scholarly journals Transcatheter and intraoperative device closure of atrial septal defect in infants under three years of age

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Yangyang Han ◽  
Xiquan Zhang ◽  
Fengwei Zhang
Keyword(s):  
Atrial Septal Defect ◽  
Hospital Stay ◽  
Clinical Data ◽  
Septal Defect ◽  
Postoperative Hospital Stay ◽  
Device Closure ◽  
Young Infants ◽  
Group A ◽  
Group B

Abstract Background Transcatheter and intraoperative device closures have been widely used in the treatment of secundum atrial septal defect (ASD). However, for young infants with ASD, device closure remains controversial, and such treatment features limited data. We compared the clinical data and follow-up results of percutaneous and intraoperative device closure for ASD to evaluate the feasibility, safety, and efficacy of both treatments in infants under 3 years of age. Methods From September 2010 to September 2018, 186 children under 3 years of age with significant secundum ASD were included in this study. A total of 88 and 98 patients were divided into groups A (transcatheter device closure) and B (intraoperative device closure), respectively. The clinical data and follow-up results of the two groups were analyzed retrospectively. Result The mean age and weight of patients in group A were significantly higher than those in group B. The proportion of complex ASDs (multiples or rims deficiency) and the device/weight ratio in group B were significantly higher than those in group A. Successful closure was obtained in 86 (97.7%) and 96 (98.0%) infants in groups A and B, respectively, with two failed cases in each group (2.3% vs 2%). The rate of periprocedural complications reached 13.6 and 26.5% for groups A and B (P = 0.058), respectively. The durations of the procedure and postoperative hospital stay in group A were significantly shorter than those in group B (P < 0.05). Excellent follow-up results were observed in both groups. At present, no death nor major complications have occurred. Symptoms either resolved completely or improved significantly for all symptomatic infants. No residual shunts at the 6th month of follow-up evaluation were observed. Patients with failure to thrive gained weight appropriately for age, and the structure and hemodynamic parameters significantly improved during follow-up. Conclusion Transcatheter and intraoperative device closure are feasible, effective, and safe methods for the treatment of ASDs in infants under 3 years of age. Considering improved cosmetic effect and the short duration of the procedure and postoperative hospital stay, transcatheter is preferred for patients with appropriate conditions. Intraoperative device closure can be performed as an alternative to percutaneous closure, particularly for infants with large, complex ASDs, young age, or low-body weight.

scholarly journals The Effect of Preoperative Pulmonary Arterial Hypertension on Incidence of Postoperative Atrial Fibrillation after Surgical Closure of Atrial Septal Defect (Secundum)

2018 ◽  
Vol 13 (1) ◽  
pp. 17-20
Author(s):  
AKM ManzurulAlam ◽  
Istiaq Ahmed ◽  
Manzil Ahmed ◽  
Mohammad Ashraf ◽  
Mamun Hossaim ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Atrial Septal Defect ◽  
Septal Defect ◽  
Group A ◽  
Pulmonary Arterial ◽  
Group B ◽  
Substantial Morbidity

