Comparative Hypnotic Efficacy of “Phenaglate”

1960 ◽  
Vol 106 (443) ◽  
pp. 675-678 ◽  
Author(s):  
M. D. Eilenberg ◽  
I. Lodge Patch ◽  
E. H. Hare

The widespread use of barbiturates as hypnotics for insomnia has greatly increased the risk of accidental overdosage and the number of suicidal attempts. The size of the problem concerning barbiturates and suicidal attempts is difficult to estimate as only suicidal deaths are recorded by the Registrar General, and his statistics for 1956 (R.G., 1958) reveal that out of a total of 5,282 suicidal deaths, drugs (mainly barbiturates) were second only to domestic coal gas poisoning as the effective agent. Stengel (1958) calculated that six times the number of suicidal deaths gives an approximate estimate of the number of attempted suicides. Locket and Angus (1952) found that of the patients admitted to their Unit, barbiturates were the drug involved in 80 per cent. of the cases and that in 90 per cent. of the cases it had been prescribed for the treatment of insomnia. Locket (1958) also estimated that some 6,000 patients were admitted annually to hospitals in England and Wales for treatment of barbiturate poisoning.

1950 ◽  
Vol 96 (405) ◽  
pp. 1015-1023 ◽  
Author(s):  
G. D. F. Steele ◽  
A. B. Hegarty

Suicidal attempts by coal-gas poisoning are very common. Carbon monoxide is a principal constituent of this gas, and can produce severe and permanent brain damage. It is surprising, therefore, to find so few cases of chronic organic psychosis attributed to this cause in mental hospital practice. Rosseter (1928) found only one example of permanent psychosis in 2,000 cases of carbon monoxide asphyxiation. Shillito, Drinker and Shaughnessy (1936) made a follow-up study of 21,000 cases of acute carbon monoxide poisoning. In only 43 of these were the after-effects sufficiently severe to warrant their admission to a mental hospital. Twenty-three subsequently recovered, 11 died, and 9 suffered permanent nervous and mental sequelae. They found that the ratio of psychosis following carbon monoxide poisoning to other psychoses was 1 in 2,000. Henderson and Gillespie (1944) could find only one such case in 5,000 consecutive admissions.


BMJ ◽  
1955 ◽  
Vol 2 (4937) ◽  
pp. 490-490
Author(s):  
V. Biske
Keyword(s):  
Coal Gas ◽  

1911 ◽  
Vol 5 ◽  
pp. 1-86
Author(s):  
James Craufurd Dunlop

Mr. President,—It is in response to your invitation that I venture to submit to this Faculty a paper on the Influence of Occupation on Mortality. I have no fresh statistical observations to lay before you, but the task I have set myself is to elaborate the observations set out in the Supplement to the Registrar-General of England and Wales' Sixty-fifth Report, part II., a report which was published early this year. That report may rightly be described as the most important contribution to our knowledge of the subject which has yet been published, and it is thanks to the excellent tabulation of facts in it that I am able to deal further with them.Before asking your attention to the subject proper of my paper, an examination of the results of the recent English study, I desire briefly to describe previous statistical observations on the subject, to indicate to you some of the difficulties and limitations in drawing satisfactory conclusions from these studies, and to explain the methods which have previously been used to overcome these difficulties, and methods which I now use for the first time.


1881 ◽  
Vol 105 (2) ◽  
pp. 29-32
Author(s):  
HERBERT TERRY
Keyword(s):  
Coal Gas ◽  

1931 ◽  
Vol 31 (3) ◽  
pp. 406-413 ◽  
Author(s):  
W. T. Russell

That the number of deaths ascribed to cancer has steadily increased within recent years no one will deny, but as to the causes which have produced the increase there is not the same unanimity of opinion. Thirty years ago cancer did not rank very high in the list of fatal diseases. In 1899 the total number of deaths from cancer amongst persons in England and Wales was 26,325 as against 60,659 allocated to tubercular disease. Nowadays, “the old order changeth yielding place to new.” According to the most recent statistics issued by the Registrar-General, in 1929, the number of deaths assigned to cancer was 56,896 and to all forms of tuberculosis 37,990. In view of this large increase in the number of deaths allocated to cancer it seemed of interest to review the cancer statistics of the last thirty years in this country and in Scotland. No investigation of this nature would be complete without first drawing attention to the very important work already done by Dr Stevenson in the Annual Reports of the Registrar-General, particularly the report for 1917 in which he examined the incidence of cancer in particular sites. The statistics of cancer in Scotland have not, until recently, received quite the same amount of attention as those of England. In a paper read to the Medical Association in Edinburgh and afterwards published in the Journal of that society, Dr Dunlop, the Registrar-General, gave a detailed account of the mortality, according to sites, between the years 1911 and 1928. He compared the actual numbers of deaths in 1920–2 and in 1928 with the numbers that might be expected to occur on the basis of the cancer mortality in age groups which prevailed in 1910–12. His method of analysis conforms partly to that of indirect standardisation.


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