Biodegradable Polymers and Drug Delivery

Author(s):  
Manju Rawat ◽  
Swarnlata Saraf

Currently, drug delivery technologies for protein and peptide delivery mainly rely on biodegradable polymers. However, protein stability during release from these systems can be critical due to physical and chemical instabilities. Lipospheres are solid microparticles composed of fat core stabilized by phospholipids layer represent an alternative carrier for the delivery of highly challenging, labile and unstable  substances. This review highlights various aspects of lipospheres like physicochemical characteristics and stability for better clinical utility with a wider spectrum of proteins and peptides.


Author(s):  
Jay Prakash Jain ◽  
Wubeante Yenet Ayen ◽  
Abraham J. Domb ◽  
Neeraj Kumar

2019 ◽  
Vol 16 (8) ◽  
pp. 795-813 ◽  
Author(s):  
Ana Cláudia Lima ◽  
Helena Ferreira ◽  
Rui L. Reis ◽  
Nuno M. Neves

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