Insulin Secretion in Aging: Studies with Sequential Gating of Secretion Vesicle Margination and Lysis*

Endocrinology ◽  
1986 ◽  
Vol 119 (2) ◽  
pp. 827-832 ◽  
Author(s):  
MARC GOODMAN ◽  
J. WAYNE LEITNER ◽  
KARL E. SUSSMAN ◽  
BORIS DRAZNIN
Keyword(s):  
Insulin Secretion ◽  
Aging Studies ◽  
Sequential Gating

Intraisiet somatostatin inhibits insulin secretion via SSTR5 in the isolated perfused mouse pancreas model

2001 ◽  
Vol 120 (5) ◽  
pp. A133-A133
Author(s):  
T TIRONE ◽  
S MOLDOVAN ◽  
M NORMAL ◽  
F DEMAYO ◽  
F CHARLESBRUNICARDI
Keyword(s):  
Insulin Secretion ◽  
Mouse Pancreas

SPONTANEOUS HYPOGLYCAEMIA AND SARCOMA

1965 ◽  
Vol 50 (2) ◽  
pp. 233-238 ◽  
Author(s):  
J. A. R. Friend ◽  
C. N. Hales
Keyword(s):  
Insulin Secretion ◽  
Plasma Insulin ◽  
Slow Growing ◽  
Insulin Like Activity

ABSTRACT A patient with a slow-growing fibrosarcoma of ovarian origin developed attacks of hypoglycaemia. Estimations of plasma insulin-like activity and immunoassay of plasma insulin under a variety of conditions showed no evidence of abnormal insulin secretion. In addition, the responses to glucagon, tolbutamide, and L-leucine showed no definite abnormality. Possible mechanisms for the occurrence of the hypoglycaemia are discussed.

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