scholarly journals Hepatocellular carcinoma with uncommon sites of metastasis: a rare case report

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Mangala Targe ◽  
Venkata Ramesh Yasam ◽  
Raj Nagarkar
Keyword(s):  
Hepatocellular Carcinoma ◽  
Case Report ◽  
Treatment Planning ◽  
Adrenal Glands ◽  
Extrahepatic Metastasis ◽  
Histopathological Diagnosis ◽  
Axillary Lymph ◽  
Regional Lymph Nodes ◽  
Psoas Muscles ◽  
Right Lobe

Abstract Background Hepatocellular carcinoma (HCC) is a highly malignant tumor, causing both intrahepatic and extrahepatic metastases. The extrahepatic metastasis occurs in one-third of patients with HCC and it is associated with a poor prognosis. The most common sites of extrahepatic metastasis are lung, regional lymph nodes, bone, adrenal glands, and peritoneum/omentum. Detection of such extrahepatic metastasis plays a vital role in the staging and treatment planning of HCC. Case presentation A 60-year-old man was presented to our centre with loss of apetite, generalised weakness, and weight loss. Abdominal examination revealed a firm lump in the right hypochondrium. CT findings revealed a large well-defined hypodense mass in almost entire right lobe of the liver. A well-defined oval, heterogeneously enhancing soft tissue mass lesions were also noted in both adrenal glands and psoas muscles. For histopathological diagnosis, percutaneous ultrasound-guided truecut biopsy was done from right lobe liver mass confirming well differentiated HCC. Conclusions In the present case report, we present an extremely rare and unique case of HCC with disseminated skeletal muscle metastasis with concomitant bilateral axillary lymph node metastasis. It is crucial for radiologists to detect such extrahepatic sites of metastasis initially at the time of diagnosis for accurate staging and treatment planning for a better prognosis.

scholarly journals Cone Beam Computed Tomography Evaluation of the Diagnosis, Treatment Planning, and Long-Term Followup of Large Periapical Lesions Treated by Endodontic Surgery: Two Case Reports

2013 ◽  
Vol 2013 ◽  
pp. 1-12
Author(s):  
Vijay Shekhar ◽  
K. Shashikala
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Treatment Planning ◽  
Cone Beam Computed Tomography ◽  
Cone Beam ◽  
Histopathological Diagnosis ◽  
Periapical Lesions ◽  
Endodontic Surgery ◽  
Anterior Teeth

The aim of this case report is to present two cases where cone beam computed tomography (CBCT) was used for the diagnosis, treatment planning, and followup of large periapical lesions in relation to maxillary anterior teeth treated by endodontic surgery. Periapical disease may be detected sooner using CBCT, and their true size, extent, nature, and position can be assessed. It allows clinician to select the most relevant views of the area of interest resulting in improved detection of periapical lesions. CBCT scan may provide a better, more accurate, and faster method to differentially diagnose a solid (granuloma) from a fluid-filled lesion or cavity (cyst). In the present case report, endodontic treatment was performed for both the cases followed by endodontic surgery. Biopsy was done to establish the confirmatory histopathological diagnosis of the periapical lesions. Long-term assessment of the periapical healing following surgery was done in all the three dimensions using CBCT and was found to be more accurate than IOPA radiography. It was concluded that CBCT was a useful modality in making the diagnosis and treatment plan and assessing the outcome of endodontic surgery for large periapical lesions.

scholarly journals A Case Report of Hepatocellular Carcinoma Associated with Sarcoid Reaction in Regional Lymph Nodes

2007 ◽  
Vol 40 (3) ◽  
pp. 271-276 ◽  
Author(s):  
Soon-Myoung Kang ◽  
Akihiro Murata ◽  
Masatoshi Shibutani ◽  
Seika Tei ◽  
Shinobu Yamada ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Case Report ◽  
Lymph Nodes ◽  
Regional Lymph Nodes ◽  
Sarcoid Reaction

Adenomatoid odontogenic tumour: A rare threat to orthodontic treatment planning

2019 ◽  
Vol 46 (3) ◽  
pp. 259-266
Author(s):  
Laura Han ◽  
Alison Downing ◽  
David Farr ◽  
Kaushik Dasgupta ◽  
Duncan Stewart
Keyword(s):  
Case Report ◽  
Treatment Planning ◽  
Orthodontic Treatment ◽  
Treatment Plan ◽  
Dentigerous Cyst ◽  
Histopathological Diagnosis ◽  
Odontogenic Tumour ◽  
Adenomatoid Odontogenic Tumour

This case report aims to increase awareness of how an adenomatoid odontogenic tumour (AOT) can present in a similar fashion to a dentigerous cyst and the importance of accurate histopathological diagnosis. In this case, the AOT resulted in loss of the upper left permanent canine in a patient who already had a congenitally absent upper left second premolar, compromising the original orthodontic treatment plan.

scholarly journals Undiagnosed Hepatocellular Carcinoma Presenting as Nasal Metastases

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Hassen Mohammed ◽  
Rashid Sheikh ◽  
Waheed Rahman ◽  
Sally Sheta ◽  
Zeynel Dogan
Keyword(s):  
Hepatocellular Carcinoma ◽  
Lymph Nodes ◽  
Rare Case ◽  
Adrenal Glands ◽  
Extrahepatic Metastasis ◽  
Primary Malignancy ◽  
Metastatic Sites

Hepatocellular carcinoma (HCC) is a primary malignancy of the liver with up to half of cases suffering from extrahepatic metastasis in the later stages of the disease. Commonly reported and encountered metastatic sites include the lymph nodes, lung, bone, and adrenal glands. This is an effort to throw a spotlight on a rare case of metastatic HCC which presented to us as two distinct lesions in the nose. It focuses on the presentation and the steps that were taken to reach this rare and unusual diagnosis. It sparks interest from a clinical and histopathology perspective. Our cynosure is the findings of the case coupled with a probe on the possible routes of spread of HCC to sinonasal region.

