Fatal Case of Brazilian Spotted Fever Confirmed by Immunohistochemical Staining and Sequencing Methods on Fixed Tissues

2006 ◽  
Vol 1078 (1) ◽  
pp. 257-259 ◽  
Author(s):  
T. ROZENTAL ◽  
M. E EREMEEVA ◽  
C. D PADDOCK ◽  
S. R ZAKI ◽  
G. A DASCH ◽  
...  
Keyword(s):  
Immunohistochemical Staining ◽  
Spotted Fever ◽  
Fatal Case ◽  
Brazilian Spotted Fever

scholarly journals A fatal case of Brazilian spotted fever in a non-endemic area in Brazil: the importance of having health professionals who understand the disease and its areas of transmission

2016 ◽  
Vol 49 (5) ◽  
pp. 653-655 ◽  
Author(s):  
Stefan Vilges de Oliveira ◽  
Eduardo Pacheco de Caldas ◽  
Silvia Colombo ◽  
Gilberto Salles Gazeta ◽  
Marcelo Bahia Labruna ◽  
...  
Keyword(s):  
Health Professionals ◽  
Endemic Area ◽  
Spotted Fever ◽  
Fatal Case ◽  
Brazilian Spotted Fever

A cluster ofRickettsia rickettsiiinfection at an animal shelter in an urban area of Brazil

2014 ◽  
Vol 143 (11) ◽  
pp. 2446-2450 ◽  
Author(s):  
T. ROZENTAL ◽  
M. S. FERREIRA ◽  
R. GOMES ◽  
C. M. COSTA ◽  
P. R. A. BARBOSA ◽  
...  
Keyword(s):  
Urban Area ◽  
Spotted Fever ◽  
Fatal Case ◽  
Febrile Illness ◽  
Spotted Fever Group ◽  
Animal Shelter ◽  
Rickettsia Rickettsii ◽  
Occupationally Exposed ◽  
Tick Borne Disease ◽  
Brazilian Spotted Fever

SUMMARYRickettsia rickettsiiinfection is being increasingly recognized as an important cause of fatal acute illness in Brazil, where this tick-borne disease is designated Brazilian spotted fever (BSF). In this study we report five fatal cases of BSF in employees of an animal shelter in an urban area in the municipality of Rio de Janeiro in southeast Brazil after a natural disaster on 11 January 2011. Four of the cases occurred from 27 January to 11 April 2011, while the fifth fatal case was identified in April 2012. Three cases were confirmed by molecular analysis and two by epidemiological linkage. An investigation of BSF was performed in the animal shelter, and blood samples were collected from 115 employees and 117 randomly selected dogs. The presence of high levels (1024–4096) of antibodies against spotted fever group rickettsiae was found in three (2·6%) employees and 114 (97·5%) dogs. These findings emphasize the need to consider BSF as a possible cause of undifferentiated febrile illness, especially dengue and leptospirosis, in patients occupationally exposed to dogs heavily infested by ticks, mainly working at kennels and animal shelters that have inadequate space for the animals housed and frequently providing an environment conducive to exposure to pathogens such asR. rickettsii.

scholarly journals Fatal Brazilian spotless fever caused by Rickettsia rickettsii in a dark-skinned patient

2011 ◽  
Vol 44 (3) ◽  
pp. 395-396 ◽  
Author(s):  
Alexsandra Rodrigues de Mendonça Favacho ◽  
Tatiana Rozental ◽  
Simone Berger Calic ◽  
Maria Aparecida Mota Scofield ◽  
Elba Regina Sampaio de Lemos
Keyword(s):  
Abdominal Pain ◽  
Skin Rash ◽  
Spotted Fever ◽  
Fatal Case ◽  
Empirical Therapy ◽  
Severe Headache ◽  
Rickettsial Disease ◽  
Rickettsia Rickettsii ◽  
Black Patients ◽  
Brazilian Spotted Fever

Brazilian spotted fever (BSF) is the most important and frequent rickettsial disease in Brazil. A fatal case of BSF is reported in a 32-year-old black man, who died of irreversible shock after five days of fever, severe headache and abdominal pain with no rash. Spleen, kidney and heart samples collected at autopsy were positive for Rickettsia rickettsii by PCR and sequencing. The authors emphasize the need for a high index of diagnostic suspicion for spotted fever in black patients. Absence of a skin rash should not dissuade clinicians from considering the possibility of BSF and initiating empirical therapy.

scholarly journals Fatal Case of Israeli Spotted Fever after Mediterranean Cruise

2008 ◽  
Vol 14 (12) ◽  
pp. 1944-1946 ◽  
Author(s):  
Noémie Boillat ◽  
Blaise Genton ◽  
Valérie D’Acremont ◽  
Didier Raoult ◽  
Gilbert Greub
Keyword(s):  
Spotted Fever ◽  
Fatal Case

scholarly journals Serosurvey of Rickettsia spp. in dogs and humans from an endemic area for Brazilian spotted fever in the State of São Paulo, Brazil