Background: Atrial tachyarrhythmias are common among adults with ASD and contribute to substantial morbidity. Atrial flutter and atrial fibrillation are well-described complications of atrial septal defect (ASD) and are associated with substantial morbidity. The cause of AF in ASD is multifactorial in nature. It has been proposed that it is related to atrial dilatation, the increase in pulmonary pressure, and ventricular dysfunction. Early surgical intervention may reduce the long-term risk of developing atrial arrhythmias. Studies demonstrated that cardiac remodeling occurred after closure of an ASD, even in older patients. This study aimed to find out the pulmonary hypertension (PAH) as a predictor of postoperative atrial fibrillation in patients after surgery for secundum type atrial septal defect closure.Methods: This Prospective Observational Study carried out in department of cardiac surgery, National Institute of Cardiovascular Disease (NICVD) and Hospital, Dhaka, Bangladesh during the period of July, 2015 to June, 2016. Total 54 patients are taken and then grouped into group A and group B. Each group contains 27 patients. Group A include Patients with ASD secundum without PAH. Group B Patients with ASD secundum with PAH. All patients were evaluated with M-mode, 2D and color Doppler transthoracic echocardiography and ECG before operation, at discharge, after one month and at 3 months follow-up. Statistical analysis of the results was obtained by windows based computer software with statistical package for the social sciences program (SPSS version 21).Results: To compare atrial fibrillation postoperative at discharge and postoperative after 1 and 3 months follow-up it was found In group B 8 (29.62%) patients had AF postoperatively, during discharge 8 (29.62%) patients had AF, after 1 month 7 (25.93%) patient had AF, after 3 months 6 (22.22%) patients had AF. No AF was found in Group A patients during postoperatively, during discharge, after 1 month & 3 months follow up. Statistical significant difference was found in between two groups (p<0.05).Conclusion: The surgical correction of atrial septal defect (ASD) is safe and effective procedure. Our studyshowed that the haemodynamic and electrophysiological results of the surgical repair of ASD secundum was superior before the development of pulmonary arterial hypertension. After surgical correction of ASD secundum raised pulmonary artery pressure became lower gradually. Atrial fibrillation developed in patient group with pulmonary arterial hypertension in postoperative period remain persistent in most patients in the follow up period, few converted to sinus rhythmUniversity Heart Journal Vol. 13, No. 1, January 2017; 17-20

scholarly journals Antrinių prieširdžių pertvaros defektų gydymo chirurginiu ir perkateteriniu būdu ankstyvųjų rezultatų ir komplikacijų palyginimas

2010 ◽  
Vol 8 (3) ◽  
pp. 0-0
Author(s):  
Lina Gumbienė ◽  
Vytautas Juknevičius ◽  
Valdas Bilkis ◽  
Virgilijus Tarutis ◽  
Diana Zakaraitė ◽  
...  
Keyword(s):  
Atrial Septal Defect ◽  
Hospital Stay ◽  
Septal Defect ◽  
Secundum Atrial Septal Defect ◽  
Atrial Septal Defect Closure ◽  
Surgical Closure ◽  
Early Results ◽  
Group A ◽  
The Mean ◽  
Group B

