scholarly journals Acute Intrinsic Renal Failure IV: Peritoneal Dialysis Treatment

Critical Care ◽  
2021 ◽  
pp. 100-101
Author(s):  
Robert J. Murtaugh
1988 ◽  
Vol 11 (3) ◽  
pp. 181-185 ◽  
Author(s):  
J. Woo ◽  
A. Leung ◽  
K. Chan ◽  
K.N. Lai ◽  
R. Teoh

We measured pyrazinamide and rifampicin plasma concentrations in five patients with pulmonary tuberculosis and end stage renal failure treated by haemodialysis or continuous ambulatory peritoneal dialysis. Using conventional daily doses of oral pyrazinamide and rifampicin, we found that the drugs were removed efficiently by both dialysis methods, so that plasma levels were sub-optimal for maximal bactericidal action. These findings suggest that in patients with tuberculosis on maintenance dialysis, treatment should be either with higher doses of these two drugs, or with additional replacement doses given after each dialysis. Further detailed pharmacokinetic studies on larger numbers of patients are indicated.


2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Stefano Sbrignadello ◽  
Giovanni Pacini ◽  
Andrea Tura

The measurement of glycemia in subjects with renal failure, thus treated with hemodialysis, or peritoneal dialysis, is clinically relevant, since glucose levels may influence the determination of other solutes, such as creatinine, as well as some ions, such as sodium, whose degree of removal during dialysis sessions should be controlled carefully. Also, glucose levels should be controlled to avoid possible events of hypoglycemia during the treatment, especially in diabetic subjects. Indeed, even cases of hypoglycemic coma are documented. The glucose measurement during the dialysis treatment can be performed with different sensors and technologies: for instance, with traditional glucose meters, with instruments for continuous glucose monitoring, or with optical sensors. The aim of this review study was to analyze these different approaches and briefly discuss possible advantages and limitations.


2005 ◽  
Vol 58 (11-12) ◽  
pp. 576-581
Author(s):  
Natasa Jovanovic ◽  
Mirjana Lausevic ◽  
Biljana Stojimirovic

Introduction During the last years, an increasing number of patients with end-stage renal failure caused by various underlying diseases, all over the world, is treated by renal replacement therapy. Nutritional status Malnutrition is often found in patients affected by renal failure; it is caused by reduced intake of nutritional substances due to anorexia and dietary restrictions hormonal and metabolic disorders, comorbid conditions and loss of proteins, amino-acids, and vitamins during the dialysis procedure itself. Nutritional status significantly affects the outcome of patients on chronic dialysis treatment. Recent epiodemiological trials have proved that survival on chronic continuous ambulatory peritoneal dialysis program depends more on residual renal function (RRF) than on peritoneal clearances of urea and creatinine. Material and methods The aim of the study was to analyze the influence of RRF on common biochemical and anthropometric markers of nutrition in 32 patients with end-stage renal failure with various underlying diseases during the first 6 months on continuous ambulatory peritoneal dialysis (CAPD). The mean residual creatinine clearance was 8,3 ml/min and the mean RRF was 16,24 week in our patients at the beginning of the chronic peritoneal dialysis treatment. Results and conclusion During the follow-up, the RRF slightly decreased, while the nutritional status of patients significantly improved. Gender and age, as well as the leading disease and peritonitis didn't influence the RRF during the first 6 months of CAPD treatment. We found several positive correlations between RRF and laboratory and anthropometric markers of nutrition during the follow-up, proving the positive influence of RRF on nutritional status of patients on chronic peritoneal dialysis.


2008 ◽  
Vol 149 (1) ◽  
pp. 5-11 ◽  
Author(s):  
Kálmán Polner

A szerző rövid áttekintést ad a peritonealis dialíziskezelés történetéről, kiemelve két magyar nefrológus, Stephen I. Vas és Taraba István munkásságának jelentőségét. A peritonealis dialíziskezelés fejlődése oda vezetett, hogy mára a hemodialízissel egyenrangú vesepótló kezelés lett. A maradék vesefunkció megőrzésével az első két évben a morbiditási, mortalitási mutatók és a betegek életminősége vonatkozásában felül is múlja azt. Gazdasági szempontból egyértelműen előnyösebb a hemodialízisnél, ezért az egyre több veseelégtelen beteg ellátásában várhatóan még nagyobb szerepet fog kapni. Az utóbbi években a technológia fejlődése és az automata peritonealis dialíziskezelések elterjedése is a minőség javítását segíti. A peritonealis dialíziskezelés a beteg önkezelése révén új kapcsolatrendszert alakít ki a betegek és az egészségügyi személyzet között, fokozódik a betegoktatás igénye, javul a betegek önbecsülése, együttműködése, ami összességében jobb rehabilitációs esélyeket és jobb életminőséget eredményez. A hazai peritonealis dialíziskezelés még elmarad az európai átlagtól, de a fejlődés dinamikus, és várhatóan a betegek száma is tovább fog növekedni.