2008 ◽  
Vol 24 (2) ◽  
pp. 247-252 ◽  
Author(s):  
Adriano Pinter ◽  
Maurício C. Horta ◽  
Richard C. Pacheco ◽  
Jonas Moraes-Filho ◽  
Marcelo B. Labruna
Keyword(s):  
Human Serum ◽  
Endemic Area ◽  
Spotted Fever ◽  
Sao Paulo ◽  
The State ◽  
The Other ◽  
São Paulo ◽  
Human Sera ◽  
Antibody Titers ◽  
Brazilian Spotted Fever

The present study provides a rickettsial serosurvey in 25 dogs and 35 humans in an endemic area for Brazilian spotted fever in the State of São Paulo, where the tick Amblyomma aureolatum is the main vector. Testing canine and human sera by indirect immunofluorescence against four Rickettsia antigens (R. rickettsii, R. parkeri, R. felis and R. bellii) showed that 16 (64%) of canine sera and 1 (2.8%) of human sera reacted to at least one of these rickettsial antigens with titers <FONT FACE=Symbol>³</FONT> 64. Seven canine sera and the single reactive human serum showed titers to R. rickettsii at least four times those of any of the other three antigens. The antibody titers in these 7 animals and 1 human were attributed to stimulation by R. rickettsii infection. No positive canine or human serum was attributed to stimulation by R. parkeri, R. felis, or R. bellii. Our serological results showed that dogs are important sentinels for the presence of R. rickettsii in areas where the tick A. aureolatum is the main vector of Brazilian spotted fever.

scholarly journals Epidemiological aspects of the Brazilian spotted fever: serological survey of dogs and horses in an endemic area in the State of São Paulo, Brazil

1996 ◽  
Vol 38 (6) ◽  
pp. 427-430 ◽  
Author(s):  
Elba R.S. de Lemos ◽  
Raimundo D. Machado ◽  
José R. Coura ◽  
Maria A.A.M. Guimarães ◽  
Nelson Chagas
Keyword(s):  
Endemic Area ◽  
Spotted Fever ◽  
Domestic Animals ◽  
Sao Paulo ◽  
Spotted Fever Group ◽  
São Paulo ◽  
Serological Survey ◽  
Serum Samples ◽  
Blood Samples ◽  
Brazilian Spotted Fever

In order to obtain information on Brazilian spotted fever, a study in domestic animals was performed in the County of Pedreira, State of São Paulo, Brazil, where 17 human cases had been notified. Serum samples obtained from animals were tested by indirect immunofluorescence for detectable antibodies to spotted fever-group rickettsiae. Seropositivity was revealed in 12 (36.4%) of 33 dogs and seven (77.8%) of nine horses from the endemic area. For comparison, blood samples from dogs and horses from non endemic area were tested and four (12.9%) of 31 dogs and three (27.3%) of 11 horses were positive. The highest titers of antibodies by IFA (IgG > 1:1024) were found only in three dogs and six horses from endemic area. The results suggest that dogs as horses may serve as environmental sentinels for estabilishing the prevalence of foci of spotted fever in Brazil.

scholarly journals A new focus of Brazilian spotted fever in the central-west region of São Paulo state, Brazil

2021 ◽  
Vol 54 ◽  
Author(s):  
Felipe Fornazari ◽  
Cristianne Dantas Freirias ◽  
Heloísa Coppini de Lima ◽  
Mauricio Mariani Rodrigues ◽  
Helio Langoni ◽  
...  
Keyword(s):  
Spotted Fever ◽  
Sao Paulo ◽  
São Paulo ◽  
Paulo State ◽  
West Region ◽  
São Paulo State ◽  
Brazilian Spotted Fever

Brazilian Spotted Fever: A Case Series from an Endemic Area in Southeastern Brazil: Epidemiological Aspects

2006 ◽  
Vol 1078 (1) ◽  
pp. 170-172 ◽  
Author(s):  
R. N ANGERAMI ◽  
M. R RESENDE ◽  
A. F.C FELTRIN ◽  
G. KATZ ◽  
E. M NASCIMENTO ◽  
...  
Keyword(s):  
Endemic Area ◽  
Spotted Fever ◽  
Case Series ◽  
Southeastern Brazil ◽  
Brazilian Spotted Fever

scholarly journals Spotted fever rickettsiosis in Coronel Fabriciano, Minas Gerais State

2003 ◽  
Vol 36 (4) ◽  
pp. 479-481 ◽  
Author(s):  
Márcio Antônio Moreira Galvão ◽  
Simone Berger Calic ◽  
Chequer Buffe Chamone ◽  
Cláudio Lísias Mafra S. ◽  
Gracco Cesarino Filho ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Spotted Fever ◽  
Clinical Manifestations ◽  
Minas Gerais ◽  
Spotted Fever Group ◽  
Minas Gerais State ◽  
Brazilian Spotted Fever ◽  
Spotted Fever Group Rickettsia ◽  
Rickettsial Diseases

We report cases of spotted fever rickettsiosis in Coronel Fabriciano Municipality of Minas Gerais State, Brazil. The cases occurred in May and June of 2000. During this period there were two deaths among children from an area named Pedreira in a periurban area of this municipality. In a boy who died with clinical manifestations of Brazilian spotted fever, a necropsy revealed the presence of a spotted fever group Rickettsia. The serological results confirm the difficulty in the differential diagnosis of patients with symptoms of rickettsial diseases.

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