Progress and Road Blocks in the Development of Carbon Nanotubes as Cellular Carriers for Nucleic Acids

2011 ◽  
pp. 723-748
Author(s):  
Bridget D. Dolash ◽  
Donald E. Bergstrom
Keyword(s):  
Carbon Nanotubes ◽  
Nucleic Acids

scholarly journals Hybrids of Nucleic Acids and Carbon Nanotubes for Nanobiotechnology

Nanomaterials ◽  
2015 ◽  
Vol 5 (1) ◽  
pp. 321-350 ◽  
Author(s):  
Kazuo Umemura
Keyword(s):  
Carbon Nanotubes ◽  
Nucleic Acids

scholarly journals Interaction of nucleic acids with carbon nanotubes and dendrimers

2012 ◽  
Vol 37 (3) ◽  
pp. 457-474 ◽  
Author(s):  
Bidisha Nandy ◽  
Mogurampelly Santosh ◽  
Prabal K Maiti
Keyword(s):  
Carbon Nanotubes ◽  
Nucleic Acids

Novel Multifunctional Hybrids of Single-Walled Carbon Nanotubes with Nucleic Acids: Synthesis and Interactions with Living Cells

2014 ◽  
Vol 6 (3) ◽  
pp. 1454-1461 ◽  
Author(s):  
Evgeny K. Apartsin ◽  
Marina Yu. Buyanova ◽  
Darya S. Novopashina ◽  
Elena I. Ryabchikova ◽  
Anton V. Filatov ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Nucleic Acids ◽  
Single Walled Carbon Nanotubes ◽  
Living Cells ◽  
Single Walled Carbon ◽  
Walled Carbon Nanotubes

scholarly journals Cover Feature: Carbon Nanotubes Decorated with Cationic Carbosilane Dendrons and Their Hybrids with Nucleic Acids (ChemNanoMat 2/2018)

ChemNanoMat ◽  
2018 ◽  
Vol 4 (2) ◽  
pp. 150-150
Author(s):  
Carlos E. Gutierrez-Ulloa ◽  
Marina Yu. Buyanova ◽  
Evgeny K. Apartsin ◽  
Alya G. Venyaminova ◽  
Fco. Javier de la Mata ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Nucleic Acids

scholarly journals Extraction of Viral Nucleic Acids with Carbon Nanotubes Increases SARS-CoV-2 RT-qPCR Detection Sensitivity

2021 ◽  
Author(s):  
Sanghwa Jeong ◽  
Eduardo G. Grandio ◽  
Nicole Navarro ◽  
Rebecca L. Pinals ◽  
Francis Ledesma ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Nucleic Acids ◽  
Rna Extraction ◽  
High Sensitivity ◽  
Human Saliva ◽  
Extraction Yield ◽  
Detection Sensitivity ◽  
High Yield ◽  
Acid Extraction ◽  
Chemical Reagents

AbstractThe global SARS-CoV-2 coronavirus pandemic has led to a surging demand for rapid and efficient viral infection diagnostic tests, generating a supply shortage in diagnostic test consumables including nucleic acid extraction kits. Here, we develop a modular method for high-yield extraction of viral single-stranded nucleic acids by using ‘capture’ ssDNA sequences attached to carbon nanotubes. Target SARS-CoV-2 viral RNA can be captured by ssDNA-nanotube constructs via hybridization and separated from the liquid phase in a single-tube system with minimal chemical reagents, for downstream quantitative reverse transcription polymerase chain reaction (RT-qPCR) detection. This nanotube-based extraction method enables 100% extraction yield of target SARS-CoV-2 RNA from phosphate buffered saline in comparison to ∼20% extraction yield when instead using a commercial silica-column kit. Notably, carbon nanotubes enable extraction of nucleic acids directly from 50% human saliva, bypassing the need for further biofluid purification and avoiding the use of DNA/RNA extraction kits. Carbon nanotube-based extraction of viral nucleic acids facilitates high-yield and high-sensitivity identification of viral nucleic acids such as the SARS-CoV-2 viral genome with reduced reliance on reagents affected by supply chain obstacles.Abstract Figure

Encoding Carbon Nanotubes with Tubular Nucleic Acids for Information Storage

2019 ◽  
Vol 141 (44) ◽  
pp. 17861-17866 ◽  
Author(s):  
Yueyue Zhang ◽  
Fan Li ◽  
Min Li ◽  
Xiuhai Mao ◽  
Xinxin Jing ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Nucleic Acids ◽  
Information Storage

Target-induced molecular-switch on triple-helix DNA-functionalized carbon nanotubes for simultaneous visual detection of nucleic acids and proteins

2020 ◽  
Vol 56 (88) ◽  
pp. 13657-13660
Author(s):  
Yan Huang ◽  
Zhihao Cheng ◽  
Rong Han ◽  
Xuan Gao ◽  
Lisheng Qian ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Carbon Nanotube ◽  
Nucleic Acids ◽  
Triple Helix ◽  
Visual Detection ◽  
Molecular Switch ◽  
Structure Change ◽  
Dna Probes ◽  
Functionalized Carbon Nanotubes

The structure change of triple-helix DNA leads the signal DNA probes changing from the protected status to the exposure status on the carbon nanotube surface, which are detected by a strip biosensor to give visible black bands.

Carbon Nanotubes Decorated with Cationic Carbosilane Dendrons and Their Hybrids with Nucleic Acids

ChemNanoMat ◽  
2017 ◽  
Vol 4 (2) ◽  
pp. 220-230 ◽  
Author(s):  
Carlos E. Gutierrez-Ulloa ◽  
Marina Yu. Buyanova ◽  
Evgeny K. Apartsin ◽  
Alya G. Venyaminova ◽  
Fco. Javier de la Mata ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Nucleic Acids
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