scholarly journals Extrahepatic metastasis of hepatocellular carcinoma to the paravertebral muscle: A case report

2017 ◽  
Vol 9 (22) ◽  
pp. 973 ◽  
Author(s):  
Kazuhiro Takahashi ◽  
Krishna G Putchakayala ◽  
Mohamed Safwan ◽  
Dean Y Kim
Keyword(s):  
Hepatocellular Carcinoma ◽  
Case Report ◽  
Extrahepatic Metastasis ◽  
Paravertebral Muscle

scholarly journals Hepatic adrenal rest tumor in a patient with multifactorial liver cirrhosis: a case report with CT and MRI findings and pathologic correlation

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Piero Boraschi ◽  
Francesca Turini ◽  
Francescamaria Donati ◽  
Francesca Peruzzi ◽  
Annamaria Bartolucci ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cirrhosis ◽  
Broad Ligament ◽  
Cirrhotic Liver ◽  
Arterial Phase ◽  
Histopathological Diagnosis ◽  
Adrenal Rest Tumor ◽  
Right Lobe ◽  
Adrenal Rest ◽  
The Right

Abstract Background Adrenal rest tumor is an ectopic collection of adrenocortical cells in an extra-adrenal site, more frequently located around the kidney, retroperitoneum, spermatic cord, para-testicular region and broad ligament, but very rarely occurring also in the liver. Hepatic adrenal rest tumor poses a diagnostic challenge in differentiating it from hepatocellular carcinoma, particularly in a cirrhotic liver. Case presentation An 83-years-old male was referred to our hospital by his family doctor for hepatological evaluation due to multifactorial liver cirrhosis. Ultrasound revealed a centimetric hypoechoic nodule in the VI hepatic segment in the context of a liver with signs of cirrhosis and steatosis. The patient first underwent MRI and then CT, which showed a fat containing focal liver lesion in the subcapsular location of the right lobe, strictly adjacent to the homolateral adrenal gland. The nodule was hypervascular in the arterial phase, washed out in the portal-venous and transitional phases, resulting hypointense in the hepato-biliary phase at MR imaging. In the suspicion of a hepatocellular carcinoma, the nodule was surgically removed, and the patient’s postoperative course was unremarkable. The final histopathological diagnosis was of adrenal rest tumor of the liver. Conclusions Hepatic adrenal rest tumor is an extremely rare hepatic tumor, often without any clinical manifestation, that can also occur in the cirrhotic liver as in our case. Although there are not specific imaging findings, the possible diagnosis of HART should be considered when we observe a well-defined lesion in the subcapsular location of the right lobe, with fat containing, hypervascularity after contrast medium injection and vascular supply from the right hepatic artery.

scholarly journals Intraconal Metastasis Leading to Diagnosis of Hepatocellular Carcinoma

2019 ◽  
Vol 12 (1) ◽  
pp. 48-51 ◽  
Author(s):  
Irappa Madabhavi ◽  
Sandeep KS ◽  
Rahul Dharmarajan Lethika ◽  
Satish Tumbal ◽  
Arun T Miskin ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Biopsy Specimen ◽  
Adrenal Glands ◽  
Histopathological Examination ◽  
Definitive Diagnosis ◽  
Orbital Cavity ◽  
Regional Lymph Nodes ◽  
The Third ◽  
Extrahepatic Metastases ◽  
Related Mortality

Hepatocellular carcinoma (HCC) is the commontumor of the liver and the third most common cause of cancer-related mortality worldwide. Patients with HCC may have metastasis to different sites. Intrahepatic and extrahepatic metastases are found in (~50–75%). Lung and regional lymph nodes are the most commonly involved sites. Metastasis to bone, skin, and adrenal glands are rare. Orbit metastasis and intracranial invasion are extremely rare. We are presenting a case of HCC that metastasized to the orbital cavity. The patient presented with progressive proptosis of the eyeball with retrobulbar and intracranial invasion and involvement of the sub-scalp region. Based on the imaging findings, it was initially misdiagnosed as meningioma; however, histopathological examination of the biopsy specimen resulted in a definitive diagnosis of HCC metastasis. The present case reveals that the alternative diagnosis of metastasis must be considered when diagnosing retrobulbar lesions in patients with HCC.

scholarly journals Brain Metastases From Hepatocellular Carcinoma: A Rare Case Report

2020 ◽  
Author(s):  
Parvaneh Dehghan ◽  
Samaneh Kakhki
Keyword(s):  
Hepatocellular Carcinoma ◽  
Brain Metastasis ◽  
Adrenal Glands ◽  
Regional Lymph Nodes ◽  
Metastatic Lesions ◽  
Number Of Patients ◽  
Rare Case Report ◽  
Targeted Drug ◽  
Molecularly Targeted Drug ◽  
The Brain

Intrahepatic lesions of hepatocellular carcinoma (HCC) have been controlled by significant advances in treatment, including chemotherapy, surgery, and ablative therapy. Consequently, the number of patients with extrahepatic metastatic lesions has increased, including lung, regional lymph nodes, peritoneum, and adrenal glands, but rarely to the brain. The prognosis of brain metastasis remains poor, with approximately <1 y of survival from the time of diagnosis. Although no guidelines for the brain metastasis of HCC have been developed to date due to the lack of the experiences and pieces of evidence, a molecularly targeted drug, sorafenib, have been used to treat extrahepatic lesions and shown the prolonged survival time. Therefore, the development of standard therapy for brain metastasis following the early diagnosis is essential by accumulating the information of clinical courses and pieces of evidence.

Sign in / Sign up

Export Citation Format

Share Document