Lina Gumbienė1, Vytautas Juknevičius2 , Valdas Bilkis1 , Virgilijus Tarutis1 , Diana Zakaraitė1 , Rimantas Karalius1 , Giedrė Nogienė1 , Alicija Dranenkienė1 1 Vilniaus universiteto Širdies ir kraujagyslių ligų klinika, Santariškių g. 2, LT-08661 VilniusEl. paštas: [email protected] Vilniaus universitetas Medicinos fakultetas Tikslas: Palyginti prieširdžių pertvaros defekto chirurginio ir perkateterinio gydymo metodų ankstyvuosius rezultatus ir komplikacijas. Ligoniai ir metodai: Retrospektyviai tirti vyresni nei 13 metų amžiaus ligoniai, kuriems 2006–2009 m. mūsų ligoninėje buvo gydytas antrinis prieširdžių pertvaros defektas. Rezultatai: 62 ligoniams atlikta chirurginė defekto korekcija (A grupė), 35 ligoniams defektas buvo panaikintas perkateteriniu būdu (B grupė). Vidutinis A grupės ligonių amžius buvo 36,1 metų (nuo 13 iki 71), B grupės – 40,51 metų (nuo 14 ik 72). Viena A grupės ligonė mirė po operacijos išsivysčius infekcinei komplikacijai ir dauginiam organų nepakankamumui. Vienai B grupės ligonei defekto panaikinti nepavyko, dar vienai pacientei po procedūros liko nedidelis nuosrūvis tarp prieširdžių. Komplikacijų nepatyrė daugiau B grupės ligonių negu A grupės (atitinkamai 91,4 % ir 59,67 %, p < 0,05). Sunkių komplikacijų išsivystė tik chirurginiu būdu gydytiems ligoniams. B grupės ligonių hospitalizacijos trukmė buvo statistiškai reikšmingai mažesnė negu A grupės (atitinkamai 4,4 ± 2,6 ir 16,7 ± 16,6 paros, p < 0,0001). Išvados: Ligoniams, kuriems prieširdžių pertvaros defektas uždaromas perkateteriniu būdu, išsivysto mažiau ankstyvųjų pooperacinių komplikacijų ir jų hospitalizacijos laikas trumpesnis. Po chirurginės prieširdžių pertvaros defekto korekcijos atsiradusios ankstyvosios pooperacinės komplikacijos sietinos su buvusiu triburio vožtuvo nesandarumu. Reikšminiai žodžiai: įgimtos širdies ydos, prieširdžių pertvaros defektas, chirurgija, perkateterinis uždarymas Comparison of early results and complications in transcatheter and surgical closure of secundum atrial septal defect Lina Gumbienė1, Vytautas Juknevičius2 , Valdas Bilkis1 , Virgilijus Tarutis1 , Diana Zakaraitė1 , Rimantas Karalius1 , Giedrė Nogienė1 , Alicija Dranenkienė1 1Vilnius University, Clinic of Cardiovascular Diseases, Santariškių str. 2, LT-08661 Vilnius, LithuaniaE-mail: [email protected] University Faculty of Medicine Objective: To compare early results and complications in transcatheter and surgical closure of the secundum atrial septal defect (ASD). Patients and methods: rectal prolapse, rectal cancer, faecal incontinence, Altemeyer operation Results: Sixty-two patients underwent surgical correction (Group A), 35 patients underwent transcatheter ASD closure with Amplatzer septal occluder (Group B). The mean age in Group A was 36.14 (13–71) years, in Group B 40,51 (14–72) years. One patient in Group A died because of postoperative infection, heart and renal failure. In Group B, the procedure was unsuccessful in one patent, and residual shunt was found in one patient. The percentage of patients without complications was higher in Group B (91.4% versus 59.7% in Group A, p < 0.05). Severe complications were diagnosed only in the surgical (A) group. The mean length of hospital stay was shorter in Group B (4.4 ± 2.64 days) compared with Group A (16.69 ± 16.55 days, p < 0.0001). Conclusions: The lower rate of early complications and a shorter hospital stay were observed in the transcatheter atrial septal defect closure group. More frequent complications after surgery could have been caused by the insufficiency of the tricuspid valve. Key words: congenital heart disease, atrial septal defect, surgery, transcatheter closure

scholarly journals ACUTE CHOLECYSTITIS

2010 ◽  
Vol 17 (02) ◽  
pp. 185-192
Author(s):  
TARIQ HASSAN CH ◽  
ASGHAR ALI ◽  
MUNAWAR JAMIL
Keyword(s):  
Hospital Stay ◽  
Wound Dehiscence ◽  
Biliary Tree ◽  
Postoperative Hospital Stay ◽  
Total Hospital ◽  
Acute Calculous Cholecystitis ◽  
Total Hospital Stay ◽  
Group A ◽  
The Mean ◽  
Group B

