ONS Guidelines™ for Cancer Treatment–Related Hot Flashes in Women With Breast Cancer and Men With Prostate Cancer

The COVID-19 pandemic has an unprecedented impact on cancer treatment worldwide. We aimed to evaluate the effects of the pandemic on the radiation treatment of patients in order to provide data for future management of such crises. We compared the number of performed radiotherapy sessions of the pandemic period from February 2020 until May 2021 with those of 2018 and 2019 for reference. At our department, no referred patients had to be rejected or postponed, nor any significant changes in fractionation schedules implemented. Nevertheless, there was a substantial drop in overall radiotherapy sessions in 2020 following the first incidence wave of up to −25% (in June) in comparison to previous years. For breast cancer, a maximum decline of sessions of −45% (July) was recorded. Only a short drop of prostate cancer sessions (max −35%, May) followed by a rebound (+42%, July) was observed. Over the investigated period, a loss of 4.4% of expected patients never recovered. The severe impact of COVID-19 on cancer treatment, likely caused by retarded diagnosis and delayed interdisciplinary co-treatment, is reflected in a lower count of radiotherapy sessions. Radiation oncology is a crucial cornerstone in upholding both curative treatment options and treatment capacity during a pandemic.

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Pharmacotherapy Options in Cancer Treatment-induced Bone Loss: Focus on Bisphosphonates

Clinical Medicine Therapeutics ◽

10.4137/cmt.s2064 ◽

2009 ◽

Vol 1 ◽

pp. CMT.S2064

Author(s):

Kouta Ito

Keyword(s):

Breast Cancer ◽

Prostate Cancer ◽

Bone Loss ◽

Cancer Survivors ◽

Cancer Treatment ◽

Small Sample ◽

Ablation Therapy ◽

Prostate Cancer Survivors ◽

Hormone Ablation ◽

Hormone Ablation Therapy

Bone loss and its associated risk of fracture is a serious long-term health issue for breast cancer and prostate cancer survivors. Hormone ablation therapy, in particular aromatase inhibitors (AIs) for breast cancer and androgen deprivation therapy (ADT) for prostate cancer, causes marked reduction in circulating estrogen or testosterone levels, resulting in increased bone resorption, decreased bone mineral density (BMD), and an increased risk of fragility fracture. In several clinical trials with small sample sizes and short follow-up periods, oral and intravenous bisphosphonates have been shown to improve BMD, but not actual fracture rates, in cancer patients on hormone ablation therapy. A number of professional organizations and expert panels recommend the use of bisphosphonates for selected patients at risk. Although bisphosphonates are generally well tolerated, physicians should be aware of safety concerns, including the risk of osteonecrosis of the jaw. With the growing number of older breast and prostate cancer survivors, additional research is needed to characterize patients who would benefit from pharmacotherapy and optimize strategies to prevent cancer treatment-induced bone loss.

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Management of hot flashes in breast cancer survivors and men with prostate cancer

Current Oncology Reports ◽

10.1007/s11912-004-0037-y ◽

2004 ◽

Vol 6 (4) ◽

pp. 285-290 ◽

Cited By ~ 11

Author(s):

Vered Stearns

Keyword(s):

Breast Cancer ◽

Prostate Cancer ◽

Cancer Survivors ◽

Breast Cancer Survivors ◽

Hot Flashes

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BIOBOARD

Asia-Pacific Biotech News ◽

10.1142/s0219030311000334 ◽

2011 ◽

Vol 15 (06) ◽

pp. 3-11

Keyword(s):

Breast Cancer ◽

Prostate Cancer ◽

Lung Cancer ◽

Ovarian Cancer ◽

Cancer Treatment ◽

Brain Disorder ◽

Lung Cancer Treatment

AUSTRALIA – Asian Mushrooms Could Help Fight Prostate Cancer AUSTRALIA – New Lung Cancer Treatment Discovered AUSTRALIA – Gene Behind Rare Brain Disorder Identified CHINA – China Bans Controversial Drug for Kids Below 12 INDIA – Ovarian Cancer Treated with Immunotherapy INDIA – Gene Card Tells What Drugs to Avoid INDIA – IISc, Deakin Join Hands to Fight Cancer with Nanotechnology INDIA – Indian Govt to Introduce First Five-in-One Vaccine SINGAPORE – New Test for Pain Tolerence SINGAPORE – NUS Best University for Medicine in Asia OTHER REGIONS — Implant Breakthrough Helps Paraplegic Man Stand Unaided OTHER REGIONS — Scientists Discover Protein that can Halt Spread of Breast Cancer

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The Influence of Breast Cancer Treatment on the Occurrence of Hot Flashes

Journal of Pain and Symptom Management ◽

10.1016/j.jpainsymman.2008.04.010 ◽

2009 ◽

Vol 37 (4) ◽

pp. 687-697 ◽

Cited By ~ 26

Author(s):

Marie-Hélène Savard ◽

Josée Savard ◽

Catherine Quesnel ◽

Hans Ivers

Keyword(s):

Breast Cancer ◽

Cancer Treatment ◽

Hot Flashes ◽

Breast Cancer Treatment

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Provider-Level Factors Influencing Implementation

10.1093/med/9780190647421.003.0016 ◽

2018 ◽

Author(s):

Alex H. Krist ◽

Vivian Jiang

Keyword(s):

Breast Cancer ◽

Prostate Cancer ◽

Cancer Treatment ◽

Low Income ◽

Treatment Modalities ◽

Shared Decision ◽

Prostate Cancer Treatment ◽

Treatment Protocols ◽

Patient Level ◽

Factors Influencing

Cancer treatment is increasingly complex. The tools for diagnosis, staging, and predicting prognosis are rapidly evolving, as are the therapies, treatment modalities, and treatment protocols. The complexity of care, the need for a multidisciplinary team across settings, and patient-level factors all present providers with a unique set of challenges. The three case studies presented in this chapter explore strategies that help providers by (1) ensuring low-income patients with breast cancer receive care consistent with guidelines through patient engagement and navigation, (2) promoting and incorporating the routine use of shared decision-making in determining prostate cancer treatment, and (3) supporting the adoption of concurrent palliative care for patients with advanced cancer. The specific challenges and needs for future implementation science are highlighted throughout each case.

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