The Clinical Evaluation of Unilateral Electroconvulsive Therapy

1968 ◽  
Vol 114 (509) ◽  
pp. 459-463 ◽  
Author(s):  
Raymond Levy∗
Keyword(s):  
Clinical Evaluation ◽  
Electroconvulsive Therapy ◽  
Recent Advances ◽  
Treatment Of Depression ◽  
Selection Of Patients ◽  
Selection Of

Electroconvulsive therapy (E.C.T.), first introduced in 1937, rapidly became accepted as playing an important part in the treatment of depression. Since its introduction, there have been few modifications of the technique that have stood the test of time. The most important has been the use of muscular relaxants to modify the convulsion. Most recent advances have been directed towards the development of reliable criteria for the selection of patients most likely to respond to treatment, but little attention has been paid to improvements in the method of treatment as such.

scholarly journals CLINICAL EVALUATION OF MATRA BASTI OF VARUN TAILA AND KANCHNAR GUGGULU IN VATASTHEELA (BPH)

2021 ◽  
Vol 9 (11) ◽  
pp. 2671-2677
Author(s):  
Amit Kumar Gautam ◽  
Kainat Ansari ◽  
Ketan Mahajan ◽  
Sachin Gupta
Keyword(s):  
Clinical Evaluation ◽  
Daily Routine ◽  
Research Committee ◽  
Exclusion Criteria ◽  
Treat Ment ◽  
Routine Work ◽  
Before And After ◽  
Marked Relief ◽  
Selection Of Patients ◽  
Selection Of

Background and Objective: BPH is a senile disorder, which leads to urinary symptoms like incomplete empty- ing, urgency etc. 90 % of the males over 80 years of age have histological evidence of BPH. Acharya Sushruta has described Vatastheela, as a type of Mutraghata. Owing to the various medical and surgical complications while treating the disease, an Ayurvedic approach using classical medicines in the management of BPH is re- quired. This study was conducted clinical evaluation of Matra Basti of Varun Taila and Kanchnar Guggulu in Vatastheela (BPH). Aim: In this clinical study the aim was to evaluate the effects of Matra Basti of Varun Taila and Kanchnar Guggulu in the management of Vatastheela (BPH). Material and Methods: Random selection of patients was done from OPD of Shalya Tantra Patanjali Ayurved Hospital Haridwar. The study is approved by the ethics and research committee of the same institute vide its latter no PAC/IEC/2018-19/04 and CTRI Registrationnumber CTRI/ 2020/11/029404. Based on the Inclusion and exclusion criteria a total of 30 patients were selected. Kanchnar Guggulu 2 TAB BD for 3 months and Varun Talia 72 ml Matra Basti for 1week. Observation: As- sessment was made on subjective and objective parameters. Observations were recorded before and after treat- ment. The grading of parameters was used for statistical analysis. Results: The results showed marked relief in subjective and objective parameters. Moreover, this therapy was well accepted by all patients and did not cause any hindrance in their daily routine work during period of management. Conclusion: We can conclude that the effects of Matra Basti of Varun Taila and Kanchnar Guggulu were significant and free from any complication. Since this study was on small size sample further evaluation is needed to be done and study should be repeated with large sample for longer duration for its establishment. Keywords: Varun Taila, Kanchnar Guggulu, Vatastheela, BPH.

Electroconvulsive Therapy and Depression

1965 ◽  
Vol 111 (477) ◽  
pp. 687-690 ◽  
Author(s):  
J. Mendels
Keyword(s):  
Electroconvulsive Therapy ◽  
Clinical Picture ◽  
Antidepressant Drugs ◽  
Convulsive Therapy ◽  
Depressed Patients ◽  
Treatment Of Depression ◽  
Electro Convulsive Therapy ◽  
Selection Of

After 25 years there is still considerable disagreement surrounding the indications for electro-convulsive therapy (E.C.T.). This is a particular problem in the treatment of depression, both because of the controversy over the division of depression into endogenous and reactive illnesses and because of the increasing use of the antidepressant drugs. These drugs will induce a remission in many patients, and will alter the clinical picture in others. As their use becomes still more widespread (Freyhan (1) has recommended that intensive imipramine treatment should be tried routinely before E.C.T. in all depressed patients) there may be further difficulties in the selection of depressed patients likely to respond well to E.C.T. Furthermore several recent reviews draw attention to a reduction in the use of E.C.T., and the lack of a consistent rationale for its use (2–4).

Selection of patients for portal-systemic shunts

JAMA ◽  
1966 ◽  
Vol 196 (12) ◽  
pp. 1039-1044 ◽  
Author(s):  
R. E. Hermann
Keyword(s):  
Selection Of Patients ◽  
Selection Of

Perioperative acute internal carotid thrombosis after general surgery

2020 ◽  
Vol 99 (3) ◽  
pp. 136-140
Keyword(s):  
Cardiac Surgery ◽  
Internal Carotid ◽  
Right Hemicolectomy ◽  
Diagnostic Assessment ◽  
Left Carotid Artery ◽  
Perioperative Stroke ◽  
Internal Carotid Occlusion ◽  
Acute Brain Ischemia ◽  
Selection Of Patients ◽  
Selection Of

Introduction: The average incidence of perioperative stroke during major non-cardiac surgery is less than 1%, suggesting that it is rarely a major problem for the vast majority of patients. Methods: In our paper we present a 46-year-old patient undergoing acute right hemicolectomy who developed right-sided hemiparesis in the perioperative setting. Immediate CTAg examination showed an ischemic stroke in the left hemisphere as a result of left internal carotid thrombosis. A surgical procedure to recanalize the left carotid artery was performed 14 hours from the onset of neurological symptomatology and the neurological deficit gradually recovered fully. Conclusion: Our case report supports studies showing that a thorough diagnostic assessment allows the selection of patients who may benefit from urgent revascularization of acute internal carotid occlusion during the phase of acute brain ischemia.

Recent advances on the synthesis of the antidepressant Paroxetine

2020 ◽  
Vol 27 ◽  
Author(s):  
Joana Santos ◽  
M. Fernanda Proença ◽  
Ana Joao Rodrigues ◽  
Patricia Patrício ◽  
H. Sofia Domingues
Keyword(s):  
Total Synthesis ◽  
Neurological Disorders ◽  
Serotonin Reuptake ◽  
Potent Inhibitor ◽  
Starting Material ◽  
Substitution Pattern ◽  
Biological Probes ◽  
Recent Advances ◽  
Treatment Of Depression ◽  
Made In

: Paroxetine is a potent inhibitor of serotonin reuptake and is widely prescribed for the treatment of depression and other neurological disorders. The synthesis of paroxetine and the possibility to prepare derivatives with a specific substitution pattern that may allow their use as biological probes, is an attractive topic especially for medicinal chemists engaged in neurosciences research. Considering the extensive work that was developed in the last decade on the total synthesis of paroxetine, this review summarizes the most important contributions in this field, organized according to the reagent that was used as starting material. Most of the methods allowed to prepare paroxetine in 4-9 steps with an overall yield of 9-66%. Despite the progress made in this area, there is still room for improvement, searching for new eco-friendly and sustainable synthetic alternatives.

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