An Introduction to Neutron Diffusion Theory and Fick’s Law of Diffusion

Author(s):  
Robert E. Masterson
2015 ◽  
Vol 39 (3) ◽  
pp. 192-197 ◽  
Author(s):  
Larissa Zhou ◽  
Kendra Nyberg ◽  
Amy C. Rowat

Diffusion is critical to physiological processes ranging from gas exchange across alveoli to transport within individual cells. In the classroom, however, it can be challenging to convey the concept of diffusion on the microscopic scale. In this article, we present a series of three exercises that use food and cooking to illustrate diffusion theory and Fick's first law. These exercises are part of a 10-wk undergraduate course that uses food and cooking to teach fundamental concepts in physiology and biophysics to students, including nonscience majors. Consistent demonstration of practical applications in a classroom setting has the potential to fundamentally change how students view the role of science in their lives (15).


1987 ◽  
Vol 252 (6) ◽  
pp. C583-C587 ◽  
Author(s):  
A. Clark ◽  
P. A. Clark ◽  
R. J. Connett ◽  
T. E. Gayeski ◽  
C. R. Honig

The subject of this brief review is the size of the local drops in PO2 around consuming mitochondria. We show that large drops (several Torr or more) are in conflict with the predictions of basic diffusion theory, when one uses accepted values for relevant parameters. In particular, oxygen diffusion coefficients must be reduced by at least a factor of 10 below measured values to reconcile Fick's law with large PO2 drops. Experimental evidence offered for large drops is often ambiguous because of system heterogeneities. In those cases where tractable models of heterogeneous systems can be developed, the experimental data are consistent with drops in PO2 on the order of a few hundredths of a Torr between cytosol and mitochondrion.


1977 ◽  
Vol 17 (1) ◽  
pp. 37-52 ◽  
Author(s):  
D. C. J. Horncastle

Amounts of drugs found in body fluids and tissues at death are related to the time since ingestion and, within the limits of experimental error, obey Fick's law.


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