Hypothalamic-pituitary-adrenal axis response in borderline personality disorder without post-traumatic features
2007 ◽
Vol 190
(4)
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pp. 357-358
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Keyword(s):
SummaryHypothalamic–pituitary–adrenal (HPA) axis sensitivity was investigated in 32 non-medicated patients with borderline personality disorder without comorbid post-traumatic syndromes and in 18 normal individuals using a modified dexamethasone suppression test (0.25 mg). Enhanced cortisol suppression was found in the patients v. controls (P < 0.05) and the percentage of participant's with non-suppression was smaller in the patient (34%) than in the control group (89%) (P < 0.01). Baseline cortisol levels in the patients were also lower than in the controls (P < 0.05). The 0.25 mg dexamethasone suppression test reveals increased feedback inhibition of the HPA in borderline personality disorder.
2007 ◽
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pp. 843-850
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2005 ◽
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pp. 919-923
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1997 ◽
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pp. 459-464
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1984 ◽
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1993 ◽
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2020 ◽
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pp. 394-409
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