Vitamin E δ-tocotrienol sensitizes human pancreatic cancer cells to TRAIL-induced apoptosis through proteasome-mediated down-regulation of c-FLIPs

Rony A. Francois; Anying Zhang; Kazim Husain; Chen Wang; Sean Hutchinson; Michael Kongnyuy; Surinder K. Batra; Domenico Coppola; Said M. Sebti; Mokenge P. Malafa

doi:10.1186/s12935-019-0876-0

Vitamin E δ-tocotrienol sensitizes human pancreatic cancer cells to TRAIL-induced apoptosis through proteasome-mediated down-regulation of c-FLIPs

Cancer Cell International ◽

10.1186/s12935-019-0876-0 ◽

2019 ◽

Vol 19 (1) ◽

Author(s):

Rony A. Francois ◽

Anying Zhang ◽

Kazim Husain ◽

Chen Wang ◽

Sean Hutchinson ◽

...

Keyword(s):

Pancreatic Cancer ◽

Vitamin E ◽

Cancer Cells ◽

Human Pancreatic Cancer ◽

Down Regulation ◽

Pancreatic Cancer Cells ◽

Induced Apoptosis

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Lipoxygenase Inhibition Induced Apoptosis, Morphological Changes, and Carbonic Anhydrase Expression in Human Pancreatic Cancer Cells

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.1999.1824 ◽

1999 ◽

Vol 266 (2) ◽

pp. 392-399 ◽

Cited By ~ 77

Author(s):

Xian-Zhong Ding ◽

Charles A. Kuszynski ◽

Tarek H. El-Metwally ◽

Thomas E. Adrian

Keyword(s):

Pancreatic Cancer ◽

Carbonic Anhydrase ◽

Cancer Cells ◽

Morphological Changes ◽

Human Pancreatic Cancer ◽

Pancreatic Cancer Cells ◽

Lipoxygenase Inhibition ◽

Induced Apoptosis

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2-Triazenoazaindoles: A novel class of triazenes inducing transcriptional down-regulation of EGFR and HER-2 in human pancreatic cancer cells

International Journal of Oncology ◽

10.3892/ijo.2011.1272 ◽

2011 ◽

Vol 40 (4) ◽

pp. 914-922 ◽

Cited By ~ 3

Author(s):

JAN N. KREUTZER ◽

ALESSIA SALVADOR ◽

PATRIZIA DIANA ◽

GIROLAMO CIRRINCIONE ◽

DANIELA VEDALDI ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Human Pancreatic Cancer ◽

Down Regulation ◽

Pancreatic Cancer Cells ◽

Her 2

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Abstract 4738: The early response protein EGR-1 mediates vitamin E γ-tocotrienol-induced apoptosis in pancreatic cancer cells

10.1158/1538-7445.am2012-4738 ◽

2012 ◽

Author(s):

Chen Wang ◽

Jose M. Pimiento ◽

Kazim Husain ◽

Anying Zhang ◽

Zhongsheng Tong ◽

...

Keyword(s):

Pancreatic Cancer ◽

Vitamin E ◽

Cancer Cells ◽

Early Response ◽

Pancreatic Cancer Cells ◽

Induced Apoptosis

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Salicylates Inhibit NF-κB Activation and Enhance TNF-α-Induced Apoptosis in Human Pancreatic Cancer Cells

Journal of Surgical Research ◽

10.1006/jsre.1998.5560 ◽

1999 ◽

Vol 83 (1) ◽

pp. 56-61 ◽

Cited By ~ 55

Author(s):

Theodore P. McDade ◽

Richard A. Perugini ◽

Frank J. Vittimberga ◽

Rebecca C. Carrigan ◽

Mark P. Callery

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Human Pancreatic Cancer ◽

Pancreatic Cancer Cells ◽

Tnf Α ◽

Induced Apoptosis

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GDC-0980-induced apoptosis is enhanced by autophagy inhibition in human pancreatic cancer cells

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2014.09.115 ◽

2014 ◽

Vol 453 (3) ◽

pp. 533-538 ◽

Cited By ~ 14

Author(s):

Jian-ying Tang ◽

Tu Dai ◽

Hui Zhang ◽

Wu-jun Xiong ◽

Ming-zheng Xu ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Human Pancreatic Cancer ◽

Pancreatic Cancer Cells ◽

Induced Apoptosis ◽

Autophagy Inhibition

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Flavonoid apigenin modified gene expression associated with inflammation and cancer and induced apoptosis in human pancreatic cancer cells through inhibition of GSK-3β/NF-κB signaling cascade

Molecular Nutrition & Food Research ◽

10.1002/mnfr.201300307 ◽

2013 ◽

Vol 57 (12) ◽

pp. 2112-2127 ◽

Cited By ~ 37

Author(s):

Jodee L. Johnson ◽

Elvira Gonzalez de Mejia

Keyword(s):

Gene Expression ◽

Pancreatic Cancer ◽

Cancer Cells ◽

Human Pancreatic Cancer ◽

Signaling Cascade ◽

Pancreatic Cancer Cells ◽

Gsk 3Β ◽

Induced Apoptosis

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Somatostatin receptor subtype 2 sensitizes human pancreatic cancer cells to death ligand-induced apoptosis

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.0136771100 ◽

2002 ◽

Vol 100 (1) ◽

pp. 155-160 ◽

Cited By ~ 78

Author(s):

J. Guillermet ◽

N. Saint-Laurent ◽

P. Rochaix ◽

O. Cuvillier ◽

T. Levade ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Somatostatin Receptor ◽

Human Pancreatic Cancer ◽

Receptor Subtype ◽

Pancreatic Cancer Cells ◽

Induced Apoptosis ◽

Somatostatin Receptor Subtype 2

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Correction: Down-Regulation of 5-HT1B and 5-HT1D Receptors Inhibits Proliferation, Clonogenicity and Invasion of Human Pancreatic Cancer Cells

PLoS ONE ◽

10.1371/journal.pone.0110067 ◽

2014 ◽

Vol 9 (9) ◽

pp. e110067 ◽

Cited By ~ 3

Author(s):

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Human Pancreatic Cancer ◽

Down Regulation ◽

Pancreatic Cancer Cells

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Role of the eIF4E binding protein 4E-BP1 in regulation of the sensitivity of human pancreatic cancer cells to TRAIL and celastrol-induced apoptosis

Biology of the Cell ◽

10.1111/boc.201300021 ◽

2013 ◽

Vol 105 (9) ◽

pp. 414-429 ◽

Cited By ~ 9

Author(s):

Reka Chakravarthy ◽

Michael J. Clemens ◽

Grisha Pirianov ◽

Nectarios Perdios ◽

Satvinder Mudan ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Binding Protein ◽

Human Pancreatic Cancer ◽

Pancreatic Cancer Cells ◽

Induced Apoptosis

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Expression of ROCK-1 in Human Pancreatic Cancer: Its Down-Regulation by Morpholino Oligo Antisense Can Reduce the Migration of Pancreatic Cancer Cells In Vitro

Pancreas ◽

10.1097/00006676-200204000-00007 ◽

2002 ◽

Vol 24 (3) ◽

pp. 251-257 ◽

Cited By ~ 25

Author(s):

Kenzo Kaneko ◽

Kennichi Satoh ◽

Atsushi Masamune ◽

Akihiko Satoh ◽

Tooru Shimosegawa

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Human Pancreatic Cancer ◽

Down Regulation ◽

Pancreatic Cancer Cells

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