Phase 1/2a study of EKB-569, an irreversible inhibitor of epidermal growth factor receptor, in combination with 5-fluorouracil, leucovorin, and oxaliplatin (FOLFOX-4) in patients with advanced colorectal cancer (CRC)

Growth Factor ◽

Epidermal Growth Factor ◽

Phase 1 ◽

Growth Factor Receptor ◽

Irreversible Inhibitor ◽

Phase 1/2a study of EKB-569, an irreversible inhibitor of epidermal growth factor receptor, in combination with 5-fluorouracil, leucovorin, and oxaliplatin (FOLFOX-4) in patients with advanced colorectal cancer (CRC)

Journal of Clinical Oncology ◽

10.1200/jco.2004.22.90140.3579 ◽

2004 ◽

Vol 22 (14_suppl) ◽

pp. 3579-3579 ◽

Cited By ~ 1

Author(s):

S. Tejpar ◽

E. Van Cutsem ◽

E. Gamelin ◽

D. Machover ◽

P. Soulie ◽

...

Keyword(s):

Colorectal Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phase 1 ◽

Growth Factor Receptor ◽

Irreversible Inhibitor ◽

To Give or Not to Give Anti–Epidermal Growth Factor Receptor (EGFR) Monoclonal Antibodies to Patients With KRAS G13D Mutation in Advanced Colorectal Cancer

Clinical Colorectal Cancer ◽

10.1016/j.clcc.2011.10.005 ◽

2012 ◽

Vol 11 (2) ◽

pp. 85-87 ◽

Cited By ~ 1

Author(s):

Richard Kim ◽

Timothy Kubal

Keyword(s):

Colorectal Cancer ◽

Monoclonal Antibodies ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Epidermal growth factor receptor (EGFR) copy number (CN) as a biomarker of prognosis and panitumumab (Pan) benefit in RAS-wt advanced colorectal cancer (aCRC)

Annals of Oncology ◽

10.1093/annonc/mdx393.071 ◽

2017 ◽

Vol 28 ◽

pp. v185 ◽

Cited By ~ 3

Author(s):

J. Seligmann ◽

H. Wood ◽

S. Richman ◽

F. Elliott ◽

M. Taylor ◽

...

Keyword(s):

Colorectal Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Copy Number ◽

Growth Factor Receptor ◽

First-line gefitinib combined with simplified FOLFOX-6 in patients with epidermal growth factor receptor-positive advanced colorectal cancer

Journal of Clinical Oncology ◽

10.1200/jco.2005.23.16_suppl.3659 ◽

2005 ◽

Vol 23 (16_suppl) ◽

pp. 3659-3659 ◽

Cited By ~ 7

Author(s):

M. G. Zampino ◽

K. Lorizzo ◽

C. Massacesi ◽

A. Rizzi ◽

S. Crispino ◽

...

Keyword(s):

Colorectal Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

First Line ◽

Epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), ZD1839 (‘Iressa’), in combination with 5-fluorouracil (5-FU) and leucovorin (LV), in advanced colorectal cancer (ACRC)

European Journal of Cancer ◽

10.1016/s0959-8049(01)80551-7 ◽

2001 ◽

Vol 37 ◽

pp. S18-S19 ◽

Cited By ~ 6

Author(s):

L. Hammond ◽

J. Figueroa ◽

L. Schwartzberg ◽

L. Ochoa ◽

M. Hidalgo ◽

...

Keyword(s):

Colorectal Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Egfr Tki

Epidermal growth factor receptor serum (sEGFR) level may predict response in patients with EGFR positive advanced colorectal cancer treated with gefitinib?

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-008-0722-x ◽

2008 ◽

Vol 63 (1) ◽

pp. 139-148 ◽

Cited By ~ 9

Author(s):

M. G. Zampino ◽

E. Magni ◽

L. Santoro ◽

L. Zorzino ◽

P. Dell’Orto ◽

...

Keyword(s):

Colorectal Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Gene Polymorphisms of Epidermal Growth Factor Receptor and its Downstream Effector, Interleukin-8, Predict Oxaliplatin Efficacy in Patients with Advanced Colorectal Cancer

Clinical Colorectal Cancer ◽

10.3816/ccc.2005.n.025 ◽

2005 ◽

Vol 5 (2) ◽

pp. 124-131 ◽

Cited By ~ 48

Author(s):

Wu Zhang ◽

Jan Stoehlmacher ◽

David J. Park ◽

Dongyun Yang ◽

Erin Borchard ◽

...

Keyword(s):

Colorectal Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Gene Polymorphisms ◽

Growth Factor Receptor ◽

Interleukin 8 ◽

Downstream Effector ◽

Somatic Profiling of the Epidermal Growth Factor Receptor Pathway in Tumors from Patients with Advanced Colorectal Cancer Treated with Chemotherapy ± Cetuximab

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-12-2581 ◽

2013 ◽

Vol 19 (15) ◽

pp. 4104-4113 ◽

Cited By ~ 59

Author(s):

Christopher G. Smith ◽

David Fisher ◽

Bart Claes ◽

Timothy S. Maughan ◽

Shelley Idziaszczyk ◽

...

Keyword(s):

Colorectal Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

EKB-569, an irreversible inhibitor of the epidermal growth factor receptor: Phase 1 trial results in patients with advanced solid tumors

European Journal of Cancer ◽

10.1016/s0959-8049(02)80854-1 ◽

2002 ◽

Vol 38 ◽

pp. S64

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Solid Tumors ◽

Phase 1 ◽

Growth Factor Receptor ◽

Advanced Solid Tumors ◽

Irreversible Inhibitor ◽

Epidermal Growth ◽

Receptor Phase

The human epidermal growth factor receptor (EGFR) gene in European patients with advanced colorectal cancer harbors infrequent mutations in its tyrosine kinase domain

BMC Medical Genetics ◽

10.1186/1471-2350-12-144 ◽

2011 ◽

Vol 12 (1) ◽

Cited By ~ 28

Author(s):

Brigitte Metzger ◽

Laetitia Chambeau ◽

Dominique Y Begon ◽

Carlo Faber ◽

Jacques Kayser ◽

...

Keyword(s):

Colorectal Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Kinase Domain ◽

Tyrosine Kinase Domain ◽

Egfr Gene ◽