Thyroid emergencies: Myxedema coma and thyroid storm

Author(s):  
Dushyanthy Arasaratnam ◽  
Nadia Barghouthi ◽  
Jessica Perini ◽  
Robert Weingold
Keyword(s):  
2018 ◽  
Vol 143 (06) ◽  
pp. 397-405 ◽  
Author(s):  
Malte Milkau ◽  
Friedhelm Sayk

AbstractThyroid storm and myxedema coma are the most severe clinical forms of thyroid dysfunction. While both hyper- and hypothyroidsm are common diseases, thyroid storm and myxedema coma are rare. Due to their unspecific signs and symptoms they are often difficult to diagnose. Both disorders are medical emergencies, which still show a significant mortality. The following article summarizes diagnostic tools and treatment options for these disorders


2016 ◽  
pp. 449-449
Author(s):  
Harn-Shen Chen ◽  
Hong-Da Lin ◽  
Chen-Hsen Lee
Keyword(s):  

1992 ◽  
Vol 3 (2) ◽  
pp. 300-308 ◽  
Author(s):  
Loretta Spittle

An overview of normal thyroid function is presented to facilitate the understanding of the pathophysiology of two life-threatening thyroid disorders: thyroid storm and myxedema coma. Signs and symptoms, medical management, nursing diagnoses and interventions, and expected patient outcomes are discussed, as is the important role of the nurse as an integral member of the management team


2018 ◽  
Author(s):  
Jill Yaung

Critically ill patients may have preexisting endocrine disorders that need to be recognized and addressed. Disruption of normal endocrine gland function leads to inappropriate hormone secretion, resulting in hormone excess or deficiency. Both extremes may have detrimental systemic consequences and may pose significant challenges to the intensivist. Proper recognition of endocrine emergencies such as severe hyponatremia secondary to the syndrome of inappropriate antidiuretic hormone secretion, thyroid storm, and myxedema coma is vital, as delay in treatment may result in significant morbidity or death. This review provides an overview of common pituitary, thyroid, and parathyroid disorders and emergencies, including definitions, manifestations, diagnosis, and management. This review contains 2 figures, 5 tables, and 28 references. Key Words: acromegaly, diabetes insipidus, hyperparathyroidism, hypoparathyroidism, myxedema coma, nonthyroidal illness syndrome, syndrome of inappropriate antidiuretic hormone secretion, thyrotoxicosis, thyroid storm


2013 ◽  
Vol 24 (3) ◽  
pp. 325-332
Author(s):  
Jessica Hampton

Although thyroid dysfunction will develop in more than 12% of the US population during their lifetimes, true thyroid emergencies are rare. Thyroid storm and myxedema coma are endocrine emergencies resulting from thyroid hormone dysregulation, usually coupled with an acute illness as a precipitant. Careful assessment of risk and rapid action, once danger is identified, are essential for limiting morbidity and mortality related to thyroid storm and myxedema coma. This article reviews which patients are at risk, explains thyroid storm and myxedema coma, and describes pharmacological treatment and supportive cares.


Author(s):  
John E. Moss

Thyroid disorders are relatively uncommon among patients in the intensive care unit (ICU) but may lead to serious morbidity and death. A working knowledge of these disorders is essential to their recognition and treatment, and an intensivist should be able to recognize and treat the 3 most common thyroid disorders in the ICU: myxedema coma, thyroid storm, and euthyroid sick syndrome.


2018 ◽  
Author(s):  
Jason J Lewis ◽  
Richard E Wolfe

Acute emergent presentations of the thyroid and parathyroids are rarer occurrences in the emergency department but essential to diagnose and treat early in the course of illness. Disorders of the parathyroids are typically related to circulating calcium levels and the metabolic effects thereof, whereas thyroid deficiency or excess can lead to profound shock, coma, hypothermia, hyperthermia, and death. The diagnosis of parathyroid disease should be considered in patients presenting with signs and symptoms consistent with hyper- or hypocalcemia. Myxedema coma should be considered in any patient presenting with evidence of severe sepsis or shock, particularly when there is a history of hypothyroidism. Thyroid storm should be suspected in any patient with unexplained increased adrenergic activity, hyperpyrexia, or multiorgan failure. Empirical treatment must begin prior to definitive diagnosis in all cases. This review demonstrates how to recognize and manage acute presentations of hypo- and hyperparathyroidism, myxedema coma, and thyroid storm in the emergency setting. Patients with nondiabetic endocrine emergencies may present in extremis, and immediate stabilization, typically without confirmatory testing, is necessary. Early intervention is key in treating such presentations. This review contains 3 figures, 8 tables and 28 references Key words: disorders of the parathyroids, hyperparathyroidism, hypoparathyroidism, hypothyroidism, myxedema coma, thyroid storm, thyrotoxicosis


1985 ◽  
Vol 69 (5) ◽  
pp. 1005-1017 ◽  
Author(s):  
John T. Nicoloff
Keyword(s):  

Author(s):  
Ruchir Gupta

In this chapter the essential aspects of anesthesia for thyroid surgery are reviewed. An emphasis is placed on airway management of the thyroid patient as well as on drug therapy prior to anesthetizing thyroid patients. Myxedema coma and thyroid storm are reviewed in detail. The patient discussed is to undergo resection of a goiter. The chapter is divided into preoperative, intraoperative, and postoperative sections with important subtopics related to the main topic in each section. Preoperative topics discussed are patient hemodynamics, use of beta blockers, airway assessment, and antithyroid therapy, including iodine. Intraoperative issues covered include monitoring, awake fiber-optic intubation, and management of bleeding. Postoperative issues addressed include extubation and treatment of postoperative stridor.


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