Predicting the Quality of Life in Patients with Gastrointestinal Cancers in Iranian Population

2016 ◽  
Vol 9 (1) ◽  
pp. 43
Author(s):  
Aliakbar Hajaghamohammadi ◽  
Somayeh Ahmadi Gooraji ◽  
Ali Zargar

BACKGROUND: Evaluation of the quality of life (QoL) of cancer patients gives valuable information regarding the burden of disease, type of treatment and its side effects in studies on chronic diseases. In this study an attempt is made to predict the QoL of patients with gastrointestinal (GI) cancer.METHODS: In a cross sectional prospective study, data of 107 patients with GI cancers 58 male & 49 female with a mean age of 60.7±10.5 referred to a hospital from April 2009 to June 2015 were collected by using two standard questionnaires of EORTC-QLQ C30 and EORTC-QLQ-GINET 21. Data analysis was done using multivariate analysis of variance (MANOVA) and correlation test in soft wares of STATA and SPSS.16.RESULTS: Total QoL score was 50.7±24.6 in patients with gastrointestinal cancer which is almost optimal. Symptoms level was more in gastric cancer patients and their major complaints were constipation and diarrhea.  QoL of patients with GI cancers were more affected by the educational level and type of cancer (P<0.05).A high correlation of QoL was related to social and emotional domains (P<0.05). Mean score of QoL was more in males with colorectal cancer, educated and retired patients (P<0.05).CONCLUSION: the social and emotional support to patients with esophageal cancer and to reduce the level of symptoms in patients with gastric cancer due to complications of their diseases or treatment should be of consideration to improve their QoL.

2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 24-24
Author(s):  
Young-Il Kim ◽  
Young Ae Kim ◽  
Chan Gyoo Kim ◽  
Keun Won Ryu ◽  
Young Woo Kim ◽  
...  

24 Background: The aim of this study was to compare the serial changes of health-related quality of life (HRQOL) after Endoscopic submucosal dissection (ESD) with those after surgery in patients with early gastric cancer (EGC). Methods: Gastric cancer patients were prospectively enrolled from 2004 through 2007. HRQOLs of 161 EGC patients were prospectively assessed by European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC-QLQ-C30) and the stomach cancer-specific module EORTC-QLQ-STO22 at the baseline, 1, 6, 12, 18 and 24 months after treatments. Analysis was done using the generalized linear model and paired- ttests. Results: Of 161 patients, 48 (29.8%) underwent ESD (ESD group) and 113 (70.2%) underwent surgery (surgery group). The median age of stomach cancer patients was 57 years. Surgery group had poorer scores compared with those of ESD group in the most HRQOL factors one month after treatments ( P< 0.05), except for emotional and cognitive functioning, financial problems, anxiety, and hair loss. However, most of the functional and symptom scales after surgery subsequently improved and became insignificant until 24 months of follow up. Only 3 parameters including physical functioning, diarrhea and body image in ESD group still remained better until 24 months after treatment ( P< 0.05). Conclusions: Because poorer HRQOLs after surgery in the early post-treatment periods become insignificant during long-term follow-up, surgical treatment should not be discouraged in EGC treatment solely based on the QOL aspects.


2020 ◽  
Vol 31 ◽  
pp. S1057-S1058
Author(s):  
H-B. Zhang ◽  
Y-J. Zhu ◽  
J.J. Mao ◽  
J-J. Peng ◽  
X-S. Chang ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Dzung Ngoc Thi Dang ◽  
Lan Ngoc Thi Nguyen ◽  
Nga Thi Dang ◽  
Huy Quang Dang ◽  
Thanh Van Ta

Background. Gastric cancer (GC) is one of the leading causes of cancer-related death in Vietnam. Research on health-related quality of life of Vietnamese gastric cancer patients is still in its infancy. Aim. To assess the health-related quality of life (HRQOL) of GC patients using the 15D instrument. Materials and Method. 182 Vietnamese gastric cancer patients were selected to be interviewed and their HRQOL was assessed using the generic 15D questionnaire. Tables regarding history, disease characteristics, and HRQOL of participants were formulated according to genders using STATA 12.0. Results. The average age of the participants was 60.8 ± 11.6. The average time from diagnosis to the date of interview was 14.8 ± 8.4 months. The health-related quality of life (HRQOL) index score of gastric cancer patients using the 15D instrument was 0.92 ± 0.08, in which the “sexual activity” dimension had the lowest score of 0.66. Also, our study found several factors affecting HRQOL, including age, occupation, education, disease stage, treatment, and time from the date of diagnosis. Conclusion. The 15D instrument was a suitable tool to assess Vietnamese gastric cancer patients’ quality of life. Findings from the study suggest the importance of frequently measuring personal functioning and performance of GC patients as parts of QOL assessment during clinical examination. It also implies the needs for more focused policies on raising the overall quality of life of patients such as encouragement of periodical HQROL assessment and acknowledging HRQOL as a treatment/intervention goal besides the 5-year survival rate.


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