceutical peptides were tested on their individual and mixed activities to detect a suitable anti-aging and protective formula from our experiments. After the individual activity test, the optimal concentration is 200 μg/mL of carnosine for the superoxide dismutase (SOD) activity, 200 μg/mL of GHK peptide for the hydroxyproline (HYP) content activity, 100 μg/mL of acetyl tetrapeptide-5 for the angiotensin-converting enzyme 1 activity, 400 μg/mL of hexapeptide-11 for the HYP content activity, and 400 μg/mL of acetyl hexapeptide-3 for the catecholamine content activity. According to the optimal concentration of these 5 cosmeceutical peptides, 6 formulations of peptide mixtures were designed and tested for their anti-aging activities and protective effects against hydrogen peroxide-induced premature senescence in human skin fibroblasts. One of the cosmeceutical peptide mixtures (carnosine + acetyl tetrapeptide-5 + hexapeptide-11 + acetyl hexapeptide-3) significantly reduced the intracellular malondialdehyde and hydroxyl free radical contents and increased the HYP and human elastin contents as well as the enzymatic activities of SOD and glutathione peroxidase. Our study suggests that this formula of cosmeceutical peptide mixtures could be a promising agent for use in anti-aging and protective cosmetics.

scholarly journals Protective Effects of Fucoidan against UVB-Induced Oxidative Stress in Human Skin Fibroblasts

2010 ◽  
Vol 20 (1) ◽  
pp. 27-32 ◽  
Author(s):  
Mi-Jung Ku ◽  
Myeong-Sook Lee ◽  
Hee-Jung Moon ◽  
Yong-Hwan Lee
Keyword(s):  
Oxidative Stress ◽  
Human Skin ◽  
Skin Fibroblasts ◽  
Protective Effects ◽  
Human Skin Fibroblasts

Protective Effects of Green Tea Seed Extract against UVB-irradiated Human Skin Fibroblasts

2014 ◽  
Vol 43 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Ok Kyung Kim ◽  
Da-Eun Nam ◽  
Min-Jae Lee ◽  
Namgil Kang ◽  
Jae-Youn Lim ◽  
...  
Keyword(s):  
Human Skin ◽  
Green Tea ◽  
Seed Extract ◽  
Skin Fibroblasts ◽  
Protective Effects ◽  
Human Skin Fibroblasts
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