Growth Hormone Stimulates the Tyrosine Kinase Activity of JAK2 and Induces Tyrosine Phosphorylation of Insulin Receptor Substrates and Shc in Rat Tissues**This work was supported by Fundaćao de Amparo a Pesquisa do Estado de São Paulo and Conselho Nacional de Pesquisa (PRONEX).

Kinase Activity ◽

Rat Tissues ◽

Insulin Receptor Substrates

Hydrogenperoxide (H2O2) stimulates tyrosine-phosphorylation of the insulin receptor and its tyrosine kinase activity in intact cells

Diabetes Research and Clinical Practice ◽

10.1016/0168-8227(87)90092-1 ◽

1987 ◽

Vol 3 ◽

pp. S48-S48

Author(s):

M KASUGA ◽

O KOSHIO ◽

Y AKANUMA

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Kinase Activity ◽

Intact Cells

P-6-1 Hydrogenperoxide (H2O2) stimulates tyrosine-phosphorylation of the insulin receptor and its tyrosine kinase activity in intact cells

Diabetes Research and Clinical Practice ◽

10.1016/s0168-8227(87)80105-5 ◽

1987 ◽

Vol 3 ◽

pp. S48

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Kinase Activity ◽

Intact Cells

Tyrosine phosphorylation of the insulin receptor beta subunit activates the receptor-associated tyrosine kinase activity.

10.1016/s0021-9258(17)42986-3 ◽

1984 ◽

Vol 259 (8) ◽

pp. 5277-5286 ◽

Cited By ~ 66

Author(s):

K T Yu ◽

M P Czech

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Kinase Activity ◽

Beta Subunit ◽

Receptor Beta

Insulin receptor tyrosine kinase activity is reduced in type-2 (non-insulin-dependent) diabetes but not in obesity

Acta Endocrinologica ◽

10.1530/acta.0.114s183 ◽

1987 ◽

Vol 116 (3_Suppl) ◽

pp. S183

Author(s):

H.H. KLEIN ◽

G.R. FREIDENBERG ◽

R.R. HENRY ◽

J.M. OLEFSKY

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Kinase Activity ◽

Insulin Dependent Diabetes ◽

Insulin Receptor Tyrosine Kinase ◽

Insulin Dependent

Effect of streptozocin-induced diabetes on insulin-receptor tyrosine kinase activity in obese Zucker rats

Diabetes ◽

10.2337/diabetes.39.5.619 ◽

1990 ◽

Vol 39 (5) ◽

pp. 619-625 ◽

Cited By ~ 11

Author(s):

L. J. Slieker ◽

E. F. Roberts ◽

W. N. Shaw ◽

W. T. Johnson

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Kinase Activity ◽

Zucker Rats ◽

Insulin Receptor Tyrosine Kinase ◽

Obese Zucker Rats

Substitution of isoleucine for methionine at position 1153 in the beta-subunit of the human insulin receptor. A mutation that impairs receptor tyrosine kinase activity, receptor endocytosis, and insulin action.

10.1016/s0021-9258(18)42456-8 ◽

1992 ◽

Vol 267 (12) ◽

pp. 8383-8389 ◽

Cited By ~ 6

Author(s):

A Cama ◽

M.J. Quon ◽

M de la Luz Sierra ◽

S.I. Taylor

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Human Insulin ◽

Insulin Action ◽

Kinase Activity ◽

Beta Subunit ◽

Receptor Endocytosis ◽

Human Insulin Receptor

A specific type of ganglioside as a modulator of insulin-dependent cell growth and insulin receptor tyrosine kinase activity

10.1016/s0021-9258(20)64355-1 ◽

1991 ◽

Vol 266 (7) ◽

pp. 4531-4537

Author(s):

H Nojiri ◽

M Stroud ◽

S Hakomori

Keyword(s):

Cell Growth ◽

Tyrosine Kinase ◽

Insulin Receptor ◽

Kinase Activity ◽

Insulin Receptor Tyrosine Kinase ◽

Dependent Cell ◽

Insulin Dependent

Specific Inhibition of Insulin-Like Growth Factor-1 and Insulin Receptor Tyrosine Kinase Activity and Biological Function by Tyrphostins

Endocrinology ◽

10.1210/endo.138.4.5092 ◽

1997 ◽

Vol 138 (4) ◽

pp. 1427-1433 ◽

Cited By ~ 83

Author(s):

Marcelina Párrizas ◽

Aviv Gazit ◽

Alexander Levitzki ◽

Efrat Wertheimer ◽

Derek LeRoith

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Insulin Receptor ◽

Kinase Activity ◽

Biological Function ◽

Specific Inhibition ◽

Insulin Like Growth Factor ◽

Insulin Receptor Tyrosine Kinase

Alterations in the tyrosine kinase activity of the insulin receptor produced by in vitro hyperinsulinemia.

10.1016/s0021-9258(17)42444-6 ◽

1986 ◽

Vol 261 (1) ◽

pp. 147-153 ◽

Cited By ~ 7

Author(s):

G Arsenis ◽

J N Livingston

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Kinase Activity ◽

Tyrosine Kinase Activity

Phorbol ester-induced serine phosphorylation of the insulin receptor decreases its tyrosine kinase activity.

10.1016/s0021-9258(18)69090-8 ◽

1988 ◽

Vol 263 (7) ◽

pp. 3440-3447 ◽

Cited By ~ 12

Author(s):

S Takayama ◽

M F White ◽

C R Kahn

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Phorbol Ester ◽

Kinase Activity ◽

Serine Phosphorylation ◽

Tyrosine Kinase Activity