1980 ◽  
Vol 3 (4) ◽  
pp. 203-208
Author(s):  
B.T. Burton

Today, management of irreversible renal failure is based primarily on maintenance hemodialysis and renal transplantation with a growing minority of patients treated by peritoneal dialysis. With regard to renal transplantation — the early promise of renal transplantation in the mid 1960's has given way to the realities of the late 1970's. There have been no major changes in the rejection rate of transplanted kidneys in recent years though today's mortality of transplant patients is considerably reduced over what it used to be. Moreover, universally the lack of availability of a sufficient number of organs for transplantation poses a formidable problem. It is all too apparent that current methods of blood purification in uremia are far from optimal. Even though the mortality in maintenance dialysis is relatively low, hemodialysis is characterized by a variety of complications and most maintenance dialysis patients are not optimally rehabilitated.


1996 ◽  
Vol 16 (2) ◽  
pp. 158-162 ◽  
Author(s):  
Marion Haubitz ◽  
Reinhard Brunkhorst ◽  
Eike Wrenger ◽  
Peter Froese ◽  
Matthias Schulze ◽  
...  

Objective Evaluation of the inflammatory activity in patients on chronic peritoneal dialysis (PD) and patients on chronic hemodialysis (HD) in comparison to patients with chronic renal insufficiency without dialysis treatment and healthy volunteers. Design Open, non randomized prospective study. Setting Nephrology Department, including HD and PD therapy in a university hospital. Patients Twenty -four patients on chronic PD, 21 patients on chronic HD therapy using a cuprophan dialyzer, 16 patients with chronic renal insufficiency without dialysis treatment, and 33 healthy volunteers; 8 additional patients before and after initiation of chronic HD therapy. All patients and controls were without infection or immunosuppressive therapy. Main Outcome Measures As a marker of the inflammatory activity in the different patient groups, C-reactive protein (CAP) was measured serially using a sensitive, enzyme-Iinked, immunosorbent assay in order to detect values below the detection limit of standard assays. Results All patient groups had CAP levels higher than the normal controls (p < 0.01). Patients on HD had CAP levels significantly higher than PD patients (p < 0.01) whose levels were comparable to patients without dialysis therapy. Accordingly, longitudinal measurements before and after initiation of chronic HD showed a significant increase in CAP levels after the beginning of HD treatment (p < 0.04). Conclusions The results suggest that induction of the inflammatory activity is lower during PD compared to HD, since stimulation by the dialyzer membrane, dialysate buffer, or bacterial fragments in the dialysate is avoided. This observation might indicate a possible lower risk of long-term complications in patients with PD.


Renal Failure ◽  
1997 ◽  
Vol 19 (1) ◽  
pp. 165-170 ◽  
Author(s):  
H. S. Kohli ◽  
A. Barkataky ◽  
R. S. Vasanth Kumar ◽  
K. Sud ◽  
V Jha ◽  
...  

Author(s):  
Elżbieta Kimak ◽  
Andrzej Książek ◽  
Janusz Solski

AbstractStudies were carried out in 183 non-dialyzed, 123 hemodialysis, 81 continuous ambulatory peritoneal dialysis and 35 post-transplant patients and in 103 healthy subjects as a reference group. Lipids and apolipoprotein (apo)AI and apoB were determined using Roche kits. An anti-apoB antibody was used to separate apoB-containing apoCIII and apoE-triglyceride-rich lipoprotein (TRL) in the non-high-density lipoprotein (non-HDL) fraction from apoCIIInonB and apoEnonB in the HDL fraction in four groups of patients with chronic renal failure (CRF) and healthy subjects. Multivariate linear regression analysis was used to investigate the relationship between triglyceride (TG) or HDL-cholesterol (HDL-C) concentrations and lipoproteins. Dyslipidemia varied according to the degree of renal insufficiency, the type of dialysis and therapy regime in CRF patients. Lipoprotein disturbances were manifested by increased TG, non-HDL-C and TRL concentrations, and decreased HDL-C and apoAI concentrations, whereas post-renal transplant patients showed normalization of lipid and lipoprotein profiles, except for TG levels and total apoCIII and apoCIIInonB. The present study indicates that CRF patients have disturbed lipoprotein composition, and that hypertriglyceridemia and low HDL-C concentrations in these patients are multifactorial, being secondary to disturbed lipoproteins. The method using anti-apoB antibodies to separate apoB-containing lipoproteins in the non-HDL fraction from non-apoB-containing lipoproteins in HDL can be used in the diagnosis and treatment of patients with progression of renal failure or atherosclerosis. The variability of TG and HDL-C concentrations depends on the variability of TRL and cholesterol-rich lipoprotein concentrations, but the decreases in TG and increases in HDL-C concentrations are caused by apoAI concentration variability. These relationships, however, need to be confirmed in further studies.


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