The human epidermal growth factor receptor (EGFR) gene in European patients with advanced colorectal cancer harbors infrequent mutations in its tyrosine kinase domain

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Kinase Domain ◽

Tyrosine Kinase Domain ◽

Egfr Gene ◽

3054 POSTER Comparison of paired patient primary and liver metastatic colorectal cancer (CRC) tissues for epidermal growth factor receptor (EGFR) protein expression and the presence of mutations in the EGFR tyrosine kinase domain

European Journal of Cancer Supplements ◽

10.1016/s1359-6349(07)70982-5 ◽

2007 ◽

Vol 5 (4) ◽

pp. 252

Author(s):

J.A. Maroun ◽

D.J. Jonker ◽

H.C. Birnboim ◽

T. Moyana ◽

D. Wang ◽

...

Keyword(s):

Colorectal Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Protein Expression ◽

Metastatic Colorectal Cancer ◽

Growth Factor Receptor ◽

Kinase Domain ◽

Tyrosine Kinase Domain ◽

To Give or Not to Give Anti–Epidermal Growth Factor Receptor (EGFR) Monoclonal Antibodies to Patients With KRAS G13D Mutation in Advanced Colorectal Cancer

Clinical Colorectal Cancer ◽

10.1016/j.clcc.2011.10.005 ◽

2012 ◽

Vol 11 (2) ◽

pp. 85-87 ◽

Cited By ~ 1

Author(s):

Richard Kim ◽

Timothy Kubal

Keyword(s):

Colorectal Cancer ◽

Monoclonal Antibodies ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Evoidence that the Tyrosine Kinase Domain of a Small Fraction of Epidermal Growth Factor Receptor Molecules is Exposed on the Outer Surface of A431 Cells.

Cell Structure and Function ◽

10.1247/csf.16.217 ◽

1991 ◽

Vol 16 (3) ◽

pp. 217-223 ◽

Cited By ~ 3

Author(s):

Seiji Ihara ◽

Fumiko Maeda-Takekoshi ◽

Masataka Takekoshi ◽

Minehiko Yokoyama ◽

Sadatoshi Sakuma ◽

...

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Outer Surface ◽

Growth Factor Receptor ◽

Kinase Domain ◽

Tyrosine Kinase Domain ◽

A431 Cells ◽

Epidermal growth factor receptor (EGFR) copy number (CN) as a biomarker of prognosis and panitumumab (Pan) benefit in RAS-wt advanced colorectal cancer (aCRC)

Annals of Oncology ◽

10.1093/annonc/mdx393.071 ◽

2017 ◽

Vol 28 ◽

pp. v185 ◽

Cited By ~ 3

Author(s):

J. Seligmann ◽

H. Wood ◽

S. Richman ◽

F. Elliott ◽

M. Taylor ◽

...

Keyword(s):

Colorectal Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Copy Number ◽

Growth Factor Receptor ◽

Phase 1/2a study of EKB-569, an irreversible inhibitor of epidermal growth factor receptor, in combination with 5-fluorouracil, leucovorin, and oxaliplatin (FOLFOX-4) in patients with advanced colorectal cancer (CRC)

Journal of Clinical Oncology ◽

10.1200/jco.2004.22.14_suppl.3579 ◽

2004 ◽

Vol 22 (14_suppl) ◽

pp. 3579-3579 ◽

Cited By ~ 11

Author(s):

S. Tejpar ◽

E. Van Cutsem ◽

E. Gamelin ◽

D. Machover ◽

P. Soulie ◽

...

Keyword(s):

Colorectal Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phase 1 ◽

Growth Factor Receptor ◽

Irreversible Inhibitor ◽

Phase 1/2a study of EKB-569, an irreversible inhibitor of epidermal growth factor receptor, in combination with 5-fluorouracil, leucovorin, and oxaliplatin (FOLFOX-4) in patients with advanced colorectal cancer (CRC)

Journal of Clinical Oncology ◽

10.1200/jco.2004.22.90140.3579 ◽

2004 ◽

Vol 22 (14_suppl) ◽

pp. 3579-3579 ◽

Cited By ~ 1

Author(s):

S. Tejpar ◽

E. Van Cutsem ◽

E. Gamelin ◽

D. Machover ◽

P. Soulie ◽

...

Keyword(s):

Colorectal Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phase 1 ◽

Growth Factor Receptor ◽

Irreversible Inhibitor ◽

Clinico-Pathological and Biological Significance of Tyrosine Kinase Domain Gene Mutations and Overexpression of Epidermal Growth Factor Receptor for Lung Adenocarcinoma

Journal of Thoracic Oncology ◽

10.1016/s1556-0864(15)30407-x ◽

2006 ◽

Vol 1 (8) ◽

pp. 787-795 ◽

Cited By ~ 7

Author(s):

Kouki Ohtsuka ◽

Hiroaki Ohnishi ◽

Go Furuyashiki ◽

Hiroshi Nogami ◽

Yoshihiko Koshiishi ◽

...

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Lung Adenocarcinoma ◽

Biological Significance ◽

Growth Factor Receptor ◽

Gene Mutations ◽

Kinase Domain ◽

Tyrosine Kinase Domain ◽

Epidermal growth factor receptor (EGFR) gene promoter methylation and cetuximab treatment in colorectal cancer patients

British Journal of Cancer ◽

10.1038/bjc.2011.161 ◽

2011 ◽

Vol 104 (11) ◽

pp. 1786-1790 ◽

Cited By ~ 48

Author(s):

M Scartozzi ◽

I Bearzi ◽

A Mandolesi ◽

R Giampieri ◽

L Faloppi ◽

...

Keyword(s):

Colorectal Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Cancer Patients ◽

Growth Factor Receptor ◽

Gene Promoter ◽

Egfr Gene ◽

Epidermal Growth ◽

Colorectal Cancer Patients

Clinico-Pathological and Biological Significance of Tyrosine Kinase Domain Gene Mutations and Overexpression of Epidermal Growth Factor Receptor for Lung Adenocarcinoma

Journal of Thoracic Oncology ◽

10.1097/01243894-200610000-00006 ◽

2006 ◽

Vol 1 (8) ◽

pp. 787-795 ◽

Cited By ~ 21

Author(s):

Kouki Ohtsuka ◽

Hiroaki Ohnishi ◽

Go Furuyashiki ◽

Hiroshi Nogami ◽

Yoshihiko Koshiishi ◽

...

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Lung Adenocarcinoma ◽

Biological Significance ◽

Growth Factor Receptor ◽

Gene Mutations ◽

Kinase Domain ◽

Tyrosine Kinase Domain ◽

Potential tripeptides against the tyrosine kinase domain of human epidermal growth factor receptor (HER) 2 through computational and kinase assay approaches

Journal of Molecular Graphics and Modelling ◽

10.1016/j.jmgm.2020.107564 ◽

2020 ◽

Vol 97 ◽

pp. 107564

Author(s):

Supaphorn Seetaha ◽

Bundit Boonyarit ◽

Sissades Tongsima ◽

Napat Songtawee ◽

Kiattawee Choowongkomon

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Growth Factor Receptor ◽

Kinase Domain ◽

Kinase Assay ◽

Tyrosine Kinase Domain ◽

Her 2 ◽