HUMAN ALPHA FETOPROTEIN ENHANCES EPIDERMAL GROWTH FACTOR PROLIFERATIVE ACTIVITY UPON PORCINE GRANDLOSA CELLS IN MONOLAYER CULTURE

Endocrinology ◽  
1990 ◽  
Vol 126 (1) ◽  
pp. 669-671 ◽  
Author(s):  
Juan A. Leal ◽  
Jeffrey V. May ◽  
Brooks A. Keel
Keyword(s):  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Proliferative Activity ◽  
Monolayer Culture ◽  
Alpha Fetoprotein ◽  
Epidermal Growth

Perinatal Development of the Rat Kidney: Proliferative Activity and Epidermal Growth Factor

Neonatology ◽  
2001 ◽  
Vol 79 (1) ◽  
pp. 46-53 ◽  
Author(s):  
Toshiya Okada ◽  
Asako Iwamoto ◽  
Ken Kusakabe ◽  
Masafumi Mukamoto ◽  
Yasuo Kiso ◽  
...  
Keyword(s):  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Proliferative Activity ◽  
Rat Kidney ◽  
Perinatal Development ◽  
Epidermal Growth

Plasma concentrations and urinary excretion of mouse epidermal growth factor associated with the inhibition of food consumption and of wool growth in Merino wethers

1982 ◽  
Vol 94 (2) ◽  
pp. 191-202 ◽  
Author(s):  
B. A. Panaretto ◽  
G. P. M. Moore ◽  
D. M. Robertson
Keyword(s):  
Body Weight ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Food Consumption ◽  
Proliferative Activity ◽  
Dose Range ◽  
Plasma Concentrations ◽  
Inhibitory Effects ◽  
Wool Growth ◽  
Epidermal Growth

Twenty-four adult Merino wethers were given mouse epidermal growth factor (mEGF) subcutaneously at doses ranging from 0·02 to 0·12 mg/kg body weight or intravenously in the dose range 010 to 0·14 mg/kg body weight for periods ranging from 3 to 48 h. Plasma concentrations of mEGF were measured by radioimmunoassay and effects of treatment on food consumption and wool growth were observed. Plasma concentrations of the protein sustained for 15–24 h at about 20 ng mEGF/ml (or exceeding this) almost invariably caused feed rejection and casting of the fleeces. This last result clearly indicated disruption of proliferative activity among the replicating cells in wool follicles which regulate wool growth. The inhibitory effects on appetite and wool growth of smaller doses of the protein and of plasma concentrations equal to those above which were sustained for shorter periods have also been examined. Approximately 10% of the dose of mEGF appeared in the urine of three sheep 1 to 3 days after the start of s.c. infusions of 5 mg for 7 h.

Expression of Epidermal Growth Factor Receptor and Proliferative Activity of Cyst Epithelium in Human Renal Cystic Diseases

2006 ◽  
Vol 76 (3) ◽  
pp. 269-273 ◽  
Author(s):  
Eva Compérat ◽  
Sophie Ferlicot ◽  
Philippe Camparo ◽  
Pascal Eschwege ◽  
Nathalie Ba ◽  
...  
Keyword(s):  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Proliferative Activity ◽  
Growth Factor Receptor ◽  
Epidermal Growth ◽  
Renal Cystic Diseases

Antitumor Activity of Alpha Fetoprotein and Epidermal Growth Factor Conjugates in vitro and in vivo

Tumor Biology ◽  
2000 ◽  
Vol 21 (6) ◽  
pp. 367-374 ◽  
Author(s):  
S.V. Lutsenko ◽  
N.B. Feldman ◽  
G.V. Finakova ◽  
N.V. Gukasova ◽  
S.P. Petukhov ◽  
...  
Keyword(s):  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Antitumor Activity ◽  
Alpha Fetoprotein ◽  
Epidermal Growth
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