Pre-Pubertal Depressive Stupor: A Case Report

1988 ◽  
Vol 153 (5) ◽  
pp. 689-692 ◽  
Author(s):  
J. C. Powell ◽  
W. R. Silveira ◽  
R. Lindsay
Keyword(s):  
Case Report ◽  
Family History ◽  
Affective Disorder ◽  
Dexamethasone Suppression Test ◽  
Clinical State ◽  
Affective Illness ◽  
History Of ◽  
Suppression Test ◽  
Dexamethasone Suppression ◽  
Maternal Side

A case of childhood affective disorder with episodes of depressive stupor in a 13-year-old pre-pubertal boy is described. Changes in the patient's clinical state were accompanied by changes in the dexamethasone suppression test. A family history of affective illness on the maternal side, with phenomenological similarities, is noted.

scholarly journals Are Dexamethasone Suppression Test Nonsuppression and Thyroid Dysfunction Related to a Family History of Dementia in Patients with Major Depression? An Exploratory Study

2005 ◽  
Vol 50 (6) ◽  
pp. 342-345 ◽  
Author(s):  
Konstantinos N Fountoulakis ◽  
Stergios G Kaprinis ◽  
Apostolos Iacovides ◽  
Konstantinos Phokas ◽  
George Kaprinis
Keyword(s):  
Family History ◽  
Major Depression ◽  
Serum Levels ◽  
Thyroid Stimulating Hormone ◽  
Dexamethasone Suppression Test ◽  
Analysis Of Covariance ◽  
Free T4 ◽  
History Of ◽  
Suppression Test ◽  
Dexamethasone Suppression

Objective: Recent data suggest that the low thyroid function syndrome in depression is nonspecific, They also suggest that depression may constitute a risk factor for the development of dementia, especially in atypical patients who have high rates of hypothalamo–pituitary–adrenal axis disorders. This study aimed to search for correlations among Dexamethasone Suppression Test (DST) cortisol levels, thyroid indices, and family history of dementia in patients with depression. Methods: A sample of 30 patients, aged 21 to 60 years and suffering from major depression according to DSM-IV criteria, took part in the study. Three had a family history of dementia in first-degree relatives. We measured their serum levels of free T3, free T4, thyroid-stimulating hormone, thyroid binding inhibitory immunoglobulines, thyroglobulin antibodies, and thyroid microsomal antibodies (TMAs). We applied the 1-mg DST to all patients. The statistical analysis included 1-way multivariate analysis of covariance using t tests as the post hoc tests. Results: Significantly higher levels of TMAs were found in patients with a family history of dementia, compared with those who did not have this family history. Conclusion: The results of this study suggest that a more pronounced autoimmune process may characterize depression patients with a family history of dementia.

Biochemically silent phaeochromocytoma presenting with non-specific loin pain

2021 ◽  
Vol 14 (8) ◽  
pp. e244258
Author(s):  
Annalisa Montebello ◽  
Etienne Ceci Bonello ◽  
Miriam Giordano Imbroll ◽  
Mark Gruppetta
Keyword(s):  
Adrenal Adenoma ◽  
Dexamethasone Suppression Test ◽  
Adrenal Lesion ◽  
Genetic Mutations ◽  
Large Size ◽  
History Of ◽  
Loin Pain ◽  
Suppression Test ◽  
Aldosterone To Renin Ratio ◽  
Dexamethasone Suppression

A 55-year-old woman presented with a 4-month history of right-sided non-specific loin pain and 6 kg weight loss. A CT scan of the abdomen and pelvis showed an incidental 4.5 cm right-sided adrenal lesion which was not typical of an adrenal adenoma. This was further confirmed on MRI of the adrenals. Biochemical investigations to investigate for a functional adrenal lesion included serum catecholamines and metanephrines, an aldosterone to renin ratio and an overnight dexamethasone suppression test. These were all negative. A laparoscopic adrenalectomy was performed in view of the large size of the lesion. Histology was consistent with a phaeochromocytoma, which confirmed the diagnosis of a non-secreting phaeochromocytoma. Non-secreting phaeochromocytomas are rare and usually found in patients with known genetic mutations. Adrenal lesions not related to any mutations similar to our case are even rarer and reported even less in the literature.

Sleep, dexamethasone suppression test, and response to somatic therapies in an atypical affective state presenting as erotomania: a case report

1991 ◽  
Vol 6 (5) ◽  
pp. 269-271
Author(s):  
L Staner
Keyword(s):  
Case Report ◽  
Affective State ◽  
Dexamethasone Suppression Test ◽  
Depressive State ◽  
Suppression Test ◽  
Somatic Therapies ◽  
Dexamethasone Suppression

SummaryThe case of a woman presenting erotomania in the course of a loss-related depressive state is described. Clinical, biological and therapeutical characteristics highlight the role of mood in certain cases of erotomania and add support to previous accounts of the heterogeneity of this syndrome.

The Use of the Dexamethasone Suppression Test in the Differential Diagnosis of Catatonic Stupor

1983 ◽  
Vol 12 (2) ◽  
pp. 93-101 ◽  
Author(s):  
Ronald C. Bloodworth
Keyword(s):  
Affective Disorder ◽  
Affective Disorders ◽  
Dexamethasone Suppression Test ◽  
Psychiatric Institute ◽  
Disease Entity ◽  
Conversion Disorders ◽  
Catatonic Schizophrenia ◽  
Organic Brain ◽  
Suppression Test ◽  
Dexamethasone Suppression

Catatonic stupor is a cluster of symptoms and not necessarily a disease entity. It may be seen not only in schizophrenia, but in major affective disorders, conversion disorders, organic brain syndromes, and atypical psychoses. The dexamethasone suppression test is a valuable tool in the diagnosis of major affective disorders, differentiating them from other types of psychopathology. In a twelve month retrospective study, five patients admitted to Psychiatric Institute of Atlanta were identified as meeting the criteria for catatonic schizophrenia. A dexamethasone suppression test was performed shortly after admission. Four of the five had patterns of inadequate suppression, indicative of a major affective disorder rather than a schizophrenic disorder. The dexamethasone suppression test is simple to administer, relatively painless, free from hazards, easy to interpret, readily available, and reliable. Not only can the dexamethasone suppression test be used in diagnosis, but also as a valuable aid in following the therapeutic progress in resolution of a major affective disorder.

The dexamethasone suppression test in seasonal affective disorder

1986 ◽  
Vol 27 (3) ◽  
pp. 224-226 ◽  
Author(s):  
Steven P. James ◽  
Thomas A. Wehr ◽  
David A. Sack ◽  
Barbara L. Parry ◽  
Susan Rogers ◽  
...  
Keyword(s):  
Affective Disorder ◽  
Seasonal Affective Disorder ◽  
Dexamethasone Suppression Test ◽  
Suppression Test ◽  
Dexamethasone Suppression

Agenesis of the corpus callosum and schizophrenia: a case report

1988 ◽  
Vol 18 (2) ◽  
pp. 341-347 ◽  
Author(s):  
S. W. Lewis ◽  
M. A. Reveley ◽  
A. S. David ◽  
M. A. Ron
Keyword(s):  
Case Report ◽  
Family History ◽  
Corpus Callosum ◽  
Affective Disorder ◽  
Causal Inferences ◽  
History Of ◽  
Neuropsychological Findings

SynopsisClinical, radiological and neuropsychological findings in the first reported case of schizophrenia with complete agenesis of the corpus callosum are described. Although causal inferences were made difficult by the co-existence of a left frontotemporal cyst and a family history of affective disorder, some theories of the role of callosal dysfunction in schizophrenia require revision in the light of this case.

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