Practice implications of the high false negative rate of sentinel lymph node biopsy reported in NSABP-32

2005 ◽  
Vol 23 (16_suppl) ◽  
pp. 812-812 ◽  
Author(s):  
L. Esserman ◽  
K. Sepucha
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
False Negative ◽  
False Negative Rate ◽  
Lymph Node Biopsy ◽  
Node Biopsy ◽  
Negative Rate ◽  
High False Negative Rate

scholarly journals 489 The Role of Sentinel Lymph Node Biopsy in Cutaneous Head and Neck Melanoma: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
E Johnston ◽  
S Taylor ◽  
F Bannon ◽  
S McAllister
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Head And Neck ◽  
False Negative ◽  
False Negative Rate ◽  
Lymph Node Biopsy ◽  
Node Biopsy ◽  
Negative Rate ◽  
Sentinel Node Identification

Abstract Introduction and Aims The aim of this systematic review is to provide an up-to-date evaluation of the role and test performance of sentinel lymph node biopsy (SLNB) in the head and neck. Method This review follows the PRISMA guidelines. Database searches for MEDLINE and EMBASE were constructed to retrieve human studies published between 1st January 2010 and 1st July 2020 assessing the role and accuracy of sentinel lymph node biopsy in cutaneous malignant melanoma of the head and neck. Articles were independently screened by two reviewers and critically appraised using the MINORS criteria. The primary outcomes consisted of the sentinel node identification rate and test-performance measures, including the false-negative rate and the posttest probability negative. Results A total of 27 studies, including 4688 patients, met the eligibility criteria. Statistical analysis produced weighted summary estimates for the sentinel node identification rate of 97.3% (95% CI, 95.9% to 98.6%), the false-negative rate of 21.3% (95% CI, 17.0% to 25.4%) and the posttest probability negative of 4.8% (95% CI, 3.9% to 5.8%). Discussion Sentinel lymph node biopsy is accurate and feasible in the head and neck. Despite technical improvements in localisation techniques, the false negative rate remains disproportionately higher than for melanoma in other anatomical sites.

scholarly journals False Negative Rate of Sentinel Lymph Node Biopsy in Multicentric and Multifocal Breast Cancers May be Higher in Cases with Large Additive Tumor Burden

2009 ◽  
Vol 15 (6) ◽  
pp. 645-648 ◽  
Author(s):  
Regina M. Fearmonti ◽  
Larissa I. Batista ◽  
Funda Meric-Bernstam ◽  
Isabelle Bedrosian ◽  
Henry M. Kuerer ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
False Negative ◽  
False Negative Rate ◽  
Lymph Node Biopsy ◽  
Tumor Burden ◽  
Breast Cancers ◽  
Node Biopsy ◽  
Negative Rate

Correlation Between Clinical Nodal Status and Sentinel Lymph Node Biopsy False Negative Rate After Neoadjuvant Chemotherapy

2012 ◽  
Vol 36 (12) ◽  
pp. 2847-2852 ◽  
Author(s):  
Maiko Takahashi ◽  
Hiromitsu Jinno ◽  
Tetsu Hayashida ◽  
Michio Sakata ◽  
Keiko Asakura ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Neoadjuvant Chemotherapy ◽  
False Negative ◽  
False Negative Rate ◽  
Lymph Node Biopsy ◽  
Nodal Status ◽  
Node Biopsy ◽  
Negative Rate

Determining the False-Negative Rate Using Fluorescence Image–Assisted Sentinel Lymph Node Biopsy in Cutaneous Melanoma

2018 ◽  
Vol 80 (1) ◽  
pp. 54-58 ◽  
Author(s):  
Rafael A. Couto ◽  
Gregory A. Lamaris ◽  
Rebecca Knackstedt ◽  
Brendan Alleyne ◽  
Paul Durand ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Cutaneous Melanoma ◽  
False Negative ◽  
False Negative Rate ◽  
Lymph Node Biopsy ◽  
Fluorescence Image ◽  
Node Biopsy ◽  
Negative Rate
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