Introduction: Gallstones are common biliary pathology. The Vast majority of subjects are asymptomatic. About 0.2% of the population suffering from gallstones develop acute cholecystitis every year. In case of acute calculous cholecystitis, cholecystectomy can be performed early i.e during the same admission or interval i.e after 6 weeks of conservative management. Objective: To compare the early and interval cholecystectomy in acute calculous cholecystitis for morbidity, postoperative hospital stay, total hospital stay and complications. Study Design: Quasi-experimental study. Setting: Department of Surgery Bahawal Victoria Hospital Bahawalpur. Duration of Study: Two year study from December 2007 to December 2009. Subject and Methods: Sixty patients fulfilling the inclusion criteria were selected for this study. The patients were divided into two groups. Group A patients were managed by early cholecystectomy and group B patients by intervalcholecystectomy. Postoperatively patients were evaluated for postoperative hospital stay, total hospital stay and postoperative complications. Results: The mean age of the patients in group A was 42.2 + 10.7 years and in group B was 42.2+ 10.7 years. The Male to female ratio was 1:4 in both groups. The mean postoperative hospital stay in group A was 4.0+ 1.8days and in group B was 3.8+ 1.4 days. The mean total hospital stayin group A was 6.5 + 1.7 days and in group B was 10.2 + 1.3 days. The P value was less than 0.001, which was significant. In distribution of postoperative complications, in group A there were 1(3.3%) injury to biliary tree, 4(13.3%) wound infection,1(3.3%) wound haematoma, 3 (10%) seroma and 1(3.3%) wound dehiscence. While in group B there were 1(3.3%) injury to biliary tree, 3(10%) wound infection,2 (6.7%) wound haematoma, 2(6.7%) & no patient of wound dehiscence. Conclusion: Our study suggests that early cholecystectomy is a better treatment option than interval cholecystectomy because it has less total hospital stay, needs single hospital visit and has no risk of developing complications during wait for surgery.

scholarly journals Comparison of conventional fenestration discectomy with Transforaminal endoscopic lumbar discectomy for treating lumbar disc herniation:minimum 2-year long-term follow-up in 1100 patients

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Quanyi Li ◽  
Yongchun Zhou
Keyword(s):  
Hospital Stay ◽  
Lumbar Disc ◽  
Length Of Hospital Stay ◽  
Bed Rest ◽  
Intraoperative Blood Loss ◽  
Postoperative Length ◽  
Group A ◽  
Group B ◽  
Endoscopic Lumbar Discectomy

Abstract Purpose To compare the efficacy of conventional interlaminar fenestration discectomy (IFD) with transforaminal endoscopic lumbar discectomy (TELD) for treating lumbar disc herniation (LDH). Methods The clinical data of 1100 patients who had been diagnosed with LDH between January 2012 and December 2017 were retrospectively analysed. IFD was performed on 605 patients in Group A, whereas TELD was performed on 505 patients in Group B. The Oswestry Disability Index, Visual Analogue Scale for pain and modified MacNab criteria were used to evaluate the outcomes. The surgery duration, intraoperative blood loss, postoperative off-bed activity and postoperative length of hospital stay were recorded. Results The follow-up period ranged from 24 to 60 months, with an average of 43 months. The excellent and good outcome rates were 93.5% in Group A and 92.6% in Group B. There was no significant difference in efficacy between the groups (P > 0.05). However, Group B had significantly less intraoperative blood loss and shorter bed rest duration and postoperative length of hospital stay than Group A (P < 0.05). There were two cases of postoperative recurrence in Group A and three in Group B. Conclusions Although conventional IFD and TELD had similar levels of efficacy in treating LDH, TELD had several advantages. There was less intraoperative bleeding, shorter length of hospital stay and shorter bed rest duration. It can be considered a safe and effective surgical option for treating LDH.

Repair of isolated atrial septal defect in infants less than 12 months improves symptoms of chronic lung disease or shunt-related pulmonary hypertension

2020 ◽  
Vol 30 (4) ◽  
pp. 511-520 ◽  
Author(s):  
Dafni Charisopoulou ◽  
Roberta Margarita Bini ◽  
Gillian Riley ◽  
Kalai Janagarajan ◽  
Shahin Moledina ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Atrial Septal Defect ◽  
Lung Disease ◽  
Chronic Lung Disease ◽  
Septal Defect ◽  
Z Score ◽  
Disease Group ◽  
Early Signs ◽  
Group A ◽  
Group B

