scholarly journals Psychosocial stress increases testosterone in patients with borderline personality disorder, post-traumatic stress disorder and healthy participants

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Christian E. Deuter ◽  
Moritz Duesenberg ◽  
Julian Hellmann-Regen ◽  
Sophie Metz ◽  
Stefan Roepke ◽  
...  
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Mental Disorders ◽  
Stress Disorder ◽  
Gonadal Hormones ◽  
Borderline Personality ◽  
Adult Women ◽  
Testosterone Metabolism ◽  
Testosterone Secretion ◽  
Healthy Control

Abstract Background The gonadal hormone testosterone not only regulates sexual behavior but is also involved in social behavior and cognition in both sexes. Changes in testosterone secretion in response to stress have been reported. In addition, stress associated mental disorders such as borderline personality disorder (BPD) and posttraumatic stress disorder (PTSD) are characterized by alterations in basal testosterone metabolism. However, testosterone changes to stress have not been investigated in mental disorders such as BPD and PTSD so far. Methods In the study described, we investigated testosterone reactivity to an acute psychosocial stressor, the Trier Social Stress Test (TSST). Our sample consisted of young adult women with BPD (n = 28), PTSD (n = 22) or both disorders (n = 22), and healthy control (n = 51). Based on previous studies on basal testosterone secretion in these disorders, we expected the stress-associated testosterone reactivity to be higher in the BPD group and lower in the PTSD group, when compared to the healthy control group. Results The study could demonstrate an increase in testosterone after acute stress exposure across all groups and independent of BPD or PTSD status. Different possible explanations for the absence of a group effect are discussed. Conclusions From the results of this study, we conclude that stress-related changes in testosterone release are not affected by BPD or PTSD status in a female patient population. This study expands the knowledge about changes in gonadal hormones and stress reactivity in these disorders.

Attentional Bias to Personally Relevant Words in Borderline Personality Disorder is Strongly Related to Comorbid Posttraumatic Stress Disorder

2009 ◽  
Vol 23 (2) ◽  
pp. 141-155 ◽  
Author(s):  
Katja Wingenfeld ◽  
Christoph Mensebach ◽  
Nina Rullkoetter ◽  
Nicole Schlosser ◽  
Camille Schaffrath ◽  
...  
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Posttraumatic Stress ◽  
Attentional Bias ◽  
Stress Disorder ◽  
Borderline Personality

Effects of a modified DBT Skills Group for military personnel and Veterans with OSIs and borderline personality disorder or traits

2021 ◽  
pp. e20190067
Author(s):  
Pamela L. Holens ◽  
Jeremiah N. Buhler ◽  
Stephanie Yacucha ◽  
Alyssa Romaniuk ◽  
Brent Joyal
Keyword(s):  
Mental Health ◽  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Military Personnel ◽  
Group Treatment ◽  
Stress Disorder ◽  
Borderline Personality ◽  
Behaviour Therapy ◽  
Negative Thoughts ◽  
Skills Group

LAY SUMMARY This study looked at the use of a group treatment known as dialectical behaviour therapy skills group (DBT-SG) to see if it was helpful for military personnel and veterans who had a variety of mental health disorders related to their service. The results of the study showed improvements in symptoms of borderline personality disorder, reductions in negative thoughts and feelings, and reductions in unhelpful behaviours. Results also showed improvements in all examined areas of functioning among participants, with the largest change occurring in the area of social functioning. The presence of posttraumatic stress disorder (PTSD), depression, or chronic pain did not impact results, but the presence of a substance abuse disorder did. Overall, the results provide preliminary support for DBT-SG as an intervention for borderline personality disorder symptoms among military and veterans, and perhaps particularly for persons who also have other mental health challenges, or persons considered inappropriate for other treatment.

Emotional intelligence in patients with posttraumatic stress disorder, borderline personality disorder and healthy controls

2018 ◽  
Vol 264 ◽  
pp. 290-296 ◽  
Author(s):  
Katrin Janke ◽  
Martin Driessen ◽  
Behnoush Behnia ◽  
Katja Wingenfeld ◽  
Stefan Roepke
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Emotional Intelligence ◽  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Borderline Personality ◽  
Healthy Controls

Is borderline personality disorder really an emotion dysregulation disorder and, if so, how? A comprehensive experimental paradigm

2020 ◽  
pp. 1-13
Author(s):  
Skye Fitzpatrick ◽  
Sonya Varma ◽  
Janice R. Kuo
Keyword(s):  
Emotion Regulation ◽  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Emotion Dysregulation ◽  
Emotional Reactivity ◽  
Vagal Tone ◽  
Borderline Personality ◽  
Self Report ◽  
Healthy Control ◽  
Emotional Recovery

Abstract Background Leading theories suggest that borderline personality disorder (BPD) is an emotion dysregulation disorder involving lower basal vagal tone, higher baseline emotion, heightened emotional reactivity, delayed emotional recovery, and emotion regulation deficits. However, the literature to date lacks a unifying paradigm that tests all of the main emotion dysregulation components and comprehensively examines whether BPD is an emotion dysregulation disorder and, if so, in what ways. This study addresses the empirical gaps with a unified paradigm that assessed whether BPD is characterized by five leading emotion dysregulation components compared to generalized anxiety disorder (GAD) and healthy control (HC) groups. Methods Emotion was assessed across self-report, sympathetic, and parasympathetic indices. Participants with BPD, GAD, and HCs (N = 120) first underwent baseline periods assessing basal vagal tone and baseline emotional intensity, followed by rejection-themed stressors assessing emotional reactivity. Participants then either reacted normally to assess emotional recovery or attempted to decrease emotion using mindfulness or distraction to assess emotion regulation implementation deficits. Results Individuals with BPD and GAD exhibited higher self-reported and sympathetic baseline emotion compared to HCs. The BPD group also exhibited self-reported emotion regulation deficits using distraction only compared to the GAD group. Conclusions There is minimal support for several emotion dysregulation components in BPD, and some components that are present appear to be pervasive across high emotion dysregulation groups rather than specific to BPD. However, BPD may be characterized by problems disengaging from emotion using distraction.

Complex PTSD – a better description for borderline personality disorder?

2017 ◽  
Vol 25 (4) ◽  
pp. 333-335 ◽  
Author(s):  
Jayashri Kulkarni
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Diagnostic Category ◽  
Borderline Personality ◽  
Complex Posttraumatic Stress Disorder ◽  
Dsm 5 ◽  
Trauma Informed

Objective: To consider the use of the diagnostic category ‘complex posttraumatic stress disorder’ (c-PTSD) as detailed in the forthcoming ICD-11 classification system as a less stigmatising, more clinically useful term, instead of the current DSM-5 defined condition of ‘borderline personality disorder’ (BPD). Conclusions: Trauma, in its broadest definition, plays a key role in the development of both c-PTSD and BPD. Given this current lack of differentiation between these conditions, and the high stigma faced by people with BPD, it seems reasonable to consider using the diagnostic term ‘complex posttraumatic stress disorder’ to decrease stigma and provide a trauma-informed approach for BPD patients.

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