Growth Hormone Response to Clonidine in Obsessive-Compulsive Patients
1983 ◽
Vol 142
(2)
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pp. 184-187
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Keyword(s):
SummaryWe have observed a lesser growth hormone response to intravenous clonidine administration in nine obsessive-compulsive disorder patients meeting research diagnostic criteria than in nine matched controls. The obsessive-compulsive disorder patients had higher plasma free 3-methoxy-4-hydroxyphenylglycol and plasma norepinephrine levels before clonidine than the controls. As blunted growth hormone responses to clonidine are also characteristic of affective disorder patients, these results support other observations of a psychobiologic affinity between these two groups and are also compatible with an association between increased presynaptic noradrenergic activity and decreased post-synaptic receptor responsiveness.
1998 ◽
Vol 81
(3)
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pp. 293-299
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1997 ◽
Vol 42
(10)
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pp. 889-897
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1992 ◽
Vol 86
(5)
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pp. 367-370
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1993 ◽
Vol 150
(6)
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pp. 961-962
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2002 ◽
Vol 59
(2)
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pp. 186-187
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1985 ◽
Vol 142
(3)
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pp. 358-360
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1999 ◽
Vol 45
(5)
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pp. 615-619
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1999 ◽
Vol 24
(2)
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pp. 143-153
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