scholarly journals Glucose-Induced Expression of the Cyclin-Dependent Protein Kinase 5 Activator p35 Involved in Alzheimer’s Disease Regulates Insulin Gene Transcription in Pancreatic β-Cells

Endocrinology ◽  
2004 ◽  
Vol 145 (6) ◽  
pp. 3023-3031 ◽  
Author(s):  
Mariano Ubeda ◽  
Daniel M. Kemp ◽  
Joel F. Habener
Keyword(s):  
Alzheimer’S Disease ◽  
Protein Kinase ◽  
Gene Transcription ◽  
Insulin Gene ◽  
Β Cells ◽  
Pancreatic Β Cells ◽  
Dependent Protein Kinase ◽  
Induced Expression ◽  
Dependent Protein ◽  
Insulin Gene Transcription

Calcium/calmodulin-dependent protein kinase IV involvement in the pathophysiology of glucotoxicity in rat pancreatic β-cells

Metabolism ◽  
2011 ◽  
Vol 60 (1) ◽  
pp. 145-153 ◽  
Author(s):  
Yasunori Sugiyama ◽  
Koji Murao ◽  
Hitomi Imachi ◽  
Noriyuki Sueyoshi ◽  
Toshihiko Ishida ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Β Cells ◽  
Pancreatic Β Cells ◽  
Dependent Protein Kinase ◽  
Calcium Calmodulin Dependent ◽  
Dependent Protein

scholarly journals Non-genomic actions of 17β-oestradiol in mouse pancreatic β-cells are mediated by a cGMP-dependent protein kinase

1999 ◽  
Vol 521 (2) ◽  
pp. 397-407 ◽  
Author(s):  
Ana B. Ropero ◽  
Esther Fuentes ◽  
Juan M. Rovira ◽  
Cristina Ripoll ◽  
Bernat Soria ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Β Cells ◽  
Pancreatic Β Cells ◽  
Dependent Protein Kinase ◽  
Cgmp Dependent Protein Kinase ◽  
Dependent Protein

Short-term regulation of insulin gene transcription

2002 ◽  
Vol 30 (2) ◽  
pp. 312-317 ◽  
Author(s):  
B. Leibiger ◽  
T. Moede ◽  
S. Uhles ◽  
P.-O. Berggren ◽  
I. B. Leibiger
Keyword(s):  
Insulin Secretion ◽  
Gene Transcription ◽  
Insulin Gene ◽  
Current View ◽  
Β Cells ◽  
Pancreatic Β Cells ◽  
Short Term ◽  
Major Nutrient ◽  
Glucose Metabolites ◽  
Insulin Gene Transcription

Short-term regulation of insulin gene transcription is still a matter of debate. However, an increasing body of evidence shows that insulin gene transcription is affected by signals, such as incretins, glucose metabolites, intracellular Ca2+, and by insulin secreted from pancreatic β-cells, all supporting the concept of an immediate response resulting in insulin gene transcription following food-uptake. The present review aims to summarize the current view on the mechanisms underlying the up-regulation of insulin gene transcription in response to glucose, the major nutrient factor in insulin secretion and biosynthesis.

scholarly journals Regulation of Insulin Gene Transcription by ERK1 and ERK2 in Pancreatic β Cells

2003 ◽  
Vol 278 (35) ◽  
pp. 32969-32977 ◽  
Author(s):  
Shih Khoo ◽  
Steven C. Griffen ◽  
Ying Xia ◽  
Richard J. Baer ◽  
Michael S. German ◽  
...  
Keyword(s):  
Gene Transcription ◽  
Insulin Gene ◽  
Β Cells ◽  
Pancreatic Β Cells ◽  
Insulin Gene Transcription

scholarly journals Covalent Histone Modifications Underlie the Developmental Regulation of Insulin Gene Transcription in Pancreatic β Cells

2003 ◽  
Vol 278 (26) ◽  
pp. 23617-23623 ◽  
Author(s):  
Swarup K. Chakrabarti ◽  
Joshua Francis ◽  
Suzanne M. Ziesmann ◽  
James C. Garmey ◽  
Raghavendra G. Mirmira
Keyword(s):  
Gene Transcription ◽  
Histone Modifications ◽  
Developmental Regulation ◽  
Insulin Gene ◽  
Β Cells ◽  
Pancreatic Β Cells ◽  
Covalent Histone Modifications ◽  
Insulin Gene Transcription
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