scholarly journals Biochemical Markers of Insulin-Like Growth Factor-I Misuse in Athletes: The Response of Serum IGF-I, Procollagen Type III Amino-Terminal Propeptide, and the GH-2000 Score to the Administration of rhIGF-I/rhIGF Binding Protein-3 Complex

2014 ◽  
Vol 99 (6) ◽  
pp. 2259-2268 ◽  
Author(s):  
Nishan Guha ◽  
Ioulietta Erotokritou-Mulligan ◽  
Christiaan Bartlett ◽  
Simon P. Nevitt ◽  
Michael Francis ◽  
...  
Keyword(s):  
Growth Factor ◽  
Biochemical Markers ◽  
Binding Protein ◽  
Insulin Like Growth Factor ◽  
Type Iii ◽  
Procollagen Type ◽  
Amino Terminal ◽  
Factor I ◽  
Igf I ◽  
Growth Factor I

Colocalization of insulin-like growth factor-binding protein with insulin-like growth factor I

1991 ◽  
Vol 261 (1) ◽  
pp. F22-F28 ◽  
Author(s):  
S. Kobayashi ◽  
D. R. Clemmons ◽  
M. A. Venkatachalam
Keyword(s):  
Growth Factor ◽  
Cultured Cells ◽  
Binding Protein ◽  
Insulin Like Growth Factor ◽  
Intense Staining ◽  
Factor Binding ◽  
Factor I ◽  
Collecting Ducts ◽  
Igf I ◽  
Growth Factor I

We report the localization of insulin-like growth factor I (IGF-I) and a 25-kDa form of insulin-like growth factor-binding protein (IGF-BP-1) in adult rat kidney. The antigens were localized using a rabbit anti-human IGF-I antibody, and a rabbit anti-human IGF-BP-1 antibody raised against human 25-kDa IGF-BP-1 purified from amniotic fluid. Immunohistochemistry by the avidin-biotin peroxidase conjugate technique showed that both peptides are located in the same nephron segments, in the same cell types. The most intense staining was in papillary collecting ducts. There was moderate staining also in cortical collecting ducts and medullary thick ascending limbs of Henle's loop. In collecting ducts the antigens were shown to be present in principal cells but not in intercalated cells. In distal convoluted tubules, cortical thick ascending limbs, and in structures presumptively identified as thin limbs of Henle's loops there was only modest staining. The macula densa, however, lacked immunoreactivity. Colocalization of IGF-I and IGF-BP-1 in the same cells supports the notion, derived from studies on cultured cells, that the actions of IGF-I may be modified by IGF-BPs that are present in the same location.

The development of decision limits for the GH-2000 detection methodology using additional insulin-like growth factor-I and amino-terminal pro-peptide of type III collagen assays

2015 ◽  
Vol 7 (9) ◽  
pp. 745-755 ◽  
Author(s):  
Richard I. G. Holt ◽  
Walailuck Böhning ◽  
Nishan Guha ◽  
Christiaan Bartlett ◽  
David A. Cowan ◽  
...  
Keyword(s):  
Growth Factor ◽  
Type Iii Collagen ◽  
Insulin Like Growth Factor ◽  
Type Iii ◽  
Amino Terminal ◽  
Factor I ◽  
Growth Factor I

scholarly journals Insulin, Insulin-Like Growth Factor I (IGF-I), IGF-Binding Protein-1, Growth Hormone, and Feeding in the Newborn

1998 ◽  
Vol 83 (10) ◽  
pp. 3550-3557 ◽  
Author(s):  
A. L. Ogilvy-Stuart ◽  
S. J. Hands ◽  
C. J. Adcock ◽  
J. M. P. Holly ◽  
D. R. Matthews ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Factor ◽  
Binding Protein ◽  
Insulin Like Growth Factor ◽  
Factor I ◽  
Igf I ◽  
Igf Binding ◽  
Growth Factor I ◽  
Igf Binding Protein

SERUM INSULIN-LIKE GROWTH FACTOR-I (IGF-I) AND IGF BINDING PROTEIN (BP)-1, -3 ADAPTATIONS TO TRAINING

1998 ◽  
Vol 30 (Supplement) ◽  
pp. 173
Author(s):  
R. C. Hickson ◽  
L. P. Koziris ◽  
R. T. Chatterton ◽  
R. T. Groseth ◽  
J. M. Christie ◽  
...  
Keyword(s):  
Growth Factor ◽  
Binding Protein ◽  
Serum Insulin ◽  
Insulin Like Growth Factor ◽  
Factor I ◽  
Igf I ◽  
Igf Binding ◽  
Growth Factor I ◽  
Igf Binding Protein
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