scholarly journals Imaging predictor of ophthalmic involvement in maxillary sinus cancer during super selective intra-arterial cisplatin infusion and concomitant radiotherapy (RADPLAT)

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Hirokazu Ashida ◽  
Takao Igarashi ◽  
Yosuke Nozawa ◽  
Yohei Munetomo ◽  
Takahiro Higuchi ◽  
...  

Abstract Objective To investigate the predictability of ophthalmic artery involvement in maxillary sinus cancer using preprocedural contrast enhanced CT and MRI. Methods We analyzed advanced (T3, T4a, and T4b) primary maxillary sinus squamous cell carcinoma treated with super-selective intra-arterial cisplatin infusion and concomitant radiotherapy (RADPLAT) from Oct 2016 to Mar 2020. Two diagnostic radiologists evaluated the tumor invasion site around the maxillary sinus using preprocedural imaging. These results were compared with the angiographic involvement of the ophthalmic artery using statistical analyses. We also evaluated our RADPLAT quality using complication rate, response to treatment, local progressive free survival (LPFS), and overall survival (OS). Results Twenty patients were included in this study. There were ten cases of ophthalmic artery tumor stain and there was a correlation between ophthalmic artery involvement and invasion for ethmoid sinus with statistically significant differences. Other imaging findings were not associated with ophthalmic artery involvement. Conclusions Ethmoid sinus invasion on preprocedural imaging could suggest ophthalmic artery involvement in maxillary sinus cancer. It may be useful in predicting prognosis and treatment selection.

2021 ◽  
Vol 156 (0) ◽  
pp. 90-94
Author(s):  
Shigeru Matsuda ◽  
Yuki Yamaguchi ◽  
Daiki Mochizuki ◽  
Atsushi Imai ◽  
Masataka Sone ◽  
...  

2013 ◽  
Vol 109 (12) ◽  
pp. 2980-2986 ◽  
Author(s):  
A Homma ◽  
T Sakashita ◽  
D Yoshida ◽  
R Onimaru ◽  
K Tsuchiya ◽  
...  

2015 ◽  
Vol 118 (12) ◽  
pp. 1436-1442 ◽  
Author(s):  
Kousuke Yoshifuku ◽  
Kengo Nishimoto ◽  
Tsutomu Matsuzaki ◽  
Shigeto Matsushita

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Yasuo Kosugi ◽  
Terufumi Kawamoto ◽  
Masaki Oshima ◽  
Mitsuhisa Fujimaki ◽  
Shinichi Ohba ◽  
...  

Abstract Background The aim of this study was to evaluate the long-term treatment results of combined superselective intraarterial chemotherapy and radiation therapy for advanced maxillary sinus cancer (MSC) and the incidence of regional lymph node failure, and to reveal the clinical and anatomical predictive factors for metastasis. Methods We retrospectively evaluated 55 consecutive patients with locally advanced squamous cell carcinoma of the maxillary sinus who were treated with external radiotherapy and superselective intraarterial chemotherapy. Elective nodal irradiation (ENI) was performed only in the clinical node-positive (cN+) cases and not in the clinical node-negative (cN0) cases. Results: Thirty-eight patients were cN0, and 17 were cN+ at diagnosis. Regional lymph node metastases occurred in 7 of 38 patients with cN0, and 2 of 17 with cN+ during the median follow-up period of 36 months. There were more cases of high-grade (3 or 4) late adverse events in the ENI group than in the non-ENI group (13% vs. 41%, respectively; p = 0.03). In cN0 cases without ENI, invasion of the pterygoid plates (57% vs. 90%; p < 0.01) and oral cavity (35% vs. 92%, with invasion vs without invasion, respectively; p = 0.02) was significantly correlated with a low 5-year regional recurrence-free rate. Conclusions Patients with MCS and invasion of the pterygoid plates and oral cavity can be considered appropriate candidates for ENI.


2008 ◽  
Vol 32 (3) ◽  
pp. 397-402 ◽  
Author(s):  
Etsushi Iida ◽  
Munemasa Okada ◽  
Toshifumi Mita ◽  
Matakazu Furukawa ◽  
Katsuyoshi Ito ◽  
...  

Rare Tumors ◽  
2009 ◽  
Vol 1 (2) ◽  
pp. 110-114 ◽  
Author(s):  
Hye Sung Won ◽  
Sang Hoon Chun ◽  
Bum-soo Kim ◽  
So Ryoung Chung ◽  
Ie Ryung Yoo ◽  
...  

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