Long-term quality of life comparison after endoscopic submucosal dissection versus surgery in early gastric cancer patients.

2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 24-24
Author(s):  
Young-Il Kim ◽  
Young Ae Kim ◽  
Chan Gyoo Kim ◽  
Keun Won Ryu ◽  
Young Woo Kim ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gastric Cancer ◽  
Early Gastric Cancer ◽  
Endoscopic Submucosal Dissection ◽  
Cancer Patients ◽  
Eortc Qlq ◽  
Gastric Cancer Patients

24 Background: The aim of this study was to compare the serial changes of health-related quality of life (HRQOL) after Endoscopic submucosal dissection (ESD) with those after surgery in patients with early gastric cancer (EGC). Methods: Gastric cancer patients were prospectively enrolled from 2004 through 2007. HRQOLs of 161 EGC patients were prospectively assessed by European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC-QLQ-C30) and the stomach cancer-specific module EORTC-QLQ-STO22 at the baseline, 1, 6, 12, 18 and 24 months after treatments. Analysis was done using the generalized linear model and paired- ttests. Results: Of 161 patients, 48 (29.8%) underwent ESD (ESD group) and 113 (70.2%) underwent surgery (surgery group). The median age of stomach cancer patients was 57 years. Surgery group had poorer scores compared with those of ESD group in the most HRQOL factors one month after treatments ( P< 0.05), except for emotional and cognitive functioning, financial problems, anxiety, and hair loss. However, most of the functional and symptom scales after surgery subsequently improved and became insignificant until 24 months of follow up. Only 3 parameters including physical functioning, diarrhea and body image in ESD group still remained better until 24 months after treatment ( P< 0.05). Conclusions: Because poorer HRQOLs after surgery in the early post-treatment periods become insignificant during long-term follow-up, surgical treatment should not be discouraged in EGC treatment solely based on the QOL aspects.

Predicting the Quality of Life in Patients with Gastrointestinal Cancers in Iranian Population

2016 ◽  
Vol 9 (1) ◽  
pp. 43
Author(s):  
Aliakbar Hajaghamohammadi ◽  
Somayeh Ahmadi Gooraji ◽  
Ali Zargar
Keyword(s):  
Quality Of Life ◽  
Gastric Cancer ◽  
Cancer Patients ◽  
Study Data ◽  
Cross Sectional ◽  
Social And Emotional ◽  
Gi Cancers ◽  
Eortc Qlq ◽  
Gastric Cancer Patients

BACKGROUND: Evaluation of the quality of life (QoL) of cancer patients gives valuable information regarding the burden of disease, type of treatment and its side effects in studies on chronic diseases. In this study an attempt is made to predict the QoL of patients with gastrointestinal (GI) cancer.METHODS: In a cross sectional prospective study, data of 107 patients with GI cancers 58 male & 49 female with a mean age of 60.7±10.5 referred to a hospital from April 2009 to June 2015 were collected by using two standard questionnaires of EORTC-QLQ C30 and EORTC-QLQ-GINET 21. Data analysis was done using multivariate analysis of variance (MANOVA) and correlation test in soft wares of STATA and SPSS.16.RESULTS: Total QoL score was 50.7±24.6 in patients with gastrointestinal cancer which is almost optimal. Symptoms level was more in gastric cancer patients and their major complaints were constipation and diarrhea.  QoL of patients with GI cancers were more affected by the educational level and type of cancer (P<0.05).A high correlation of QoL was related to social and emotional domains (P<0.05). Mean score of QoL was more in males with colorectal cancer, educated and retired patients (P<0.05).CONCLUSION: the social and emotional support to patients with esophageal cancer and to reduce the level of symptoms in patients with gastric cancer due to complications of their diseases or treatment should be of consideration to improve their QoL.

Long-term quality of life and nutritional results after laparoscopic sentinel node navigation surgery versus laparoscopic standard gastrectomy for early gastric cancer: Secondary outcomes of a multicenter, randomized phase 3 trial (SENORITA).

