Prospective NCCTG quality of life (QOL) study in adult newly diagnosed high-grade gliomas (HGG)

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 1524-1524
Author(s):  
P. D. Brown ◽  
K. V. Ballman ◽  
T. A. Rummans ◽  
M. J. Maurer ◽  
J. A. Sloan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
High Grade ◽  
Newly Diagnosed ◽  
High Grade Gliomas

A Prospective Study of Quality of Life in Adults With Newly Diagnosed High-Grade Gliomas

2008 ◽  
Vol 31 (2) ◽  
pp. 163-168 ◽  
Author(s):  
Paul D. Brown ◽  
Paul A. Decker ◽  
Teresa A. Rummans ◽  
Matthew M. Clark ◽  
Marlene H. Frost ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prospective Study ◽  
High Grade ◽  
Newly Diagnosed ◽  
High Grade Gliomas ◽  
A Prospective Study

Prospective NCCTG quality of life (QOL) study in adult newly diagnosed high-grade gliomas (HGG)

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 1524-1524
Author(s):  
P. D. Brown ◽  
K. V. Ballman ◽  
T. A. Rummans ◽  
M. J. Maurer ◽  
J. A. Sloan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
High Grade ◽  
Newly Diagnosed ◽  
High Grade Gliomas

A Prospective Study of Quality of Life in Adults with Newly Diagnosed High-grade Gliomas: The Impact of the Extent of Resection on Quality of Life and Survival

Neurosurgery ◽  
2005 ◽  
Vol 57 (3) ◽  
pp. 495-504 ◽  
Author(s):  
Paul D. Brown ◽  
Matthew J. Maurer ◽  
Teresa A. Rummans ◽  
Bruce E. Pollock ◽  
Karla V. Ballman ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Extent Of Resection ◽  
High Grade ◽  
Newly Diagnosed ◽  
Total Resection ◽  
Multivariable Analyses ◽  
High Grade Gliomas ◽  
Over Time

ABSTRACT OBJECTIVE: To describe the quality of life (QOL) over time for adults with newly diagnosed high-grade gliomas and to examine the relationship between QOL and outcome data collected in three prospective cooperative group clinical trials. METHODS: The QOL study was a companion protocol for three Phase II high-grade glioma protocols. Five self-administered forms were completed by patients to assess QOL at study entry, 2 months, and 4 months after enrollment. RESULTS: QOL data were available for baseline, first, and second subsequent follow-up evaluations for 89%, 71%, and 69% of patients, respectively. A significant proportion of patients (47.1%) experienced impaired QOL (QOL ≤ 50) in at least one measure at subsequent evaluations, whereas most patients (88%) with impaired QOL at baseline continued to have impaired QOL at subsequent evaluations. On multivariable analyses, baseline QOL measures were predictive of QOL at the time of follow-up. In addition, patients who underwent a gross total resection were much less likely to have impaired QOL (P = 0.006), were less likely to experience worsening depression (P = 0.0008), and were more likely to have improved QOL (P = 0.003) at their first follow-up evaluation. Changes in QOL measures over time were not found to be associated with survival in multivariable analyses that adjusted for known prognostic variables; variables that were independently associated with improved survival were better performance status (P < 0.001), younger age (P < 0.001), and greater extent of resection (P < 0.001). CONCLUSION: Baseline QOL was predictive of QOL over time. Gross total resection was associated with longer survival and improved QOL over time for patients with high-grade gliomas.

Prospective Study of Quality of Life in Adults with Newly Diagnosed High-grade Gliomas

2005 ◽  
Vol 76 (3) ◽  
pp. 283-291 ◽  
Author(s):  
Paul D. Brown ◽  
Karla V. Ballman ◽  
Teresa A. Rummans ◽  
Matthew J. Maurer ◽  
Jeff A. Sloan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prospective Study ◽  
High Grade ◽  
Newly Diagnosed ◽  
High Grade Gliomas

Coping with a newly diagnosed high-grade glioma: patient-caregiver dyad effects on quality of life

2016 ◽  
Vol 129 (1) ◽  
pp. 155-164 ◽  
Author(s):  
K. Baumstarck ◽  
T. Leroy ◽  
Z. Hamidou ◽  
E. Tabouret ◽  
P. Farina ◽  
...  
Keyword(s):  
Quality Of Life ◽  
High Grade Glioma ◽  
High Grade ◽  
Newly Diagnosed ◽  
Glioma Patient

scholarly journals Assessment of clinical and nonclinical characteristics associated with health-related quality of life in patients with high-grade gliomas: a feasibility study

2014 ◽  
Vol 22 (5) ◽  
pp. 1349-1362 ◽  
Author(s):  
Kimberly R. Porter ◽  
Usha Menon ◽  
Nicholas A. Vick ◽  
John L. Villano ◽  
Michael L. Berbaum ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Feasibility Study ◽  
High Grade ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
High Grade Gliomas

Complementary Therapy Use and Quality of Life in Persons with High-Grade Gliomas

2006 ◽  
Vol 38 (4) ◽  
pp. 212-220 ◽  
Author(s):  
Sherry Fox ◽  
Edward R. Laws ◽  
Frederick Anderson ◽  
Elana Farace
Keyword(s):  
Quality Of Life ◽  
Complementary Therapy ◽  
High Grade ◽  
High Grade Gliomas
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