AbstractIntroduction:Infants with isolated atrial septal defects are usually minimally symptomatic, and repair is typically performed after infancy. Early repair may be considered if there is high pulmonary blood flow and reduced respiratory reserve or early signs of pulmonary hypertension. Our aim was to review the characteristics and outcomes of a cohort of patients who underwent infant repair at our institute.Methods:The study included 56 infants (28 female, 19 trisomy 21) with isolated atrial septal defect (age: 8 months (1.5–12), weight: 6 kg (2.8–7.5), echo Qp/Qs: 1.9 ± 0.1) who underwent surgical closure (20 fenestrated). Three groups were identified: 1) chronic lung disease and pulmonary hypertension (group A: n = 28%); 2) acutely unwell infants with pulmonary hypertension but no chronic lung disease (group B: n = 20, 36%); and 3) infants with refractory congestive heart failure without either pulmonary hypertension or chronic lung disease (group C: n = 9, 16%).Results:Post-operatively, pulmonary hypertension infants (47/56) showed improvement in tricuspid annular plane systolic excursion z-score (p < 0.001) and right ventricular systolic/diastolic duration ratio (p < 0.05). All ventilator (14.3%) or oxygen-dependent (31.6%) infants could be weaned within 2 weeks after repair. One year later, weight z-score increased in all patients and by +1 in group A, +1.3 in group B and +2 in group C. Over a median follow-up of 1.4 years, three patients died, four patients continued to have pulmonary hypertension evidence and two remained on targeted pulmonary hypertension therapy.Conclusion:Atrial septal defect repair within the first year may improve the clinical status and growth in infants with early signs of pulmonary hypertension or those requiring respiratory support and facilitate respiratory management.

scholarly journals Is the Sac Waiting to Rupture? Sinus of Valsalva Aneurysm

Aorta ◽  
2016 ◽  
Vol 04 (03) ◽  
pp. 105-107 ◽  
Author(s):  
Ankur Phatarpekar ◽  
Milind Phadke ◽  
Charan Lanjewar ◽  
Prafulla Kerkar
Keyword(s):  
Atrial Septal Defect ◽  
Septal Defect ◽  
Sinus Of Valsalva ◽  
Device Closure ◽  
Sinus Of Valsalva Aneurysm ◽  
Lost To Follow Up

AbstractCompletely asymptomatic sinus of Valsalva aneurysms are rare entities, and there is no consensus regarding their management. We present the case of a patient who underwent atrial septal defect device closure at 5 years of age and was lost to follow-up, then presented 6 years later with unruptured sinus of Valsalva aneurysm and was closely followed. The aneurysm eventually ruptured and was successfully operated on with good outcomes.

scholarly journals The Combination of Oral PDE5-Inhibitor (Sildenafil) And Oral Prostacy- clin Analogue (Beraphrost) Therapy for Increasing Quality of Life in Adults with Pulmonary Arterial Hypertension Related to Uncorrected Secundum Atrial Septal Defect

2021 ◽  
Vol 2 (4) ◽  
pp. 20-24
Author(s):  
Heny Martini ◽  
Muhammad Rizki Fadlan ◽  
Akhmad Isna Nurudinulloh
Keyword(s):  
Quality Of Life ◽  
Atrial Septal Defect ◽  
Septal Defect ◽  
Secundum Atrial Septal Defect ◽  
Phone Calls ◽  
Group A ◽  
Pulmonary Arterial ◽  
Group B ◽  
Dependent Mechanism

