scholarly journals Surfactant lipids regulate LPS-induced interleukin-8 production in A549 lung epithelial cells by inhibiting translocation of TLR4 into lipid raft domains

2009 ◽  
Vol 51 (2) ◽  
pp. 334-344 ◽  
Author(s):  
Wondwossen Abate ◽  
Abdulaziz A. Alghaithy ◽  
Joan Parton ◽  
Kenneth P. Jones ◽  
Simon K. Jackson
Author(s):  
Samu Luostarinen ◽  
Mari Hämäläinen ◽  
Noriyuki Hatano ◽  
Katsuhiko Muraki ◽  
Eeva Moilanen

2015 ◽  
Vol 17 (10) ◽  
Author(s):  
David M. Brown ◽  
Julia Varet ◽  
Helinor Johnston ◽  
Alison Chrystie ◽  
Vicki Stone

Life Sciences ◽  
2001 ◽  
Vol 69 (11) ◽  
pp. 1333-1344 ◽  
Author(s):  
Horng-Chyuan Lin ◽  
Chun-Hua Wang ◽  
Chih-Teng Yu ◽  
Kuo-Shiung Hwang ◽  
Han-Pin Kuo

2019 ◽  
Vol 144 (1) ◽  
pp. 312-315.e1 ◽  
Author(s):  
John T. Schroeder ◽  
Abiodun A. Adeosun ◽  
Danh Do ◽  
Anja P. Bieneman

2013 ◽  
Vol 8 (9) ◽  
pp. 1934578X1300800
Author(s):  
Jung-Taek Kwon ◽  
Mimi Lee ◽  
Gun-Baek Seo ◽  
Hyun-Mi Kim ◽  
Ilseob Shim ◽  
...  

This study evaluated the cytotoxicity of mixtures of citral (CTR) and either benzisothiazolinone (BIT, Mix-CTR-BIT) or triclosan (TCS, Mix-CTR-TCS) in human A549 lung epithelial cells. We investigated the effects of various mix ratios of these common air freshener ingredients on cell viability, cell proliferation, reactive oxygen species (ROS) generation, and DNA damage. Mix-CTR-BIT and Mix-CTR-TCS significantly decreased the viability of lung epithelial cells and inhibited cell growth in a dose-dependent manner. In addition, both mixtures increased ROS generation, compared to that observed in control cells. In particular, cell viability, growth, and morphology were affected upon increase in the proportion of BIT or TCS in the mixture. However, comet analysis showed that treatment of cells with Mix-CTR-BIT or Mix-CTR-TCS did not increase DNA damage. Taken together, these data suggested that increasing the content of biocides in air fresheners might induce cytotoxicity, and that screening these compounds using lung epithelial cells may contribute to hazard assessment.


Cytokine ◽  
2002 ◽  
Vol 20 (6) ◽  
pp. 283-288 ◽  
Author(s):  
Ki-Bae Kim ◽  
Yun-Hee Choi ◽  
In-Ki Kim ◽  
Chul-Woong Chung ◽  
Byung Ju Kim ◽  
...  

2020 ◽  
Vol 11 (6) ◽  
Author(s):  
Gracemary L. R. Yap ◽  
Karishma Sachaphibulkij ◽  
Sok Lin Foo ◽  
Jianzhou Cui ◽  
Anna-Marie Fairhurst ◽  
...  

2007 ◽  
Vol 7 (1) ◽  
pp. 102 ◽  
Author(s):  
Hiromitsu Teruya ◽  
Futoshi Higa ◽  
Morikazu Akamine ◽  
Chie Ishikawa ◽  
Taeko Okudaira ◽  
...  

2002 ◽  
Vol 26 (1) ◽  
pp. 58-66 ◽  
Author(s):  
Kristin R. Coulter ◽  
Andrea Doseff ◽  
Patricia Sweeney ◽  
Yijie Wang ◽  
Clay B. Marsh ◽  
...  

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