A Systematic Approach of Employing Quality by Design Principles: Risk Assessment and Design of Experiments to Demonstrate Process Understanding and Identify the Critical Process Parameters for Coating of the Ethylcellulose Pseudolatex Dispersion Using Non-Conventional Fluid Bed Process

2016 ◽  
Vol 18 (4) ◽  
pp. 1135-1157 ◽  
Author(s):  
Bhaveshkumar H. Kothari ◽  
Raafat Fahmy ◽  
H. Gregg Claycamp ◽  
Christine M. V. Moore ◽  
Sharmista Chatterjee ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Design Of Experiments ◽  
Process Parameters ◽  
Quality By Design ◽  
Systematic Approach ◽  
Design Principles ◽  
Process Understanding ◽  
Fluid Bed ◽  
Critical Process Parameters ◽  
Critical Process

scholarly journals Designing ultra-small nanostructured lipid carriers: critical process parameters

2020 ◽  
Author(s):  
Maria Mendes ◽  
João Basso ◽  
João Sousa ◽  
Alberto Pais ◽  
Carla Vitorino
Keyword(s):  
Process Parameters ◽  
Nanostructured Lipid Carriers ◽  
Critical Process Parameters ◽  
Critical Process

scholarly journals Application of Statistical Design to Assess the Critical Process Parameters of Ethanol Injection Method for the Preparation of Liposomes

2019 ◽  
Vol 18 (1) ◽  
pp. 103-111 ◽  
Author(s):  
Sayani Bhattacharyya ◽  
Bharani S Sogali
Keyword(s):  
Particle Size ◽  
Process Parameters ◽  
Particle Size Analysis ◽  
Polydispersity Index ◽  
Size Analysis ◽  
Ethanol Injection ◽  
Injection Method ◽  
Critical Process Parameters ◽  
Critical Process ◽  
Ethanol Injection Method

In the present study custom screening design was employed to observe the effect of four critical process parameters on particle size and polydispersity index of the liposomal formulation made by ethanol injection method. The four process parameters selected were lipid ratio, rate of injection, phase volume ratio and rotational speed of magnetic stirring. Eight different liposomal formulations were prepared using the design. The formulations were subjected to particle size analysis. The analysis was done at a significance level p<0.05 and found that the process parameters had significant effect on the particle size and polydispersity index of the formulations. The design was optimized for the individual responses with an overall desirability of more than 50%. Three batches of liposomes were formulated at optimized process parameters which matched the target as predicted by the design. Therefore, it can be concluded that the design was effective in production of nano sized stable monodisperse liposomes by ethanol injection method. Dhaka Univ. J. Pharm. Sci. 18(1): 103-111, 2019 (June)

scholarly journals Aeration and Shear Stress Are Critical Process Parameters for the Production of Oncolytic Measles Virus

2019 ◽  
Vol 7 ◽  
Author(s):  
Tanja A. Grein ◽  
Daniel Loewe ◽  
Hauke Dieken ◽  
Tobias Weidner ◽  
Denise Salzig ◽  
...  
Keyword(s):  
Shear Stress ◽  
Process Parameters ◽  
Measles Virus ◽  
Critical Process Parameters ◽  
Critical Process

Experimental Study on Critical Process Parameters Regarding Tension Stringing Construction of 1250mm2 Large-Section Conductor

2013 ◽  
Vol 448-453 ◽  
pp. 2036-2039
Author(s):  
Chun Hua Hu ◽  
Yong Jun Xia ◽  
Junz Hang Li
Keyword(s):  
Experimental Study ◽  
Process Parameters ◽  
Construction Process ◽  
Test Plan ◽  
Large Section ◽  
Critical Process Parameters ◽  
Critical Process ◽  
Test Rack

Critical construction process parameters and necessity of experimental study concerning tension stringing of large-section conductor are elaborated in this paper and in addition, test details related to critical process parameters of tension stringing construction is researched by citing the example of 1250mm2 large-section conductor, according to which test plan is worked out and test rack is designed.

Sign in / Sign up

Export Citation Format

Share Document