Background : Sildenafil, an oral phosphodiesterase type-5 inhibitor, has vasodilatory effects through a cyclic guanosine 3,5-monophosphate–dependent mechanism, whereas beraprost, an oral prostacyclin analog, induces vasorelaxation through a cAMP-dependent mechanism. This combination has often used but there was little detailed study on it Objectives : To investigate whether the combination of oral sildenafil and beraprost is superior to sildenafil alone in in adult patients with Pulmonary Arterial Hypertention (PAH) related uncorrected secundum Atrial Septal Defect (ASD). Methods : Patients with secundum ASD who developed PAH divided into two group. Group A received oral sildenafil 3x40 mg and oral beraphrost 3x20 mcg. Group B received oral sildenafil only 3x40 mg in a 12-week. Health-related quality of life (HRQoL) was recorded by patients using the Medical Outcomes Study 36-item short form (SF-36) questionnaires at baseline and after 12 of therapy. Therapy adherence was achieved through a series of phone calls and a four-weekly hospital visit. Every normal follow-up appointment included an examina- tion of side effects and a dosage modification based on the clinical situation Results: We didn’t found any significant of proportion different in cofounding factor between groups. Compared with Group B, Group A had better functional capacity, limitation to physical health, energy fatigue, pain, and health change (P=0.00, P=0.03, P=0.044, P=0.026, P=0.008, respectively). Conclusion: Combination between oral sildenafil therapy 40 mg three times per day and beraphrost 20 mcg two times per day significantly increase the HRQoL in PAH patients in uncorrected secundum ASD compared sildena- fil alone

scholarly journals Outcome of Exernal and Internal Drainage of Urine after Anderson Hynes Pyeloplasty - A Comparative Study

2013 ◽  
Vol 2 (1) ◽  
pp. 22-25
Author(s):  
AM Shahinoor ◽  
MMR Shibli ◽  
MAB Akan ◽  
M Anisuzzaman ◽  
MN Islam ◽  
...  
Keyword(s):  
Renal Function ◽  
Hospital Stay ◽  
Postoperative Hospital Stay ◽  
Paediatric Surgery ◽  
Nephrostomy Tube ◽  
Split Renal Function ◽  
Unilateral Hydronephrosis ◽  
Group A ◽  
Group B ◽  
Medical University

Background: Hydronephrosis in children is a common abnormality of the kidney. Surgical intervention in patient with hydronephrosis is to improve urinary drainage and to preserve renal function. Surgery (Anderson Hynes pyeloplasty: A-H pyeloplasty ) can be done with or without (Nephrostomy tube) D-J stent.Here we are describing our comparative experience between A-H pyeloplasty with D-J stent and A-H pyeloplasty with nephrostomy tube, at Bangabandhu Sheikh Mujib Medical University(BSMMU) to show the postoperative advantages of the former over the latter. Objectives: To assess functional outcome after A-H pyeloplasty with or without D-J stent in patients of unilateral hydronephrosis. Post operatively renal function was estimated after 3 months by DTPA renogram. Methods: It was a prospective study at Paediatric Surgery department of Bangabandhu Sheikh Mujib Medical University from April 2009 to October 2010. Twenty eight ( age, sex, side and type of operation matched) patients of unilateral hydronephrosis were included in the study and divided into two Groups: Group A (na =15) and Group B (nb=13) patients who underwent A-H pyeloplasty with D-J stent and A-H pyeloplasty with nephrostomy tube respectively. Child with bilateral hydronephrosis, hydronephrosis with associated anomalies like horseshoe kidney, ectopic kidney, solitary kidney, hydronephrosis with vesico ureteric reflux and redopyeloplasty were excluded in this study. Unpaired “t” test and Chi-square test were used for statistical analysis whereas postoperative hospital stay and renal functional improvement were used as parameters of the study. Results: For study Group A (A-H pyeloplasty with D-J stent) postoperative hospital stay were significantly lesser (P<0.00) than the GroupB ( A-H pyeloplasty with nephrostomy tube). Post operative split renal function and glomerular filtration rate (GFR) in Group A was improved (percentage) than Group B. Conclusion: This study reveals postoperative shorter hospital stay and improved postoperative split renal function in A-H pyeloplasty with D-J stent. DOI: http://dx.doi.org/10.3329/jpsb.v2i1.15159 Journal of Paediatric Surgeons of Bangladesh (2011) Vol. 2 (1): 22-25

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