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 4054-4054
Author(s):  
Bang Wool Eom ◽  
Hong Man Yoon ◽  
Young-Woo Kim ◽  
Jae Seok Min ◽  
Ji Yeong An ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gastric Cancer ◽  
Early Gastric Cancer ◽  
Phase 3 ◽  
Navigation Surgery ◽  
Sentinel Node Navigation Surgery ◽  
Eortc Qlq C30 ◽  
Eortc Qlq

4054 Background: Laparoscopic sentinel node navigation surgery (LSNNS) has been suggested as an alternative to laparoscopic standard gastrectomy (LSG) in early gastric cancer patients to improve long-term quality of life (QOL) and nutritional outcomes. Here, we present 3-year results of patient-reported quality of life (QOL) and nutrition, secondary endpoints of SENORITA trial. Methods: SENORITA is a prospective multicenter randomized phase 3 trial. Patients diagnosed with early gastric cancer of 3 cm or less were randomly allocated (1:1) to LSNNS for stomach preservation or LSG. The primary endpoint was 3-year disease-free survival. In this study, we analyzed QOL assessed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) and EORTC stomach module (STO22) and nutritional parameters at 3, 12, 24, and 36 months after surgery. Linear mixed model analyses was used to evaluate differences between the two groups. This trial is registered with ClinicalTrials.gov, NCT01804998. Results: From March 2013 to March 2017, a total of 580 patients were randomly assigned and 527 patients were included in the modified intention-to-treat analysis population (258 in LSNNS and 269 in LSG group). QOL questionnaires were available for 99.4% of patients at baseline and then for 92.2%, 83.2%, 72.8%, and 66.9% at 3, 12, 24, and 36 months after surgery, respectively. The LSNNS group had higher physical function score than the LSG group at all time points (p = 0.002). However, there were no significant differences in other scales of EORTC QLQ-C30. Regarding EORTC QLQ-STO22, pain, eating restriction, anxiety, and taste scores were lower (better QOL) at all time points in the LSNNS group than in the LSG group (p = 0.002, < 0.001, < 0.001, and < 0.001, respectively). The summary score of EORTC QLQ-STO22 was also higher in the LSNNS group representing better QOL (p < 0.001). Body mass index, hemoglobin and total protein were significantly higher in the LSNNS group compared with the LSG group. Conclusions: The LSNNS group had better physical function and less symptoms, including pain, eating restriction, anxiety, and taste change compared with the LSG group. Moreover, the nutritional parameters were better maintained in the LSNNS group than in the LSG group. These findings showed benefits of stomach preserving surgery in LSNNS and can be used to help decision making about treatment for patients with early gastric cancer. Clinical trial information: NCT01804998.

scholarly journals Psychosocial Aspects and Quality of Life in Cancer Patients undergoing Surgery

2021 ◽  
Vol 12 (4) ◽  
pp. 78-84
Author(s):  
M. Bakos ◽  
T. Jankovic ◽  
M. Vidiscak ◽  
S. Durdik
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Negative Impact ◽  
European Organization ◽  
Term Survival ◽  
Physical Relationship ◽  
End Of Treatment ◽  
Eortc Qlq

Introduction:Quality of life in cancer patients and probably also long term survival is negatively affected with fear of the recurrence of cancer and consequences of aggressive therapy. This is the reason for anxiety, depressions, and frustration which are accompanied by cognitive, emotional and behavioral disorders in their physical, relationship, sexual and social func- tioning. The aim of our study is to analyze the dynamics of evolution of the psychosocial loads and qualitative changes its symptomatology in cancer patients who survival 1-4 years after surgery. Material and methods:For assessment of psychosocial mor- bidity ́s in measure in surgery patients standardized question- naires of European Organization for Research and Treatment of Cancer- questionnaire EORTC QLQ-C30.3 (Quality of Life- C.30.3) and its module EORTC QLQ- BR23 were used. Results:The degree of psychosocial mortality in survival pa- tients one year after MRM in our group clearly demonstrated that these patients suffered because of consequences of psy- chosocial loads. It results from fear of recurrence of cancer and next functional, emotional, cognitive and social disorders with- out regard for surgery range. The degree of psychosocial loads in patients after MRM is still more than 4 years after end of treatment. Results show, that after the end of treatment there are many changes in their lives - anxiety and depressions can lead to psychical lability because of higher doubts, nervous- ness, irritability, helplessness and loneliness in their sufferers. Conclusion:Out-patient psychosocial interventions and pre- ventions because of negative impact of ongoing and changing psychosocial loads becomes necessary. It means that there is negative impact on quality of life; of long term cancer remis- sion and survival of patients after surgery.

scholarly journals Long Term Survival and Quality of Life after Minimally Invasive Surgery for Early Gastric Cancer.

1998 ◽  
Vol 31 (4) ◽  
pp. 1015-1019
Author(s):  
Tetsuro Kubota ◽  
Yoichiro Ishikawa ◽  
Soichiro Isshiki ◽  
Takeyoshi Yokoyama ◽  
Koji Fujita ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gastric Cancer ◽  
Minimally Invasive Surgery ◽  
Early Gastric Cancer ◽  
Minimally Invasive ◽  
Invasive Surgery ◽  
Term Survival ◽  
Long Term Survival
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