Progesterone Augments Copper-Prostaglandin E2Stimulation of the Release of Gonadotropin-Releasing Hormone From Explants of the Median Eminence of Immature Female Rats: An Estrogen-Dependent Process*

Endocrinology ◽  
1988 ◽  
Vol 122 (5) ◽  
pp. 2143-2149 ◽  
Author(s):  
KALA R. BHASKER ◽  
AYALLA BARNEA
Keyword(s):  
Median Eminence ◽  
Gonadotropin Releasing Hormone ◽  
Female Rats ◽  
Immature Female ◽  
Releasing Hormone ◽  
Dependent Process

Effect of gonadotropin-releasing hormone antagonist on ovarian and uterine weights in immature female rats

2002 ◽  
Vol 16 (4) ◽  
pp. 367-369 ◽  
Author(s):  
Masahiro Takeyoshi ◽  
Masakuni Sawaki ◽  
Shuji Noda ◽  
Takako Muroi ◽  
Kanji Yamasaki
Keyword(s):  
Gonadotropin Releasing Hormone ◽  
Female Rats ◽  
Immature Female ◽  
Releasing Hormone

Excitatory Amino Acids Act on the Median Eminence Nerve Terminals to Induce Gonadotropin-Releasing Hormone Release in Female Rats

1998 ◽  
Vol 112 (3) ◽  
pp. 372-382 ◽  
Author(s):  
Shin-ichi Kawakami ◽  
Masumi Ichikawa ◽  
Kumiko Murahashi ◽  
Kanjun Hirunagi ◽  
Hiroko Tsukamura ◽  
...  
Keyword(s):  
Amino Acids ◽  
Median Eminence ◽  
Excitatory Amino Acids ◽  
Gonadotropin Releasing Hormone ◽  
Female Rats ◽  
Nerve Terminals ◽  
Hormone Release ◽  
Releasing Hormone

IN-VITRO STUDIES OF THE EFFECTS OF OESTROGEN PRETREATMENT ON THE SENSITIVITY OF THE IMMATURE FEMALE RAT PITUITARY GLAND TO STIMULATION WITH GONADOTROPHIN RELEASING HORMONE

1977 ◽  
Vol 74 (1) ◽  
pp. 11-21 ◽  
Author(s):  
M. WILKINSON ◽  
D. DE ZIEGLER ◽  
DANIELLE CASSARD ◽  
K. B. RUF
Keyword(s):  
Pituitary Gland ◽  
Brain Lesion ◽  
Culture Technique ◽  
Female Rats ◽  
Female Rat ◽  
Immature Female ◽  
Releasing Hormone ◽  
Gonadotrophin Releasing Hormone ◽  
Unilateral Brain Lesion

The effects of oestrogen priming on the sensitivity of the anterior pituitary gland to stimulation with gonadotrophin releasing hormone (GnRH) was investigated in immature female rats using a new organ culture technique. Hemipituitary glands obtained from animals primed with a single dose of oestradiol benzoate (OB; 20 μg/100 g body weight) released significantly more LH when pulsed with GnRH (4 nmol/l) than did control hemipituitary glands. This potentiating effect was detectable as early as 5 days after birth. After a second stimulation, LH secretion remained high. These results were compared with those obtained from animals treated to induce increased levels of endogenous oestrogen on day 26 of life. Thus, hemipituitary glands were obtained from animals given two injections of OB, an injection of pregnant mare serum gonadotrophin (PMSG) or a unilateral brain lesion placed in the basal hypothalamus. Pituitary tissue was stimulated as before with a pulse of GnRH. Two injections of OB enhanced the sensitivity to stimulation. Conversely, both PMSG and lesion treatment severely reduced the sensitivity to GnRH, although PMSG-treated and lesioned animals have been used as models for the study of ovulation.

scholarly journals Response to the gonadotropin releasing hormone agonist leuprolide in immature female sheep androgenized in utero

2005 ◽  
Vol 38 (2-3) ◽  
Author(s):  
SERGIO E RECABARREN ◽  
TERESA SIR-PETERMANN ◽  
ALEJANDRO LOBOS ◽  
ETHEL CODNER ◽  
PEDRO P ROJAS-GARCÍA ◽  
...  
Keyword(s):  
In Utero ◽  
Gonadotropin Releasing Hormone ◽  
Immature Female ◽  
Releasing Hormone ◽  
Gonadotropin Releasing Hormone Agonist ◽  
Female Sheep

SERUM LUTEINIZING HORMONE AND FOLLICLE-STIMULATING HORMONE CONCENTRATIONS IN IMMATURE FEMALE RATS TREATED WITH MULTIPLE INJECTIONS AND VARIOUS AMOUNTS OF LUTEINIZING HORMONE RELEASING HORMONE

1975 ◽  
Vol 66 (1) ◽  
pp. 13-20 ◽  
Author(s):  
D. C. JOHNSON ◽  
R. S. MALLAMPATI
Keyword(s):  
Luteinizing Hormone ◽  
Constant Stimulus ◽  
Female Rats ◽  
Intact Female ◽  
Immature Female ◽  
Luteinizing Hormone Releasing Hormone ◽  
Releasing Hormone ◽  
Serum Luteinizing Hormone ◽  
Serum Lh ◽  
Lh Rh

SUMMARY Release of immunoreactive LH and FSH was induced in immature intact female rats by repeated injections of synthetic luteinizing hormone releasing hormone (LH-RH). Altering the dose of LH-RH (5, 10, 20, 50 ng) and the frequency of administration (every 10, 20, 30 or 60 min) over a period of 2 h produced a variety of serum LH and FSH concentrations and ratios. When the dose was a constant 20 ng but the frequency of injections was either 20 or 30 min, a steady state in serum gonadotrophin concentrations was reached within 1 h and the level remained the same during the second hour. When given every 10 min, 20 ng LH-RH produced a much higher concentration of both LH and FSH during the second hour of stimulation. Examination of the gonadotrophin levels after each injection of LH-RH showed that the pituitary response was variable in spite of a constant stimulus.

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